DOE ASPECT Funding Opportunity (DE-FOA-0003647): Executive Summary for Startups

The U.S. Department of Energy has released Accelerating Scale-up and Pre-piloting of Emerging Chemical Technologies (ASPECT), funding opportunity number DE-FOA-0003647, offering up to $58 million to advance chemical production technologies that use domestically sourced biomass and waste feedstocks. The opportunity is issued by the Alternative Fuels and Feedstocks Office (AFFO) within DOE's Critical Minerals and Energy Innovation (CMEI) organization.

ASPECT is built for companies that have moved past proof of concept and need capital to validate, de-risk, and scale a chemical process. Awards are cooperative agreements, cost share is required, and a concept paper is mandatory. If you do not submit a concept paper by October 9, 2026, you cannot submit an application at all.

ASPECT at a Glance

  • Funding opportunity number: DE-FOA-0003647

  • Agency: U.S. Department of Energy, CMEI, Alternative Fuels and Feedstocks Office (AFFO)

  • Total available funding: up to $58,000,000

  • Funding instrument: cooperative agreements (DOE has substantial involvement, including go/no-go authority)

  • Assistance listing: 81.087, Renewable Energy Research and Development

  • Announcement type: Research, Development, and Demonstration

  • Individual awards: $2,000,000 to $10,000,000 under Topic Area 1; $10,000,000 to $20,000,000 under Topic Area 2

  • Expected number of awards: 0 to 7 under Topic Area 1; 0 to 3 under Topic Area 2

  • Minimum cost share: 20 percent for R&D tasks, 50 percent for demonstration and commercial application tasks

  • Project period: 24 to 48 months (Topic Area 1); 24 to 60 months (Topic Area 2)

  • Application process: required concept paper, then Stage 1 by invitation, then Stage 2 by invitation

  • Submission portal: DOE eXCHANGE (eere-exchange.energy.gov)

  • Program email: ASPECT@doe.gov

Key Dates and Deadlines

  • NOFO issued: September 4, 2026

  • Informational webinar: September 11, 2026, 1:00 p.m. ET

  • Concept paper deadline (required): October 9, 2026, 5:00 p.m. ET

  • Stage 1 application deadline: December 1, 2026, 5:00 p.m. ET

  • Stage 2 application deadline: February 12, 2027, 5:00 p.m. ET

  • Anticipated selection notification: April 8, 2027

  • Anticipated award date: April 12, 2027

All deadlines are 5:00 p.m. ET. DOE will not extend deadlines for server congestion or upload problems, and applicants are advised to submit at least 48 hours early. SAM.gov registration alone can take several weeks, so registration work should start now rather than in October.

What DOE Is Actually Trying to Fund

ASPECT exists because U.S. chemical production has fallen more than 8 percent since 2017 while global production grew more than 17 percent. DOE's stated intent is to re-shore chemical manufacturing, reduce import reliance, strengthen domestic supply chains, and build out biomanufacturing capacity using America's biomass and waste resources.

Practically, that means DOE wants processes that convert an approved biomass or waste feedstock into a chemical with a real commercial advantage, backed by techno-economic analysis and an industrial partner who confirms the product is marketable. Two categories of target chemical qualify:

  • Conventional chemicals that already have a market, provided the proposed pathway offers an additional advantage such as strengthening domestic supply chains, reducing imports, lowering cost, reducing pathway toxicity, or enabling significant market growth.

  • Bio-advantaged chemicals that offer advantages in function, cost, or trade and national security benefits, such as enhanced durability, higher production efficiency, or decreased toxicity.

DOE also named two specific areas of interest under Topic Area 1: technologies that can be scaled by using or modifying existing U.S. ethanol fermentation infrastructure, and technologies that produce 3-hydroxypropionic acid. These are not exclusive, but they signal where reviewers expect strong fits.

Key Requirements That Apply to Every Application

  • Justify the target chemical. It must be a conventional or bio-advantaged chemical, with the specific advantage explicitly articulated.

  • Market size. Target chemicals should have annual U.S. production of at least 1 million metric tons. Smaller volumes may be considered with justification, but applications targeting small, niche, or fine chemical markets are specifically not of interest.

