Innovation Funding Database

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

DARPA BTO: Protean

Deadline: March 12, 2026

Funding Award Size: $500k - $2m

Description: DARPA BTO Protean (DARPARA2601) seeks novel protein-level countermeasures against chemical threats. Gate 1 due March 12th, 2026 by 4:00 PM ET.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

DARPA’s Biological Technologies Office has released DARPARA2601: Protean, a high-impact research announcement focused on developing next-generation medical countermeasures that protect critical human proteins from chemical threat agents. This program aims to create prophylactics (and optionally therapeutics) that protect protein function against chemical threat challenges over 10,000x LD50s . Abstracts are due March 12th, 2026 at 4:00pm ET.

How much funding would I receive?

  • Award instruments: Cooperative Agreements or Research Other Transactions (OTs)

  • Period of performance: 33 months total

    • Phase 1 (Base): 18 months

    • Phase 2 (Option): 15 months

  • Funding levels will depend on proposal quality and availability of funds.

What could I use the funding for?

Funding must support work aligned with Protean’s objective: restoring or protecting protein function against chemical threat agents at the mechanistic level .

Focus Areas (You must propose both phases)

You may propose in one or more of the following:

  1. Nerve agents

  2. Synthetic opioids

  3. Ion channel toxins

Work must target DoD-relevant proteins such as:

  • Acetylcholinesterase

  • Mu Opioid Receptor

  • Ion channels

Phase 1 – Non-Classical Protection (18 months)

Funding may support:

  • Discovery of novel regulatory points in protein conformational landscapes

  • Identification of distal regulatory sites (>1 required by Month 6 milestone)

  • Structural biology and computational modeling of bound/unbound conformations

  • Experimental validation of novel conformational states

  • Mechanistic characterization of intoxication pathways

  • In vitro demonstration of functional rescue or protection

  • Demonstrating:

    • 10-fold decrease in threat simulant binding affinity (Month 12)

    • 10x increase in ED50 of >3 threat surrogates (Month 16)

End of Phase 1 requires in vitro evaluation by a government Test & Evaluation (T&E) partner .

Phase 2 – Countermeasure Design (15 months)

Funding may support:

  • Structure-based or ligand-based drug design

  • Optimization of non-competitive chemical matter

  • In vitro and in vivo efficacy improvements

  • Pharmacokinetics and pharmacodynamics studies

  • ADME validation

  • Safety and acute toxicity screening

  • In vivo rodent validation against real CWAs

Key metrics include:

  • 1,000x increase in ED50 in vitro (Month 24)

  • LD50 with intervention >1000x baseline (Month 24, rodent model)

  • 10,000x increase in ED50 in vitro (Month 30)

  • LD50 with intervention >10,000x baseline exposure (Month 33, rodent model)

Are there any additional benefits I would receive?

  • Access to government Test & Evaluation (T&E) partners for real chemical warfare agent testing

  • Potential use of flexible Other Transaction (OT) authority

  • Early technical feedback via invitation-only pre-award sessions (if selected after Gate 1)

  • Opportunity for DoD transition and chemical/biological defense positioning

What is the timeline to apply and when would I receive funding?

Key Dates:

  • Posting Date: February 11th, 2026

  • Protean Virtual Proposers Day: February 20th, 2026

  • Question Submittal Closed: March 9th, 2026 by 4:00 PM ET

  • Gate 1 Due Date (Abstract): March 12th, 2026 by 4:00 PM ET

  • Gate 2 Due Date (Full Proposal): May 7th, 2026 by 4:00 PM ET

Gate 1 selection is required to submit a full proposal.

The program period of performance is 33 months .

Where does this funding come from?

Funding comes from the Defense Advanced Research Projects Agency (DARPA), Biological Technologies Office (BTO) .

Funding Opportunity Number: DARPARA2601
NAICS Code: 541714

Who is eligible to apply?

All responsible sources capable of satisfying the Government's needs, including U.S. and non-U.S. sources, may submit proposals .

  • Historically Black Colleges and Universities, small businesses, small-disadvantaged businesses, and minority institutions are encouraged to apply .

  • Proposers must be registered in SAM and have a valid Unique Entity ID .

  • Proposals must be UNCLASSIFIED or CUI .

  • FFRDCs, UARCs, and Government entities must contact the agency POC prior to submission to discuss eligibility , competitive proposals will:

  • Present highly innovative, non-classical mechanistic approaches

  • Identify >1 novel distal regulatory site by Month 6

  • Demonstrate feasibility across both Phase 1 and Phase 2 metrics

  • Provide experimentally validated structural insights (not purely computational)

  • Show credible in vivo translation plans

  • Demonstrate strong relevance to DoD chemical and biological defense

Proposals that fail to address both phases will be deemed non-conforming .

Are there any restrictions I should know about?

Key restrictions include:

  • Must propose to both Phases

  • Must comply with Controlled Unclassified Information (CUI) handling requirements (NIST 800-171 compliant systems)

  • IP ownership or licensing must be clearly documented

  • Potential publication restrictions for non-fundamental research

  • Organizational Conflict of Interest disclosures required

  • No classified submissions allowed at Gate 1

How long will it take me to prepare an application?

Gate 1 is intentionally streamlined:

  • 10-minute Video Abstract (max 5 slides)

  • 5-page Abbreviated Technical Volume

  • Rough Order of Magnitude cost estimate

Most well-prepared teams should expect 3–6 weeks to develop a competitive Gate 1 submission, depending on technical maturity and team alignment.

Gate 2 preparation will require significantly more effort if invited.

How can BW&CO help?

We help founders and research teams:

  • Reverse-engineer DARPA evaluation criteria

  • Position non-classical mechanisms to align with milestone language

  • Translate structural biology and modeling approaches into milestone-driven narratives

  • Architect Phase 1 → Phase 2 transition logic

  • Draft Gate 1 materials that maximize selection probability

  • Build credible in vivo translation pathways

Our role is to make sure your science aligns exactly with DARPA’s stated metrics and exclusion criteria.

How much would BW&CO Charge?

We charge a flat $4,000 fee to submit the pre-proposal for Gate 1. We also have an hourly rate to strategize, review, and edit applications of $250.

Additional Resources

Review the solicitation here.

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain

Deadline: October 6, 2026

Funding Award Size: $500k - $2m

Description: Apply for NIH BRAIN Initiative R01 funding under RFA-DA-27-004 to develop innovative theories, computational models, and analytical methods for complex brain data. Applications due October 28, 2025; October 6, 2026; and October 6, 2027 (5:00 PM local time).

