Latest Funding Opportunity Guides
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NIH Small Business Transition Grant for New Entrepreneurs (PAR-27-039 / PAR-27-040): SBIR and STTR Funding for First-Time PIs
Deadline: January 5th, 2027 (estimated)
Budget: Up to $307k (Phase I, prior cycle)
Description: NIH and CDC fund small businesses that hire or promote a first-time PI, pairing SBIR and STTR research funding with mentorship and entrepreneurial training. See funding fit, eligibility, and how to prepare via NIH SBIR and STTR.
ARPA-H SPECTRA ARPA-H-SOL-26-163: Autism Technology and Research Funding Guide for Startups
Deadline: October 18, 2026 (TA4 Solution Summary)
Funding Award Size: Not published (OT awards)
Description: ARPA-H funds wearables, communication devices, and AI tools that improve daily life for autistic people while generating real-world assessment data. See funding fit, technical areas, and how to apply via the ARPA-H Solutions site.
ARPA-H UNIQUE ARPA-H-SOL-26-162: Quantum Entanglement Imaging Program Guide for Startups
Deadline: October 29, 2026 (Solution Summary)
Funding Award Size: Not published (OT awards)
Description: ARPA-H funds teams that turn entangled 511 keV photon pairs into a new kind of medical imaging contrast, paired with quantum-aware AI reconstruction. See funding fit, metrics, and how to apply via the ARPA-H Solutions site.
ARPA-H Emerging Health Innovators (EHI) 2026, ARPA-H-SOL-26-150: Up to $1.05M for Early-Career Researchers
Deadline: October 30, 2026 (Solution Summary)
Funding Award Size: Up to $1.05m
Description: ARPA-H funds early-career researchers at companies, universities, and nonprofits across 16 health topics, from implantable cancer therapy to clinical AI. See funding fit, topics, and how to apply via the ARPA-H Solutions site.
NASA NIAC Phase I FY2027: Up to $225K for Visionary Aerospace Concepts
Deadline: October 28, 2026 (Step A)
Funding Award Size: Up to $225k
Description: NASA’s Space Technology Mission Directorate funds nine-month feasibility studies of visionary, early-stage aerospace concepts through NIAC Phase I. See funding fit, focus areas, and how to apply via NSPIRES.
AFRL HERMES BAA (FA9300-20-S-0001)
Deadline: November 16th, 2026 (4:00 PM PST)
Award Type: Open two-step BAA (contracts, grants, cooperative agreements or OTs)
AFRL’s Rocket Propulsion Division seeks white papers for a rotating detonation rocket engine combined-cycle flight demonstration, while the HERMES BAA stays open. This page covers funding, eligibility, security requirements and how to apply.
DIU Low Cost ISR (LC-ISR) Prize Challenge: Executive Summary for Startups
Deadline: October 14th, 2026
Funding Award Size: Prize challenge with potential prototype OT and follow-on
Description: DIU seeks mature, low-cost medium- and long-endurance ISR drones for expeditionary operations. $100M prize and initial follow-on pool. How it works, who should apply, and how to team.
MedTech Innovator Vantage Non-Dilutive Funding Program: Up to $200K for Health Security Diagnostics and Devices
Deadline: October 15th
Funding Award Size: $50k - $200k
Description: MedTech Innovator and BARDA fund six-month projects advancing health security diagnostics, patient monitoring, and medical devices. See funding fit, priority areas, and how to apply.
TRISH Catalyst Grants Program: NASA-Funded Space Health Awards for Companies and Researchers
Deadline: Rolling through December 2026
Funding Award Size: Up to $150k (Tier 1), $150k+ (Tier 2)
Description: NASA’s Translational Research Institute for Space Health funds proof-of-concept and technology development projects that reduce astronaut health risks. See funding fit, focus areas, and how to apply.