  • Industrial partner. An industrial partner such as a chemical manufacturer is required on every project team, under both topic areas. Applications under both topic areas must include at least one for-profit industry entity as either the prime recipient or a subrecipient. If the industrial partner is not the prime applicant, a letter of commitment is required with the application.

  • Approved feedstock. The primary feedstock must appear on the acceptable feedstock list in Appendix A of the NOFO.

  • Verification process. All applicants selected for award negotiations must participate in a third-party verification process led by a non-conflicted DOE verification team.

  • Peer review participation. Attendance and participation at the AFFO Biennial Peer Review Meeting is required.

  • Domestic performance. The project must be located in the United States, and all work must be performed in the United States absent an approved waiver.

  • Analysis. Preliminary techno-economic analysis (TEA) and life cycle analysis (LCA) are required, and Subtopic Area 1b requires detailed TEA and LCA rather than preliminary.

Topic Area 1: Bench ASPECT

Topic Area 1 supports research and development of new chemical production technologies, moving them beyond proof of concept toward bench and pre-pilot scale. Approximate total funding for this topic area is up to $28,000,000, with 0 to 7 awards, individual awards of $2,000,000 to $10,000,000, a 20 percent minimum cost share, project periods of 24 to 48 months, and budget periods of 12 to 24 months.

Subtopic Area 1a: Bench-Scale Technologies

Subtopic 1a is for technologies beyond proof of concept and ready for additional bench-scale process development and optimization at TRL 2. Each project is eligible for up to $5,000,000 in federal funding with a minimum 20 percent cost share. The envisioned structure is Budget Period 1 for verification of application data, a go/no-go decision, then Budget Period 2 for bench-scale work, across 12 to 24 months.

One caution specific to 1a: applications that use model compounds instead of real feedstocks after Budget Period 1 are specifically not of interest.

Subtopic Area 1b: Bench-Scale and Unit Operation Pre-piloting

Subtopic 1b combines bench-scale R&D in Phase 1 (TRL 2) with pre-piloting of one or more unit operations in Phase 2 (TRL 3 or TRL 4). Each project is eligible for up to $10,000,000 in federal funding, structured as up to $5,000,000 for Phase 1 and up to an additional $5,000,000 for Phase 2, with a minimum 20 percent cost share throughout.

The envisioned schedule runs Phase 1 across 18 to 30 months (verification, go/no-go, bench-scale work, pre-pilot design, then a stage gate approving the pre-pilot performance baseline) and Phase 2 across 12 to 18 months (procurement and construction, then commissioning and operations).

Additional 1b requirements include detailed TEA and LCA, the ability to demonstrate during initial verification that the unit operations of interest are at TRL 3 or TRL 4, proof that you can produce the final targeted chemical when the advantaged property appears only in the finished product, and Phase 2 downstream unit operations sized for the process streams produced from 0.5 dry tons per day (DTPD) of feedstock.

Specifically not of interest under 1b: work on heterogeneous catalysts in powder form for thermocatalytic processes, strain discovery for biochemical processes, development of electrocatalytic cells, and use of model compounds instead of real feedstocks in any budget period.

Topic Area 1 Expected Outcome

By the end of the performance period, projects must produce a sufficient quantity of the target chemical at a purity level appropriate for product or formulation testing. The quantity must be defined and justified for the specific chemical and application, and the performance metrics and purity requirements must be established in partnership with a manufacturer so the resulting material is actually marketable.

Topic Area 2: Pre-pilot ASPECT

Topic Area 2 funds the design, construction, and operation of pre-pilot scale facilities that convert alternative feedstocks into chemicals. Approximate total funding is up to $30,000,000, with 0 to 3 awards, individual awards of $10,000,000 to $20,000,000, project periods of 24 to 60 months, and budget periods of 12 to 24 months.

The minimum baseline is TRL 4, with a maximum of TRL 5 at project conclusion. Projects must build an integrated pre-pilot system capable of processing at least 0.5 DTPD of feedstock, and applicants must justify the chosen scale using sound engineering principles, prior-scale data, and scaling factors. DOE offers scaling to roughly 1/100th of a commercial-scale process for continuous operation as an example of an appropriate target.