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The NIH BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (RFA-DA-27-004) is a competitive R01 research grant supporting the development of innovative theories, computational models, and analytical tools to advance understanding of brain function from complex neuroscience data. This funding is part of the NIH BRAIN Initiative, aiming to transform neuroscience through quantitative, predictive frameworks. Applications are due as soon as October 6th, 2026.

How much funding would I receive?

Application budgets are not limited, but NIH expects direct costs of approximately $150,000 – $350,000 per year.

Awards are for up to 3 years of support.

NIH anticipates funding multiple awards each cycle, depending on score and available appropriations.

What could I use the funding for?

Theories of brain function

Development of predictive, mathematically-grounded theories explaining how behavior arises from neural structure, circuit dynamics, computation, cognition, and environmental variables. Examples include:

  • Theories of embodied computation that anchor the neural representation of sensory, cognitive, and motor variables to an individual/animal’s ongoing interactions with the environment through dynamic, moment-to-moment, circular, and iterative processes.

  • Theories that bridge multiple scales of spatial organization (e.g., molecular, synaptic, cellular, circuit, systems) and/or temporal dynamics (e.g., milliseconds to lifetimes) to generate testable predictions of brain-behavior links or cognitive function.

  • Theories linking circuit dynamics and function to specific properties of cell types or anatomical connections, identifying general rules, scaling principles, and contributions of specific circuit motifs to computation.

  • Theories elucidating fundamental computational principles employed by biological neural networks, potentially drawing inspiration from or contrasting with artificial networks, but firmly grounded in biological constraints (e.g., neuronal/synaptic dynamics, connectivity patterns, metabolic limits, specific cell-type properties, learning rules).

Computational models of neural and behavioral dynamics

Development and validation of quantitative models that are mechanistically grounded, interpretable, predictive, and rigorously tested against neural and behavioral data. Examples include:

  • Mechanistic, interpretable, and/or predictive models of neural dynamics, circuit function, or brain-behavior links that integrate biological details with computational principles.

  • Models that integrate knowledge across multiple levels (e.g., linking behavior to neural population activity and cellular/circuit properties).

  • Models of cognitive processing (e.g., sensory coding, decision-making, motor control, learning, memory) that are mechanistically grounded in identified circuit elements and dynamics, make quantitative predictions, and are rigorously tested against neural and behavioral data, potentially under ecologically relevant or challenging conditions (e.g., limited information, dynamic environments).

  • Development and analysis of neural-inspired computational architectures or artificial intelligence/machine learning systems explicitly designed to gain novel insights into brain function.

Methods for complex data analysis

Development of novel computational, statistical, and analytical techniques designed to extract key insights from complex, large-scale neuroscience datasets. Examples include:

  • Development of innovative and scalable computational/statistical methods for dimensionality reduction, identifying latent structure, disentangling contributing factors (e.g., sensory, motor, cognitive, state variables), extracting key dynamical features, or characterizing information flow within large, complex neural and behavioral datasets.

  • Novel approaches for principled data fusion and assimilation to quantitatively integrate heterogeneous datasets (e.g., linking behavior with multi-regional activity, anatomical connectivity, and cell-type information) to infer new theories of brain function, or to constrain and validate multi-scale computational models.

  • Novel statistical/signal processing methods (e.g., component analysis, graphical models, compressed sensing) to track structure in neural data and link to biophysical signals for mechanistic insights across scales.

Are there any additional benefits I would receive?

  • Collaboration with NIH program staff and participation in the broader BRAIN Initiative network.

  • Tools developed are expected to be shared with the neuroscience community, enhancing visibility and impact.

What is the timeline to apply and when would I receive funding?

Application Due Dates (all by 5:00 PM local time):

  • Cycle 2: October 6, 2026

  • Cycle 3: October 6, 2027

Expiration of this NOFO: November 9, 2027

Following review, awards generally begin in March–July of the year after submission.

Where does this funding come from?

This funding is provided by the National Institutes of Health (NIH) through multiple participating Institutes and Centers under the NIH BRAIN Initiative, including NIDA, NEI, NIA, NIAAA, NIBIB, NICHD, NIDCD, NIMH, NINDS, and NCCIH.

Who is eligible to apply?

Eligible applicant organizations include:

  • Higher Education Institutions

  • Nonprofit organizations

  • For-profit organizations (including small businesses)

  • Local/state governments and tribal governments

  • Foreign organizations (with restrictions on foreign subawards)

  • Other research or non-profit entities

Eligible individuals are those qualified to lead the proposed research.

What companies and projects are likely to win?

Strong applicants typically:

  • Propose novel and rigorous theoretical or computational frameworks.

  • Demonstrate deep expertise in neuroscience, modeling, or computational analysis.

  • Have clear plans to validate and share tools with the research community.

  • Show relevance to BRAIN Initiative goals and the integration of complex datasets.

Are there any restrictions I should know about?

  • Clinical trials are not allowed—only research on theory/model/method development.

  • Proposed work must go beyond simple data collection and focus on quantitative theories or analytical tools.

  • Foreign subawards are not permitted; collaborations must be unfunded or through other compliant mechanisms.

How long will it take me to prepare an application?

Plan 4-5 months minimum for:

  • Concept development

  • Budget preparation

  • Letters of support and team coordination

  • Registering with Grants.gov and eRA Commons (if not already completed)

NIH registration processes can take 6+ weeks, so start early.

How can BW&CO help?

BW&CO can assist with:

  • Translating your science aims into NIH-ready specific aims.

  • Coordinating NIH format and submission requirements.

  • Aligning proposal with BRAIN Initiative priorities.

How much would BW&CO Charge?

We have both fractional engagements ($250 an hour) and full engagements ($13,000 + 5%) available.

Additional Resources

Review the solicitation here.

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

NIDDK: Advancing Research on the Application of Digital Health Technology to the Management of Type 2 Diabetes

Deadline: October 6, 2026

Funding Award Size: $500k - $2m

Description: Apply for NIH NIDDK RFA-DK-26-315 funding to conduct clinical trials testing digital health technologies for Type 2 Diabetes management. Applications due October 6, 2026 by 5:00 PM local time

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

NIH/NIDDK is seeking investigator teams to lead clinical trials testing digital health technologies in Type 2 Diabetes management. This R01 requires a clinical trial and aims to build evidence on how digital tools (e.g., continuous glucose monitors, mobile apps, telehealth, wearables) can improve glycemic and related outcomes in people with Type 2 Diabetes. Applications are due October 6, 2026 by 5:00 PM local time — plan ahead to prepare a full clinical trial proposal that adheres to NIH requirements.