USDA SBIR/STTR Phase II USDA-NIFA-SBIR-012221: Executive Summary for Ag and Food Tech Startups
Deadline: November 17th
Funding Award Size: $600k - $650k
Description: USDA NIFA invites prior Phase I winners to advance agriculture, food, forestry, and rural innovations toward market. See funding fit, topic areas, and how to apply via USDA SBIR and STTR.
DARPA Atomically Precise Molecules (APM) DARPA-PS-26-141: Complete Guide for Proposers
Deadline: October 27th (abstracts), December 18th (proposals)
Funding Award Size: Not published (OT for Prototype awards)
Description: DARPA seeks revolutionary synthesis methods for programmable precision polymers and nonlinear optical materials, starting with sub-nanosecond electro-optic modulators. See funding fit, phases, and how to apply.
Army Advanced Manufacturing (AdvM) Commercial Solutions Opening W9124P26SC001: Complete Guide for Startups
Deadline: Open until canceled (Calls for Solutions have short individual deadlines)
Funding Award Size: Not published (firm-fixed-price awards)
Description: The Army Advanced Manufacturing CSO accepts white papers on 18 capability gap areas at any time, from robotics and additive manufacturing to predictive maintenance. See what it buys, how to submit, and how to prepare for short Calls.
GRA Development Grant: Executive Summary for Georgia Startups
Deadline: Six review cycles per year
Funding Award Size: $10k - $250k
Description: The Georgia Research Alliance funds milestone-driven commercialization projects led by Georgia university faculty. See funding fit, eligible activities, and how to pair it with SBIR and STTR.
FAA Aviation Research BAA 692M15-25-R-00004: Executive Summary for Startups
Deadline: Rolling through December 4th, 2034
Funding Award Size: $100k - $1.2m
Description: The FAA William J. Hughes Technical Center funds aviation safety research across airport pavements, hydrogen, eVTOL controls, AI assurance, and pilot training. See funding fit, focus areas, and how to apply via white paper.
NIH Highlighted Topic: Improving Diagnostic Safety and Quality in Healthcare
Deadline: January 5th
Funding Award Size: $320k - $2m
Description: NIBIB, NCI, and NIDA highlight AI, point-of-care, and digital tools that reduce diagnostic errors and delays. See funding fit, focus areas, and how to apply via NIH SBIR and STTR.
Breakthrough T1D Industry Discovery and Development Partnership (IDDP): Funding, Eligibility, and How to Apply
Deadline: Rolling
Funding Award Size: Negotiated per project (1:1 company match required)
Description: Breakthrough T1D funds for-profit companies developing therapeutics and devices to cure, treat, or prevent type 1 diabetes, with no equity taken. See funding, eligibility, and how to apply.
NIH Highlighted Topic: Microphysiological System Pilot Studies in Diabetes Research
Deadline: January 5th
Funding Award Size: $320k - $2m
Description: NIDDK highlights multi-tissue organ-on-chip models of diabetes and its kidney and urologic complications. See funding fit, focus areas, and how to apply via NIH SBIR and STTR.
NIH Highlighted Topic: Digital Twins for Biomedical, Biological and Behavioral Research
Deadline: January 5th
Funding Award Size: $320k - $2m
Description: NIH ODSS and 18 partner institutes highlight bidirectional digital twins for research and care. See funding fit, focus areas, and how to apply via NIH SBIR and STTR.
DIU CLASS ACT Maritime Counter-Unmanned Systems Opportunity: Executive Summary for Startups
Deadline: October 13th, 2026
Funding Award Size: Prototype OT with follow-on production
Description: DIU seeks cleared nontraditional contractors with maritime counter-UxV sensors and effectors. Eligibility, deadline (Oct 13, 2026), and how to apply.
NIH Highlighted Topic: Advanced Biomaterials for Biomedical Research
Deadline: January 5th
Funding Award Size: $320k - $2m
Description: NCI and NIDCR highlight responsive, programmable biomaterials that better model living tissue. See funding fit, focus areas, and how to apply via NIH SBIR and STTR.