Note the eligibility restriction here: institutions of higher education can participate in Topic Area 2 only as subrecipients, not as prime recipients.

Subtopic Area 2a: Unit Operation Pre-piloting and Pre-pilot System Integration

Subtopic 2a is for technologies with one or two unit operations that need further investigation on industrially relevant equipment before the integrated system can be designed. Each project is eligible for up to $20,000,000 in federal funding, with no more than $5,000,000 in Phase 1 and up to $15,000,000 in Phase 2. Cost share is 20 percent for Phase 1 activities and 50 percent for Phase 2 activities.

Phase 1 runs 18 to 24 months and covers verification of prior-scale data, unit operation pre-piloting, verification of unit operation results and system data correlation, and pilot design basis definition, with go/no-go decisions between steps. Phase 2 runs 24 to 36 months and covers planning and final design, final design approval, procurement and construction, then commissioning and operations.

Subtopic Area 2b: Pre-pilot System Integration Only

Subtopic 2b is for technologies already at TRL 5, supported by all necessary prior-scale data, and ready to begin design of the 0.5 DTPD pre-pilot facility. Each project is eligible for up to $15,000,000 in federal funding with a minimum 50 percent cost share. Phase 1 is roughly 12 months (verification and design basis definition, with a stage gate approving the pre-pilot performance baseline), and Phase 2 runs 24 to 36 months (final design, design approval, procurement and construction, commissioning and operations).

Topic Area 2 Time-on-Stream Requirements

By project conclusion, Topic Area 2 projects are expected to meet minimum operating hours:

  • Subtopic 2a: 500 cumulative hours per unit operation and 1,500 cumulative hours on the pre-pilot system; 100 continuous hours per unit operation and 1,000 continuous hours on the pre-pilot system.

  • Subtopic 2b: 1,500 cumulative hours and 1,000 continuous hours on the pre-pilot system.

Topic Area 2 applications must also include a block flow diagram (BFD) and supplemental data sheet using the DOE templates on eXCHANGE, and all major equipment in the pre-pilot plant must match the equipment type planned for the eventual commercial facility. If the commercial system uses a fluidized bed, the pre-pilot system must use a fluidized bed. Recipients will also be required to provide anonymized input to DOE's design cases to refine program TEA and LCA models.

Cost Share Requirements

Cost share is calculated as a percentage of total project cost, which includes the government share, FFRDC costs if applicable, and your recipient share. Minimum cost share by subtopic area:

  • Subtopic 1a: 20 percent

  • Subtopic 1b: 20 percent

  • Subtopic 2a: 20 percent for Phase 1, then 50 percent for Phase 2

  • Subtopic 2b: 50 percent

Applications that do not meet the minimum required cost share are deemed ineligible during the initial compliance review. Cost share must come from nonfederal sources unless otherwise allowed by law, and it can be cash, cash equivalents, or in-kind contributions that are verifiable at the time of submission.

Sources that cannot be used include federal funds or federally owned property, cost share derived from programs executed by the Office of Energy Dominance Financing, revenues or royalties from operations beyond the project period, proceeds from the prospective sale of an asset, expenditures reimbursed under another federal program, contributions already counted toward another federal project, and existing data donated as an in-kind contribution. Contractors may not provide cost share, and partial donations of goods or services count as discounts rather than cost share.

Who Is Eligible to Apply

The following domestic entities are eligible as prime recipients and subrecipients: institutions of higher education, for-profit organizations, nonprofit organizations, state and local government entities, and Indian Tribes. To qualify as a domestic entity, the organization must be legally formed in the United States and have a physical location for business operations in the United States.

Participation limits to note:

  • Institutions of higher education may be prime recipients or subrecipients under Topic Area 1, but only subrecipients under Topic Area 2.

  • DOE and non-DOE FFRDCs and other federal agencies and instrumentalities may participate only as subrecipients. The National Energy Technology Laboratory may participate only as a subrecipient.

  • FFRDC effort in aggregate must not exceed 50 percent of total project cost, and FFRDC participation requires written authorization plus a CRADA or technical assistance agreement.