How much funding would I receive?

Funds anticipated: Direct costs ~

  • $1.5M in FY2026,

  • $3.0M in FY2027-2030,

  • $1.5M in FY2031.

Award budget: Not capped — must reflect actual needs of the proposed clinical trial project.

Project period: Up to 5 years.

What could I use the funding for?

General principles:

  • Multimodality DHT interventions that for example, combine CGM concurrently with other digital interventions in a virtual remote continuous care intervention, though not required, are of particular interest to this NOFO.

  • All investigators are expected to include meaningful engagement approaches with the relevant research population in designing and implementing the proposed trial. This may involve engagement with patients, family members or caregivers, community members, community-based organization, clinicians and other care providers, health care systems, or other relevant partners throughout the research process. Meaningful engagement must entail more than focus groups, surveys, or other activities where partners are only involved as participants or respondents. Engagement must be designed to ensure that the research is practical and aligns with partners' preferences and values. Meaningful collaboration will lead to optimal trial recruitment and conduct as well as potential for future dissemination and sustainability. 

  • Multiple digital interventions have applicability to management of both T1 and T2 diabetes and these DHT interventions are of interest to this NOFO.

  • Partnering with industry providers of virtual diabetes clinic offerings is allowed but not required.

  • Clinical trials funded in response to this NOFO are expected to provide efficacy data that will enable future large multicenter clinical effectiveness studies on the application of DHT to PWD.

Examples of DHT interventions to be tested include, but are not limited to:

  • Continuous glucose monitoring:

    • Studies on the efficacy of CGM in T2D, including in PWD not taking insulin

    • Studies on the utility of CGM in persons with prediabetes, for example, interventions that prevent the progression of prediabetes to diabetes

    • Studies examining the role of CGM in monitoring and adapting dietary interventions

    • Studies on the dose and duration of CGM usage necessary to effect change in health activation and healthy behaviors

    • Studies to assess and promote the accessibility, adoption and sustainability of CGM interventions

    • Studies assessing and improving the integration of CGM into clinic workflow, particularly in primary care settings

  • Activity monitoring:

    • Studies examining the role of digital monitoring of activity on improvement of glycemia and other metabolic parameters in PWD

  • Digital nutritional monitoring

    • The use of mobile applications to facilitate measures of macronutrient content of meals in PWD, and the impact of these interventions on diabetes-specific outcomes.

  • Telemedicine, directed text messaging, patient portals, and peer-support

    • Studies assessing the incorporation of virtual communication into a multimodality virtual diabetes clinic model

    • Studies examining the influence of digital methods of multi-touchpoint peer support on glycemic and non-glycemic diabetes-specific outcomes

  • Gaming and gamification

    • Studies examining the effect of digital gamification on the uptake and sustained adoption of diabetes education to improve knowledge and promote self-care behaviors (dietary, activity, and medication adherence) in a manner that improves diabetes-specific outcomes

  • DHT adoption and sustainment

    • Studies examining factors predicting and improving patient engagement, adoption, and sustained use and utility of DHT interventions in PWD, and phenotyping according to acceptance of different modalities of DHT (CGM, wearables, telehealth, etc.) 

    • Studies examining the role of interventions to improve access of DHT for all PWD; to evaluate, measure, and improve digital literacy; and examine the influence of health beliefs and trust in the HCS on the successful utilization of all forms of DHT, including telemedicine 

    • Studies examining the influence of DHT interventions on patient engagement, self-empowerment, diabetes distress, and quality of life using validated measures.

    • Studies including a specific aim to determine the cost-effectiveness of specific DHT interventions in PWD 

    • Studies examining the effect of incentivizing PWD, providers and the health care system to incorporate DHT into diabetes management 

    • Studies examining the role of digital health navigators, including AI-based systems, in improving the acceptability and sustainability digital health interventions in PWD 

Are there any additional benefits I would receive?

  • Potential to position your digital health intervention for future large multicenter effectiveness studies if early clinical evidence is strong.

  • Grant support includes access to NIH peer review and scientific oversight.

Note: There’s no letter of intent required.

What is the timeline to apply and when would I receive funding?

Posted Date: September 17, 2025

Application Due: October 6, 2026 by 5:00 PM local time

Where does this funding come from?

NIH — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the U.S. Department of Health and Human Services.

CFDA: 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research.

Who is eligible to apply?

Eligible domestic applicants include:

  • Higher education institutions (public/private)

  • Nonprofits (with or without 501(c)(3) status)

  • For-profit organizations (including small businesses)

  • Local and state governments

  • Tribal governments/organizations

  • Public housing authorities

  • Independent school districts

  • U.S. Federal agencies are eligible

Foreign organizations are NOT eligible.

What companies and projects are likely to win?

Strong proposals will have:

  • A clearly defined clinical trial plan with measurable outcomes.

  • Meaningful patient, provider, and community engagement integrated into design and implementation.

  • Digital interventions that are ready for testing, not just conceptual.

  • Evidence of feasibility and mechanism for adoption in real-world settings.

Are there any restrictions I should know about?

Not responsive:

  • Projects developing new digital devices or algorithms.

  • Studies focused on automated insulin delivery, artificial pancreas, or hybrid closed-loop tech.

  • Research using DHT data only for subtyping/classification.

  • Mechanistic trials that are not testing an intervention’s effectiveness.

How long will it take me to prepare an application?

Typical NIH R01 applications take several months to:

  • Develop a rigorous clinical trial design,

  • Form research team + collaborations,

  • Draft research strategy + human subjects sections,

  • Complete registrations (SAM, eRA Commons).

Most institutions begin 6-12 months before due date.

How can BW&CO help?

BW&CO can assist with:

  • Translating this technical RFA into a clinical trial proposal roadmap.

  • Crafting aims, hypotheses, and outcomes tables tailored to NIH review criteria.

  • Aligning digital intervention strengths with NIH priorities.

  • Supporting human subjects/clinical trial documentation and compliance.

How much would BW&CO Charge?

We have both fractional engagements ($250 an hour) and full engagements ($13,000 + 5%) available.

Additional Resources

Review the solicitation here.

