Deadline: September 30, 2027

Funding Award Size: $300K to $5 Million+

Description: : Funding for advancing technologies that enhance human performance, resilience, and health in aerospace and defense environments.

Deadline: September 30, 2026.

Funding Award Size: $2 million+

Description: Funding for transformative biology-enabled capabilities for national security.

Deadline: January 5, 2026; April 5, 2026; September 5, 2026

Funding Award Size: <$2.1 Million

Description: Funding for research and development toward a commercially viable product or service aligned with the missions of NIH, CDC, or FDA.

Deadline: Estimated: Q4 2025, Q1 2026

Funding Award Size: $75K to $1.8 million

Description: A flexible SBIR/STTR vehicle for technologies with commercial value that could provide similar value to the Space Force or Air Force.

Deadline: July 31, 2028

Funding Award Size: $2 Million to $10 Million

Description: Funding for research and development that advances biomedical solutions, human performance optimization, and medical readiness technologies supporting U.S. Special Operations Forces. Projects may address areas such as damage control resuscitation, prolonged field care, medical sensors and diagnostics, brain health, force protection, canine medicine, or other SOF-relevant capabilities.

Deadline: Rolling basis until March 5, 2029.

Funding Award Size: Typically varies by project scope; proposers should request only what is necessary to reach a meaningful technical milestone—often $2 million or more for high-impact efforts.

Description: Funding for revolutionary solutions that expand equitable access, affordability, and rapid deployment of health innovations across the U.S. healthcare landscape. The SSO ISO supports scalable technologies that enhance distribution, biomanufacturing, and delivery systems to reach every patient efficiently and affordably.

Deadline: Rolling basis until March 5, 2029.

Funding Award Size: Typically varies by project scope; proposers should request only what is necessary to reach a meaningful technical milestone—often $2 million or more for high-impact efforts.

Description: Funding for transformative health system innovations that strengthen the resilience, adaptability, and interoperability of U.S. healthcare. The RSO ISO supports breakthrough solutions that enhance system robustness, improve efficiency, and safeguard access to care during disruptions.

Deadline: Rolling basis until March 5, 2029.

Funding Award Size: Typically varies by project scope; proposers should request only what is necessary to reach a meaningful technical milestone—often $2 million or more for high-impact efforts.

Description: Funding for transformative, prevention-focused innovations that extend health span and avert disease before it occurs. The PHO ISO supports bold solutions in early detection, behavior change, and system-level redesign to build a proactive, resilient, and equitable health future.

Deadline: Rolling basis until March 5, 2029.

Funding Award Size: Typically varies by project scope; proposers should request only what is necessary to reach a meaningful technical milestone—often $2 million or more for high-impact efforts.

Description: Funding for revolutionary, disease-agnostic health innovations that remove scientific and technological barriers to next-generation healthcare. The HSF ISO supports cutting-edge tools, technologies, and platforms with the potential for real-world translational impact.

Deadline: Rolling Basis - Apply ASAP before funds are gone.

Funding Award Size: $10 Million or more.

Description: Funding for research, prototyping, and commercialization projects that advance U.S. microelectronics, including work tied to AI, quantum, biotechnology/biomanufacturing, commercialization of innovation, and standards.