  • Foreign entities are generally not eligible as recipients or subrecipients. A foreign entity may be included only with an explicit written waiver request submitted with the application, and DOE's decision is final and not appealable.

  • Ineligible participants include debarred or suspended entities, entities on the OFAC Specially Designated Nationals list, and 501(c)(4) organizations that engaged in lobbying after December 31, 1995. Entities of Concern are prohibited from participating.

You may submit multiple concept papers if each addresses a distinct and scientifically unique project concept. DOE will consider only one Stage 1 application per eligible concept paper.

Acceptable Feedstocks

Applications proposing a feedstock not on DOE's acceptable list will not be considered. Acceptable feedstocks under ASPECT include:

  • Lignocellulosic feedstocks, including crops, trees, forest residues, and agricultural residues not grown for food

  • Algae, defined as eukaryotic microalgae, macroalgae, and cyanobacteria

  • Organic wet waste, including municipal wastewater sludge and biosolids, food wastes, organic-rich industrial wastewaters, and manure slurries

  • Sorted municipal solid waste, meaning the organic and plastic constituents of the landfill-bound stream

  • Food waste from industrial, commercial, and residential sources

  • Biogas

  • Grain starch from yellow dent feed corn, wheat, and grain sorghum or milo

  • Oilseed crops such as soybeans, cottonseed, sunflower, canola, rapeseed, peanuts, camelina, carinata, and pennycress

  • Construction and demolition waste

  • Waste carbon dioxide from fermentation, biomass combustion, biopower, or other anthropogenic utility and industrial sources

  • Biointermediates, meaning stable intermediate products derived from another acceptable feedstock

Carbon dioxide captured from ambient air is not an acceptable feedstock under this NOFO.

Applications Specifically Not of Interest

DOE will not review these, and the determination cannot be appealed:

  • Applications outside the technical parameters in the program purpose and topic areas

  • Technologies not based on sound scientific principles

  • Applications proposing primary products used solely as fuels

  • Processes targeting food or protein (amino acids excepted) or biomass as the primary product

  • Applications proposing ethanol as a final product

  • Applications proposing pharmaceuticals, nutraceuticals, food additives, or cosmetics as final products

  • Applications using model compounds instead of real feedstocks, excluding Subtopic 1a proposals

  • Applications that do not use an allowable feedstock from Appendix A

  • Technology that is already operating commercially

  • Applications without an industrial entity as applicant or partner

  • Processes targeting small, niche, or fine chemical markets, or potential markets under 1 million metric tons per year, absent justification

The Three-Stage Application Process

Stage 0: Concept Paper (Required)

The concept paper is required for every applicant and is limited to 5 total pages at no smaller than 12-point font. DOE provides a custom abbreviated template on eXCHANGE, and while the template is not mandatory, every element it requests must be addressed. The recommended allocation is 1 page for administrative information and 4 pages for characteristics of the proposed project. Anything beyond 5 pages will not be reviewed and may disqualify the submission.

Concept papers are scored on a single criterion at 100 percent weight: overall NOFO responsiveness and viability of the project. Reviewers confirm that the applicant meets eligibility requirements, that all key requirements and topic-area-specific requirements are addressed, and that the concept does not fall into an area specifically not of interest. Encouraged applicants are invited to submit a Stage 1 application. Decisions are final with no appeal.

Stage 1 Application (By Invitation Only)

Stage 1 is the technical review package. Technical volume page limits by subtopic area:

  • Subtopic 1a: 15 pages

  • Subtopic 1b: 25 pages

  • Subtopic 2a: 30 pages

  • Subtopic 2b: 25 pages

Page limits include the cover page, table of contents, citations, charts, graphs, photos, and all graphics. Required Stage 1 components include the SF-424, technical volume, block flow diagram (Topic Area 2 only, 5 pages), budget justification workbook, a biosketch and current and pending support disclosure for each Covered Individual, a digital persistent identifier such as ORCID for each Covered Individual, research security training certification, and Transparency of Foreign Connections disclosures for the applicant and each subrecipient.

Covered Individuals include the PI, project director, co-PI, co-project director, project manager, and anyone functionally performing those roles. Submitting a biosketch and disclosure for a person acknowledges that DOE designates them as a Covered Individual, which creates an ongoing disclosure obligation for the life of the award.