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Pennsylvania Agricultural Innovation Grant Program

Deadline: April 18, 2026

Funding Award Size: $7500 - $2 million

Description: Apply by 11:59 PM ET on April 18, 2026. Pennsylvania’s $10M Agricultural Innovation Grant offers up to $2M for farm technology, energy, and sustainability projects.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

Deadline Approaching: Apply by 11:59 PM ET on April 18, 2026 — this competitive state grant is now open and closing soon. The Pennsylvania Agricultural Innovation Grant Program offers a $10 million investment to help farmers, agricultural businesses, and innovators deploy new technologies, improve sustainability, and scale solutions that enhance production, conservation, and energy efficiency statewide. Applications must be submitted online via the Single Application for Assistance between 8 AM ET Feb 2, 2026 and 11:59 PM ET April 18, 2026.

How much funding would I receive?

Total funding available: $10 million in the 2025–26 round.

Grant types & award sizes:

  • Innovation Planning Project Grant: $7,500–$50,000 (30% non-state match required)

  • Onsite Project Grant: $5,000–$200,000 (50% non-state match required)

  • Regional Impact Project Grant: $100,000–$2,000,000 (50% non-state match required; must benefit ≥2 eligible persons/businesses)

What could I use the funding for?

Funding reimburses project planning, implementation, and regional impact innovations in the following priority areas:

Key eligible innovation areas:

  • Improve energy efficiency and water quality on farms

  • Reduce water use, odors, or solid waste

  • Improve production, processing, commercialization, or utilization of agricultural commodities

  • Produce energy from manure, food waste, biomass

  • Deploy low-carbon or no-carbon energy equipment

  • Farm management technologies (e.g., diagnostics, data tools)

  • Process efficiency tools (sorting, grading, etc.)

  • Biosecurity and plant/animal health innovations

  • Cybersecurity and data analytics solutions

Are there any additional benefits I would receive?

Beyond direct funding, grantees will:

  • Gain credibility and visibility as part of Pennsylvania’s nation-leading innovation portfolio

  • Support broader economic growth and sustainability across the Commonwealth’s agricultural sector

  • Build proof points to attract follow-on investment and partners

What is the timeline to apply and when would I receive funding?

Application window:

  • Opens: 8 AM ET, February 2, 2026

  • Closes: 11:59 PM ET, April 18, 2026
    Applications must be submitted online through the Single Application for Assistance system; late submissions will not be reviewed.

Funding decisions and reimbursement timelines depend on PDA’s review process and grant execution, typically following award announcements after April 2026.

Where does this funding come from?

Funding is part of the Commonwealth of Pennsylvania’s 2025–26 budget under the Shapiro Administration, investing $10 million in the second round of the nation’s first Agricultural Innovation Grant Program to strengthen farm sustainability, technology adoption, and clean energy development.

Who is eligible to apply?

Eligible applicants include:

  • Individuals who grow an agricultural commodity with anticipated sales of > $2,000/year

  • Individuals who process an agricultural commodity with anticipated sales of > $10,000/year

  • Providers of technical services to farmers (e.g., conservation, veterinary care, engineering, farm management)

  • Persons or cooperative associations that use agricultural commodities to create products or energy

What companies and projects are likely to win?

Competitive proposals will:

  • Clearly align with innovation priority areas outlined above

  • Demonstrate measurable impact (economic, environmental, technological)

  • Include strong budgets, timelines, and success metrics

  • Show scalable and practical outcomes for Pennsylvania agriculture

Projects with broad applicability (e.g., renewable energy systems, advanced processing technologies, farm-scale data tools) and those that deliver regional benefits are especially strong candidates.

Are there any restrictions I should know about?

Applicants must:

  • Use non-state matching funds at required levels

  • Submit paid receipts for reimbursement requests

  • Ensure projects are located in Pennsylvania and comply with all state laws and regulations

  • Only costs incurred during the contract period are eligible for reimbursement

How long will it take me to prepare an application?

Preparation time depends on project complexity:

  • Simple planning projects: 1–3 weeks

  • Onsite and regional projects with detailed budgets and partners: 2–6+ weeks
    You must gather narratives, budgets, metrics, match commitments, and letters of support before the April 18 deadline.

How can BW&CO help?

BW&CO can assist by:

  • Translating your innovation idea into a compelling application narrative

  • Structuring budgets and measurable outcomes to meet PDA criteria

  • Identifying matching fund strategies and partner letters

  • Reviewing drafts for clarity, cohesion, and competitiveness

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

ARPA-H SSO: “AGENTIC AI-ENABLED CARDIOVASCULAR CARE TRANSFORMATION” (ADVOCATE)

Deadline: February 27, 2026

Funding Award Size: $1 million - $50 million

Description: ARPA-H ADVOCATE funds agentic AI for cardiovascular care, including FDA-regulated clinical AI agents, supervisory AI, and health system deployment.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

ARPA-H is now accepting proposals for ADVOCATE: Agentic AI-Enabled Cardiovascular Care Transformation, a major new Innovative Solutions Opening (ISO) focused on deploying autonomous, FDA-regulated clinical AI agents for cardiovascular disease (CVD) care at national scale.

This program is designed to fund teams that can build, validate, and deploy patient-facing AI agents, paired with independent supervisory AI, and integrate them directly into real healthcare systems. Selected performers will work closely with FDA, large health systems, and ARPA-H leadership to establish a blueprint for scalable, reimbursable agentic AI in healthcare. A Solution Summary is mandatory and is due February 27, 2026, at 5:00 PM EST. Full proposals are by invitation only and are due April 1, 2026, at 5:00 PM EST.

How much funding would I receive?

  • Total award size: Not specified in the solicitation

  • Number of awards: Multiple awards anticipated

  • Funding mechanism: Other Transaction (OT) Agreements

  • Program length: Up to 39 months

    • Phase 1A: 12 months

    • Phase 1B: 12 months (option)

    • Phase 2: 15 months (option)

What could I use the funding for?

Funding must support development, validation, and deployment of agentic AI systems for cardiovascular care, aligned to one or more of the following Technical Areas (TAs):

TA1 — CVD Agent (Patient-Facing Clinical AI)

  • Autonomous or semi-autonomous AI agents that:

    • Provide diagnostic and treatment assistance

    • Adjust prescriptions for CV conditions (FDA medical device)

    • Integrate real-time EHR and wearable data

    • Deliver 24/7 outpatient care management

  • Clinical reasoning using multimodal inputs (text, voice, image, video)

  • FDA regulatory engagement and authorization

  • Deployment into real health systems for scalability studies

TA2 — Supervisory Agent (AI Oversight & Control)

  • Disease-agnostic AI that:

    • Monitors safety, accuracy, uncertainty, and risk of clinical AI

    • Enables real-time control and auditability

    • Supports FDA Medical Device Development Tool (MDDT) qualification

  • Continuous post-market monitoring functionality

  • Strong preference for open-source solutions

TA3 — Scaled Implementation (Health Systems Only)

  • Integration of TA1 and TA2 agents into live clinical workflows

  • Access to EHR production and pre-production environments

  • Execution of large-scale Scalability Studies

  • Clinical outcome, cost, and reimbursement evidence generation

Are there any additional benefits I would receive?