Stage 2 Application (By Invitation Only)

Stage 2 is the full application, requested only from proposals deemed meritorious in Stage 1. It adds letters of commitment (one page each), a Statement of Project Objectives (10 pages), a Project Management Plan (5 pages), SF-424A and subrecipient budget justifications, FFRDC work proposals and authorizations if applicable, foreign entity waivers if applicable, Impacted Indian Tribes documentation if applicable, a potentially duplicative funding notice, locations of work, an environmental questionnaire, lobbying forms, a one-page public summary, a one-slide summary, a pre-award information sheet, indirect cost rate documentation, and the most recent independent audit.

Documents already submitted at Stage 1 must be resubmitted at Stage 2 if anything has changed.

How Applications Are Scored

Stage 1 applications are evaluated against weighted technical review criteria, with all sub-criteria weighted equally.

Topic Area 1 Criteria

  • Technical Merit, Innovation, and Impact: 40 percent

  • Project Demonstration and Market Transformation Plan: 40 percent

  • Team and Resources: 20 percent

Topic Area 2 Criteria

  • Technical Approach and Impact: 30 percent

  • Financial and Market Viability: 25 percent

  • Management and Organization: 25 percent

  • Workplan: 20 percent

The weighting tells you where to spend your pages. Under Topic Area 1, commercialization and market transformation carry the same weight as the science, so a technically brilliant application with a thin market plan will not score well. Under Topic Area 2, technical merit accounts for less than a third of the score, while financial viability, management capability, and workplan discipline together account for 70 percent. Reviewers at that level are assessing whether your team can actually build and operate a plant on schedule.

Beyond technical review, all applications undergo a Research, Technology, and Economic Security (RTES) due diligence review, and DOE may also conduct pre-selection interviews, pre-selection clarifications, entity risk assessments, and financial capability reviews. DOE's decisions on due diligence reviews are not appealable.

What Happens After Selection

Awards are cooperative agreements, which means DOE shares responsibility for project direction and can intervene, redirect, or stop funding at go/no-go decision points. Several post-award mechanics deserve attention during planning:

  • Verification. Every selectee participates in an initial verification during months 0 to 3, conducted by a non-conflicted third-party team, to confirm the baseline data in your application. This must appear in your scope as Task 1, separated from the rest of the work by a go/no-go decision point, with roughly three months allocated. Intermediate verifications occur at go/no-go points, and a final verification occurs within three months of closeout.

  • Go/no-go reviews and program down-select. Continuation funding depends on technical progress, appropriations, reporting compliance, RTES assessment, and DOE approval of a continuation application. Some projects will not receive funding past a decision point even when they are meeting predefined metrics.

  • Milestones. Workplans require at least one milestone per quarter and at least one SMART technical milestone per year, each with a stated verification method.

  • Davis-Bacon Act requirements apply to awards under this NOFO, including certified weekly payrolls and use of LCPtracker.

  • Buy America Preference applies to infrastructure projects under this NOFO, though it does not apply to prime recipients that are for-profit entities. Equipment and supplies should be American made to the greatest extent practicable.

  • Award negotiation takes at least 60 days, and pre-award costs require written approval from the Grants Officer.

  • Audits. A for-profit recipient expending $1,000,000 or more in DOE awards in a fiscal year requires an annual independent compliance audit. Budget for it.

  • Intellectual property. Small businesses, universities, and nonprofits may elect to retain title to subject inventions under Bayh-Dole. DOE has issued a class patent waiver covering domestic large businesses under this NOFO. The government retains a paid-up nonexclusive license and march-in rights, and U.S. manufacturing commitments apply.

Required Registrations

  • SAM.gov registration with an active Unique Entity Identifier (UEI). This can take several weeks.

  • DOE eXCHANGE account at eere-exchange.energy.gov, with a designated primary and backup point of contact.

  • Grants.gov registration, which requires a Login.gov account, to receive NOFO modification notices.

  • FedConnect registration, required to receive the executed award package. Registration can take up to three days.

How to Position a Competitive ASPECT Concept Paper

The concept paper is a gate, not a beauty contest. It is scored entirely on responsiveness and viability, which means most rejections at this stage are self-inflicted. A strong submission does five things clearly in five pages:

  • Names the target chemical and its advantage in specific terms. Not "a platform chemical with sustainability benefits," but the molecule, the incumbent pathway, the annual U.S. production volume, and the measurable advantage in cost, performance, supply chain, or trade and national security.

  • Names the feedstock from Appendix A. If your process runs on something outside the list, the concept paper will be screened out regardless of technical quality. Ambient-air carbon dioxide is explicitly excluded.

  • Names the industrial partner. A chemical manufacturer on the team who will confirm purity and performance requirements is a requirement, not a differentiator. Missing it is a rejection criterion.

  • Picks the right subtopic honestly. Overreaching into Topic Area 2 without TRL 4 data, or into 2b without complete prior-scale data, invites a bad review. Choosing 1a or 1b with a realistic phase plan is usually the better path for an early-stage company, and 1b provides an on-ramp to pre-pilot work without waiting for a new solicitation.

  • Shows the cost share is real. Cost share must be verifiable at submission. A 50 percent match on a $15,000,000 Subtopic 2b project is a substantial commitment, so the source needs to be identified early, and letters of commitment will be required from third-party contributors.

The two most common reasons strong technologies lose here are structural rather than scientific: a target market under 1 million metric tons per year without a justification, and a commercialization plan that reviewers cannot connect to a specific customer. Both are fixable before October 9.

Frequently Asked Questions

What is the DOE ASPECT funding opportunity?

ASPECT stands for Accelerating Scale-up and Pre-piloting of Emerging Chemical Technologies. It is a DOE Alternative Fuels and Feedstocks Office funding opportunity offering up to $58 million for research, development, and pre-pilot testing of technologies that produce chemicals from domestically sourced alternative and waste feedstocks.

What is the ASPECT funding opportunity number?

The funding opportunity number is DE-FOA-0003647. Applications are submitted through DOE eXCHANGE at eere-exchange.energy.gov, and the program contact is ASPECT@doe.gov.

How much funding is available through ASPECT?

Up to $58,000,000 total. Topic Area 1 (Bench ASPECT) has up to $28,000,000 across 0 to 7 awards, and Topic Area 2 (Pre-pilot ASPECT) has up to $30,000,000 across 0 to 3 awards.

When are ASPECT concept papers due?

Concept papers are due October 9, 2026, at 5:00 p.m. ET. Stage 1 applications are due December 1, 2026, and Stage 2 applications are due February 12, 2027, both at 5:00 p.m. ET.

Is a concept paper required for ASPECT?

Yes. A concept paper is required from every applicant, and it is limited to 5 pages. If you do not submit a concept paper by the deadline, you cannot submit a Stage 1 application. Stage 1 and Stage 2 are both by invitation only.

Who is eligible to apply for ASPECT?

Eligible domestic entities include institutions of higher education, for-profit organizations, nonprofit organizations, state and local government entities, and Indian Tribes. FFRDCs and federal agencies other than DOE may participate only as subrecipients.

Can a university be the prime applicant on ASPECT?

A university can be the prime recipient under Topic Area 1 only. For Topic Area 2, institutions of higher education are eligible to participate solely as subrecipients.

Does ASPECT require an industry partner?

Yes. Every application under both topic areas must include at least one for-profit industry entity, such as a chemical manufacturer, either as the prime recipient or as a subrecipient. If the industrial partner is not the prime applicant, a letter of commitment must accompany the application. Applications without an industrial entity are specifically not of interest.

What is the cost share requirement for ASPECT?

Minimum cost share is 20 percent of total project costs for research and development tasks under Subtopics 1a, 1b, and Phase 1 of 2a. It rises to 50 percent for demonstration and commercial application tasks under Phase 2 of Subtopic 2a and all of Subtopic 2b. Applications below the minimum are ineligible at compliance review.

How large can an individual ASPECT award be?

Subtopic 1a is eligible for up to $5,000,000 in federal funding, Subtopic 1b up to $10,000,000, Subtopic 2a up to $20,000,000 with no more than $5,000,000 in Phase 1, and Subtopic 2b up to $15,000,000.