Selected teams receive:

  • Direct engagement with FDA throughout development

  • Access to real EHR data, clinicians, and patients (via TA3 performers)

  • Participation in large, ARPA-H-funded scalability studies

  • Validation by an independent IV&V partner

  • Visibility with payers and CMS-relevant evidence generation

  • Potential facilitation of investor engagement by ARPA-H

What is the timeline to apply and when would I receive funding?

Key dates (firm):

  • Posting date: January 13, 2026

  • Proposers’ Day: January 23, 2026 (8:30 AM – 5:00 PM EST)

  • Proposers’ Day registration deadline:

    • In-person: January 21, 2026, at 5:00 PM EST

    • Virtual: January 21, 2026, at 5:00 PM EST

  • Solution Summary due: February 27, 2026, at 5:00 PM EST

  • Full proposal due (if invited): April 1, 2026, at 5:00 PM EST

Funding timing after submission is not specified and is contingent on negotiations and down-selection decisions.

Where does this funding come from?

  • Agency: Advanced Research Projects Agency for Health (ARPA-H)

  • Office: Scalable Solutions Office (SSO)

  • Authority: Other Transaction (OT)

Who is eligible to apply?

Eligible applicants include:

  • U.S. startups and growth-stage companies

  • Universities and academic teams

  • Non-profit organizations

  • Non-federal research organizations

Not eligible:

  • Federally Funded Research and Development Centers (FFRDCs)

  • Federal government entities or employees (as performers)

  • Entities from covered foreign countries or foreign entities of concern

  • Organizations with unmitigable ARPA-H conflicts of interest

TA3 applicants cannot apply to TA1 or TA2.

What companies and projects are likely to win?

ARPA-H is explicitly seeking teams that:

  • Are building agentic (not rules-based) clinical AI

  • Can meet FDA medical device or MDDT requirements

  • Have real experience integrating with EHRs and health systems

  • Can demonstrate a path to non-inferiority vs cardiologists

  • Are prepared for open data sharing and multi-party collaboration

  • Can scale beyond pilots into national deployment

Incremental clinical decision support tools are unlikely to be competitive.

Are there any restrictions I should know about?

Key restrictions include:

  • Foundation models cannot be developed from scratch

  • Solutions must be interoperable with other agents

  • Clinical AI must pursue FDA authorization or qualification

  • Extensive data-sharing and collaboration are mandatory

  • Foreign talent, ownership, or funding risks are heavily scrutinized

  • TA1 and TA2 proposals must remain technically independent

How long will it take me to prepare an application?

  • Solution Summary: ~2–4 weeks for competitive teams

  • Full Proposal: ~6–10 weeks if invited

Team formation, regulatory strategy, and data architecture must be addressed early.

How can BW&CO help?

BW&CO helps teams:

  • Translate ADVOCATE requirements into a clear, fundable narrative

  • Position technical capabilities against TA-specific metrics

  • Shape FDA and commercialization strategy language

  • Design compliant multi-party teaming structures

  • Avoid common ARPA-H disqualifiers

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Development of Radiological/Nuclear Medical Countermeasures (MCMs) And Biodosimetry Devices

Deadline: May 04, 2026

Funding Award Size: $500k to $2 million

Description: NIH NIAID seeks proposals for radiological/nuclear medical countermeasures or biodosimetry devices. Proposals due May 4, 2026 at 3:00 PM ET.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The National Institute of Allergy and Infectious Diseases (NIAID) is actively seeking proposals to develop radiological/nuclear medical countermeasures (MCMs) or biodosimetry biomarkers and devices to support response to a radiological or nuclear public health emergency. This is a cost-reimbursement contract opportunity, not a grant, and is intended to advance technologies that reduce mortality, guide triage, and improve treatment decisions after radiation exposure. Proposals are due May 4th, 2026.

How much funding would I receive?

  • Total contract value: Not specified (listed as “TBD” in the solicitation)

  • Contract type: Cost-reimbursement with fixed fee

  • Base period funding: TBD

  • Option periods: Up to two option periods, funding TBD

Because dollar amounts are not pre-set, funding levels will depend on scope, cost realism, and negotiation with NIAID.

What could I use the funding for?

Funding must support one of the two objectives below.

A. Radiological/Nuclear Medical Countermeasures (MCMs)

Funding may be used to develop safe and effective MCMs that:

  • Mitigate and/or treat normal tissue injuries caused by ionizing radiation

  • Reduce radiation-associated mortality or major morbidities

  • Are efficacious 24 hours or later post-exposure (MCMs intended for immediate post-exposure use are generally excluded, unless otherwise noted in the objectives)

B. Biodosimetry Biomarkers and Devices

Funding may be used to advance biodosimetry biomarkers and/or devices that:

  • Inform triage and treatment strategies

  • Are suitable for use during a radiation public health emergency

Allowable Cost Categories (with Contracting Officer approval where required) include:

  • Personnel and research labor

  • Subcontracts and consultants

  • Travel (including foreign travel)

  • Patient care costs

  • Equipment and materials

  • Printing and reporting

  • Research-related conferences and meetings

Are there any additional benefits I would receive?

In addition to funding, awardees receive:

  • A direct contractual relationship with NIH/NIAID

  • Eligibility for option period extensions at the government’s discretion

  • The ability to generate patents, subject to federal invention regulations

  • Increased credibility for future BARDA, NIH, and DoD opportunities

What is the timeline to apply and when would I receive funding?

  • Solicitation issued: February 10, 2026

  • Questions due: March 3, 2026 (recommended)

  • Proposal deadline: May 4, 2026 at 3:00 PM ET

  • Contract period of performance: TBD

  • Funding start: After award and contract execution (date not specified)on maturity or need

Where does this funding come from?

This funding is provided by the National Institute of Allergy and Infectious Diseases (NIAID) within the National Institutes of Health (NIH), U.S. Department of Health and Human Services.

Who is eligible to apply?