What feedstocks are acceptable under ASPECT?

Acceptable feedstocks include lignocellulosic biomass, algae, organic wet waste, sorted municipal solid waste, food waste, biogas, grain starch, oilseed crops, construction and demolition waste, waste carbon dioxide, and biointermediates. Carbon dioxide captured from ambient air is not acceptable. Applications using a feedstock outside the list will not be considered.

What kinds of chemicals is DOE looking for?

DOE is looking for conventional chemicals that offer added advantages such as stronger domestic supply chains, reduced imports, lower cost, reduced pathway toxicity, or market growth, and for bio-advantaged chemicals offering advantages in function, cost, or trade and national security, such as greater durability, higher production efficiency, or lower toxicity.

Does my target chemical need 1 million metric tons of annual U.S. production?

Target chemicals should have annual U.S. production of at least 1 million metric tons. Lower volumes may be considered with justification, but applications targeting small, niche, or fine chemical markets are specifically not of interest.

What technology readiness level is required for ASPECT?

Subtopic 1a targets bench-scale work at TRL 2. Subtopic 1b covers TRL 2 bench work in Phase 1 and TRL 3 or TRL 4 unit operation pre-piloting in Phase 2. Topic Area 2 requires a minimum baseline of TRL 4 with a maximum of TRL 5 at project conclusion.

What is the pre-pilot scale requirement under ASPECT?

Pre-pilot unit operations and integrated systems must be sized to handle the process streams produced from at least 0.5 dry tons per day of feedstock. DOE cites scaling to roughly 1/100th of a commercial-scale continuous process as an example of an appropriate target scale.

What applications will DOE reject outright?

DOE will not review applications proposing fuels as the primary product, ethanol as a final product, food or protein (other than amino acids), pharmaceuticals, nutraceuticals, food additives, or cosmetics, technologies already operating commercially, applications using model compounds instead of real feedstocks (except Subtopic 1a), applications without an approved feedstock, and applications without an industrial partner.

How are ASPECT applications scored?

Concept papers are scored on one criterion, overall NOFO responsiveness and viability, at 100 percent weight. Topic Area 1 Stage 1 applications are scored on technical merit, innovation, and impact (40 percent), project demonstration and market transformation plan (40 percent), and team and resources (20 percent). Topic Area 2 is scored on technical approach and impact (30 percent), financial and market viability (25 percent), management and organization (25 percent), and workplan (20 percent).

What is the ASPECT verification process?

Every applicant selected for award negotiations must participate in a verification process led by a non-conflicted third-party team identified by DOE. An initial verification occurs in months 0 to 3 to confirm baseline data from the application, intermediate verifications support go/no-go decisions, and a final verification occurs near closeout. Applicants must include the initial verification as Task 1 in their scope and allow roughly three months for it.

How long are ASPECT projects?

Topic Area 1 project periods run 24 to 48 months and Topic Area 2 project periods run 24 to 60 months, with budget periods of 12 to 24 months. Awards are structured with multiple budget periods and go/no-go decision points, and continuation funding is not guaranteed.

Can a foreign company participate in an ASPECT project?

Foreign entities are generally not eligible as recipients or subrecipients. Participation requires an explicit written waiver request submitted with the application, and DOE's determination is final and cannot be appealed. All work must also be performed in the United States absent a separate approved foreign work waiver.

Are cooperative agreements different from grants under ASPECT?

Yes. ASPECT awards are cooperative agreements, which means DOE has substantial involvement in directing the technical work, participates in major project decisions, and can redirect or stop funding at go/no-go decision points.

Talk to BW&CO Before the October 9 Concept Paper Deadline

ASPECT is a competitive, non-dilutive path to fund pre-pilot scale-up without giving up equity, and the concept paper gate rewards preparation over polish. BW&CO has helped deep tech and industrial innovators secure more than $350M in federal funding by getting the strategy, teaming, and compliance right before the first submission.

If you are evaluating ASPECT, we can help you confirm topic area fit, pressure test your target chemical and market justification, structure your cost share and industrial partnership, and build a concept paper that survives responsiveness review. Innovation Funding Simplified.

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