Eligible applicants include:

  • For-profit companies

  • Small businesses

  • Nonprofits and research institutions

  • Universities

  • Domestic and foreign entities

Applicants must be registered in SAM prior to award.

What companies and projects are likely to win?

NIAID is looking for teams that:

  • Have strong scientific and technical rationale

  • Address clearly defined unmet needs in radiation response

  • Can demonstrate feasible development and execution plans

  • Align tightly with the Research and Technical Objectives in the solicitation

Projects are evaluated primarily on technical merit, relevance to agency priorities, and availability of funds.

Are there any restrictions I should know about?

Key restrictions include:

  • You may only submit one focus per proposal (MCM or biodosimetry)

  • Certain costs require prior Contracting Officer approval

  • Strict compliance with human subjects, animal welfare, data sharing, and publication policies

  • Funds may not be used for prohibited activities (e.g., abortion, human embryo research, needle exchange, promotion of controlled substances legalization)

How long will it take me to prepare an application?

Most companies should plan for 8–12+ weeks to prepare:

  • A full technical proposal and Statement of Work

  • A detailed cost proposal and supporting documentation

  • Required representations, certifications, and attachments

How can BW&CO help?

BW&CO can:

  • Translate the BAA into a clear win strategy

  • Define scope, milestones, and budget that survive NIH negotiation

  • Draft or review the technical and business proposals

  • Ensure compliance with NIH contract requirements

  • Position your company for option periods and follow-on funding

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Air Force Cryptologic Office (AFCO) Commercial Solutions Opening (CSO)

Deadline: September 30, 2026

Funding Award Size: $50k to $50 million

Description: Apply for the Air Force Cryptologic Office (AFCO) Commercial Solutions Opening. Rolling submissions, awards from $50K–$50M for EW, AI, IO, and multi-domain defense technologies.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The Air Force Cryptologic Office (AFCO) is actively seeking innovative commercial technologies to support U.S. Air Force cyberspace intelligence, electromagnetic warfare, information operations, and multi-domain operations. This Commercial Solutions Opening (CSO) is designed to move fast, fund mature technologies applied in novel ways, and support field demonstrations—ideally within one year.

How much funding would I receive?

AFCO expects to make individual awards ranging from:

  • $50,000 to $50,000,000 over the full period of performance

These amounts are not strict limits. Proposals over $15,000,000 must include phased options that allow for incremental funding. All awards are subject to the availability of funds.

What could I use the funding for?

Funding may be used to develop, demonstrate, test, or deploy innovative commercial technologies aligned with AFCO’s mission areas. Proposals must address one or more of the following capability areas:

AFCO-CM-001, ELECTROMAGNETIC WARFARE (EW)

  • Electromagnetic attack, support, and protection

  • EW data fusion and advanced signal processing

  • Cognitive EW and AI/ML-enabled techniques

  • EW battle management and waveform generation

AFCO-CM-002, INFORMATION OPERATIONS (IO)

  • Technologies that affect adversary decision-making

  • Capabilities targeting informational, physical, or cognitive dimensions

  • Generative AI or autonomous AI applied to the information environment

AFCO-CM-003, Electromagnetic Digital Communications

  • Free-space and space-based digital communications

  • Access, denial, disruption, degradation, deception, or destruction of communications

  • Novel approaches emphasizing extensibility over single-purpose solutions

AFCO-CM-004, Multi-Domain Innovation

  • Integrated effects across EW, cyberspace, ISR, and information operations

  • Automated and synchronized multi-domain operational capabilities

Are there any additional benefits I would receive?

In addition to funding, successful companies may receive:

  • Direct engagement with Air Force technical and operational stakeholders

  • Opportunities for follow-on contracts or Other Transactions (OTs)

  • Potential multi-year periods of performance (up to five years)

  • A clear pathway from prototype to operational relevancest Proposal and SOW).

What is the timeline to apply and when would I receive funding?

  • Phase I: Quad Chart and White Paper may be submitted at any time before September 30, 2026

  • Phase II: Only by invitation from the Contracting Officer

  • Proposal preparation window (Phase II): 30 calendar days from invitation

  • Expected contract start: Approximately 90 days after proposal submission

Period of performance:

  • Typically 1–5 years, with exceptions considered based on maturity or need

Where does this funding come from?

Funding is provided by the Air Force Cryptologic Office (AFCO), Cyberspace ISR and Multi-Domain Innovation Division, under the U.S. Department of the Air Force.

Awards may be issued as:

  • Firm Fixed Price (FFP) contracts

  • Fixed Price Incentive (FPI) contracts

  • Other Transactions (OTs) under 10 U.S.C. §2371bal Medicines).

Who is eligible to apply?

Eligible applicants include:

  • U.S.-based commercial companies

  • Small businesses and non-traditional defense contractors

  • Companies offering commercial items, technologies, or services

To receive an award, companies must:

  • Be registered in SAM.gov

  • Be considered responsible under FAR Part 9.1

  • Meet any security clearance requirements if proposing classified work

What companies and projects are likely to win?

Successful proposals typically:

  • Apply mature technologies in novel ways

  • Demonstrate clear relevance to AFCO mission needs

  • Support field demonstrations within one year (ideally)

  • Offer measurable improvements to operational effectiveness

  • Align with open architecture approaches (e.g., SOSA, OMS/UCI, modular software/hardware)

Are there any restrictions I should know about?

Yes. Key restrictions include:

  • All submissions must be commercial solutions

  • Classified submissions require prior coordination

  • Proposals exceeding page limits will not be evaluated

  • Intellectual property assertions must follow DFARS requirements

  • AFCO may partially fund, incrementally fund, or decline any proposal

How long will it take me to prepare an application?

Typical preparation times:

  • Phase I (Quad Chart + White Paper): 1–3 weeks

  • Phase II (if invited): 30 calendar days

The Phase II submission includes a technical proposal, statement of work, and detailed pricing.

How can BW&CO help?

BW&CO can help you:

  • Rapidly assess fit against AFCO’s priority areas

  • Shape your Quad Chart and White Paper for evaluator clarity

  • Position your technology for Phase II invitation

  • Translate technical capabilities into mission-aligned value propositions

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Production of Drug Substances and Drug Products at Commercial Scale: Anti-Microbials and Large Volume Parenterals

Deadline: March 9, 2026

Funding Award Size: $250k to $10 million

Description: This BARDA BioMaP solicitation funds U.S.-based manufacturing projects that can scale antimicrobials and large volume parenterals to population-level production within 24 months. Deadline: March 9, 2026.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

BARDA (through the BioMaP-Consortium) is looking to fund commercial-scale (“population scale”) domestic production of at least one (1) key starting material (KSM), drug substance, and/or drug product—with a stated preference for Anti-Microbials and Large Volume Parenterals (LVPs). This is an Enhanced White Paper solicitation, and the deadline is March 9, 2026, 1:00 PM ET (late submissions may not be evaluated).

How much funding would I receive?

  • Total estimated funding (all projects): approximately $200 million (subject to availability and adjustment).

  • Award size per project is not specified in the RPP.

  • The Government anticipates making multiple awards and also reserves the right to make one, multiple, or no awards.

What could I use the funding for?

Below are the uses that map directly to the RPP’s objectives and deliverables.

1) Objective A: Engineering design + study phase (design/refine the approach)

You can propose work to design and refine an end-to-end, scalable manufacturing concept that supports population-scale production, including:

  • Select at least 1 target drug substance jointly with the Government (minimum entry: MRL 6), including selection rationale.

  • Build a detailed list of molecules/molecule classes, required materials, systems, and equipment across manufacturing phases.

  • Develop and refine an analytical/characterization and manufacturing plan for population-scale production with automated and integrated processes across design, manufacturing, testing, and analysis—intended to increase MRL to 10 and meet U.S. Pharmacopeia standards and ICH guidelines for purity, potency, safety, validation, quality, etc.

  • Include an infrastructure governance framework (management structure, partnerships, scheduling considerations).

  • Assess domestic market maturity and conduct a risk assessment of domestic capabilities.

  • Present Objective A results and a plan for Objective B for Government approval to proceed.

2) Objective B: Demonstrate the model + population-scale manufacturing

If approved to proceed after Objective A, you can propose to:

  • Develop and execute an analytical model and demonstrate manufacturing of a KSM/API progressing from MRL 6/7 to MRL 10, in compliance with USP and ICH expectations.

  • Run multiple scenarios/production runs to test assumptions and identify conditions that improve or worsen:

    • Shortest time to market

    • Lowest development/deployment costs

    • Optimal time-to-market with cost tradeoffs

    • Key drivers of time and cost

    • Recommendations for future investment to enable population-scale production in real markets

  • Produce required program outputs (e.g., technical batch reports, final technical report with variables/assumptions/model runs).

  • The RPP also lists deliverables tied to drug products, including registration batches, completion of environmental/engineering/registration batch runs, and ANDA filings for each drug product (as applicable to your scope).

3) Program management + risk + schedule deliverables

You can include work to:

  • Manage the full program (integration, coordination, milestone schedule, critical path, go/no-go criteria).

  • Maintain a risk register and report risk changes.

  • Deliver required monthly technical progress reports and other specified deliverables.

4) Domestic industrial base / capacity expansion (U.S. soil)

The RPP states proposals are expected to be focused on United States investments, and capacity expansion work must be executed within the continental U.S. and its Territories (even for overseas-based companies).

Are there any additional benefits I would receive?

  • This is under BARDA’s BioMaP-Consortium OTA vehicle (OTA Number 75A50123D00003) and executed via Project Agreements under the consortium framework.

  • Proposals rated Acceptable through Excellent but not immediately funded may be placed into an electronic “Basket” for up to 2 years, remaining eligible for award during that time (if funding becomes available and after review of a Full Cost Proposal and SOW).

What is the timeline to apply and when would I receive funding?

Key solicitation dates

  • RPP Issue Date: February 6, 2026

  • Virtual Teaming Speed Networking Event: February 12, 2026

  • Questions due: February 18, 2026 (by 1:00 PM ET) (submit via email to biomap-contracts@ati.org)

  • Enhanced White Papers due: March 9, 2026 (by 1:00 PM ET)

Award / performance timing

  • Anticipated Period of Performance: not to exceed 24 months.

  • Offerors should plan for PoP to begin in Quarter 3 of Government Fiscal Year 2026 (Government may change start date via negotiations).

Where does this funding come from?

  • Strategic oversight is provided by BARDA.

  • The RPP references program interests from:

    • ASPR IBMSC Office (Advanced Manufacturing Domain)

    • HHS Defense Production Act (DPA) Title III Program (with preference for projects strengthening security of supply for items on the FDA List of Essential Medicines).

Who is eligible to apply?

Minimum eligibility criteria (must meet):

  • You must be a BioMaP-Consortium member prior to award of a Project Agreement.

  • You must show demonstrated experience in scalable manufacturing of KSMs/APIs and finished product form drugs, specifically at or beyond MRL 6.

  • Cost share is required to be eligible (must describe amount, whether cash or in-kind, and valuation method).

What companies and projects are likely to win?

Based on the stated evaluation factors and technical objectives, the strongest submissions will typically be those that:

  • Propose a credible path to population-scale production (hundreds of millions of doses) with domestic production capacity.

  • Clearly align to the preference area: Anti-Microbials and Large Volume Parenterals.

  • Demonstrate capability to move from MRL 6/7 to MRL 10 with strong USP/ICH-aligned quality/compliance planning.

  • Present an integrated approach (automation, analytics, validation/QC, supply chain, and governance) with clear milestones and risk controls.

  • Show meaningful, well-supported cost share.

  • Bring a multidisciplinary team with relevant industrial execution experience, and (encouraged) small business utilization.

Are there any restrictions I should know about?

Yes—several are explicit:

  • Submission method: Enhanced White Papers must be submitted online via BIDS; no other submission methods accepted.

  • Deadline enforcement: Late Enhanced White Papers may not be evaluated.

  • Format limits: Enhanced White Paper maximum 15 pages (excluding cover page and specified appendices); mandatory template/headers required.

  • Domestic expansion requirement: Capacity expansion work must be executed within the continental U.S. and its Territories (per Base Agreement requirement referenced in the RPP).

  • DPA domestic source compliance: Offeror must be compliant with the DPA definition of a “domestic source” (50 U.S.C. 4552(7)).

  • Regulatory compliance: Expected compliance with relevant FDA, DEA, USP and cGMP practices.

  • Salary rate limitation: Direct salary above Federal Executive Schedule Level II is unallowable under the OTA.

  • SAM.gov / UEI: A UEI from SAM.gov is required prior to award.

  • Security requirements: Attachment B lists ASPR deliverables and security requirements that may be required for resulting projects.

How long will it take me to prepare an application?

What the RPP requires:

  • A compliant Enhanced White Paper using the mandatory template (plus required appendices).

  • Enough detail to be evaluated on Technical Approach/Solution, Relevant Experience, and a Cost/Price ROM estimate.

  • A clearly described cost share package (required for eligibility).

  • A credible timeline that addresses the stated Schedule Objectives (Objective A and Objective B planning within a total PoP ≤ 24 months).

Practically, teams that are already organized and have MRL 6+ manufacturing readiness typically need to pull: technical narrative, milestones, ROM build-up, teaming roles, and cost share substantiation—plus ensure consortium membership is in place prior to award.

How can BW&CO help?

BW&CO can support you by turning this RPP into a submission-ready package, including:

  • A compliance-driven Enhanced White Paper outline and draft aligned to Attachment A headers

  • A reviewer-style gap check against eligibility requirements (MRL, consortium membership timing, domestic source, cost share)

  • A strong Objective A/Objective B story with measurable milestones and deliverable mapping

  • ROM narrative support (assumptions, labor categories, subcontractor framing) and cost share packaging

  • Final “red team” editing for clarity and evaluator alignment.

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

National Defense Stockpile (NDS) Research & Qualification BAA – DLA

Deadline: Submit White Paper ASAP

Funding Award Size: $250k to $10 million

Description: Funding for research, development, and qualification of strategic and critical materials to strengthen domestic supply chains and support Department of Defense requirements.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The Defense Logistics Agency (DLA) Strategic Materials office is seeking white papers under its National Defense Stockpile (NDS) Research and Qualification Broad Agency Announcement to fund research, development, and qualification of strategic and critical materials that strengthen domestic supply chains. Awards may support early-stage research through higher-TRL qualification efforts, with individual awards up to $10 million. The BAA is open from January 30, 2026 through January 30, 2029, with white papers due no later than May 1, 2028.

How much funding would I receive?

Individual awards are expected to range from relatively small research efforts up to $10,000,000 per award, with multiple smaller awards more likely than a single large award. Phase I efforts are limited to the Simplified Acquisition Threshold ($250K) and up to 12 months, while Phase II efforts may be funded for up to $10 million with periods of performance up to 24 months.

What could I use the funding for?

Funding may be used for research, development, demonstration, and qualification activities related to strategic and critical materials according to the following priorities:

Priority 1: Antimony, Bismuth, Gallium, Germanium, REEs and REE Magnet Materials

Priority 2: Graphite, Battery Materials, Magnesium, Refractory Metals, Energetics

Priority 3: ZOC and Related Materials, Indium, PGMs, Neon, Manganese

Priority 4: High Purity Aluminum, Beryllium, Cobalt, Scandium and Yttrium, Fluorspar


Areas of interest for the above materials are:

(1) Refining, Processing, and Beneficiation:

The research of, assessment of, evaluation of, development of, demonstration of, or establishment of:

(a) Processes to enhance the quality of materials, improve efficiency of production processes, refine or benefit from material, or mitigate recurring problems.

(b) Impacts of and solutions to external “bottlenecks” in raw material supply chains addressing materials that have been delayed, duration of the shortages, effect on production lead times, prices and impact on delivery of finished products.

(c) Impacts of and solutions to internal “bottlenecks” in materials refining processes related to converting feedstock into sellable product considering issues such as incorrect or inferior feedstock, equipment failures, lack of skilled work forces, etc.

(2) Recycling, Conservation and Substitution Options:

Identification of, evaluation of, developing methods for, and establishing domestic capabilities to:

(a) Material substitutes in active use by domestic and trade-friendly international processors and manufacturers; include limitations and common issues associated with use of the substitute material.

(b) Research to develop or qualify materials as acceptable substitutes including use of existing and emerging products.

(c) Recycling opportunities, including industrial infrastructure and logistical perceived limitations.

(d) Recycle and recover neodymium iron boron (NdFeB) or Samarium Cobalt (SmCo) magnets or recovery of rare earths or its alloys. The specifications should include the total rare earth metals (TREM) present in the recycled magnets. As well as identification of energy magnetic density of the recycled magnets.

(3) Qualification of Materials:

(a) Qualification of Research to Department of Defense Programs of Record. Projects will require letters of support from known DOD Programs of Record indicating intent to utilize the qualified material upon successful completion of the work.

Are there any additional benefits I would receive?

Beyond the formal contract award, there are meaningful indirect benefits to receiving a DLA Strategic Materials award:

  • Government Validation and Credibility: Selection signals technical merit and relevance to U.S. defense supply-chain priorities.

  • Stronger Position in Defense Supply Chains: Successful projects can lead to qualification for DoD Programs of Record, unlocking long-term procurement opportunities.

  • Nondilutive Technology Advancement: Companies can mature materials and processes without equity dilution.

  • Improved Exit and Acquisition Potential: Government-validated materials qualification can increase strategic value to primes and acquirers.

What is the timeline to apply and when would I receive funding?

The BAA is open from January 30, 2026 through January 30, 2029. White papers may be submitted on a rolling basis but must be received by May 1, 2028. White papers are evaluated as received, and selected offerors may be invited to submit full proposals. All evaluations cease on August 1, 2028, and awards must be made by September 15, 2028.

Where does this funding come from?

Funding is provided by the Defense Logistics Agency (DLA) Strategic Materials program under its authority to support the National Defense Stockpile and strengthen domestic strategic and critical materials supply chains.

Who is eligible to apply?

Any responsible domestic source capable of performing the required research may submit a white paper. Eligibility includes businesses, nonprofits, and educational institutions that are registered in SAM.gov. Foreign-owned firms may participate subject to foreign disclosure review. There is no set-aside for small businesses, though small and disadvantaged businesses are encouraged to participate.

What companies and projects are likely to win?

Successful proposals typically demonstrate:

  • Strong scientific and technical merit that improves strategic materials supply-chain resilience

  • Clear alignment with one or more stated Areas of Interest and listed strategic materials

  • Innovative, feasible, and non-duplicative technical approaches

  • Qualified teams with relevant facilities, experience, and past performance

  • Reasonable and realistic pricing supported by deliverables

Are there any restrictions I should know about?

White papers must be unclassified and may not contain proprietary information. A white paper submission is mandatory to be eligible for a full proposal. Projects are limited to a maximum of three years, depending on phase.

How long will it take me to prepare an application?

For first time applicants, white-papers will likely take 35 to 50 hours without BW&CO assistance.

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

  • Triple your likelihood of success through proven strategy and insider-aligned proposal development

  • Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

  • Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth under Federal & State R&D Initiatives.

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

DIU - Containerized Autonomous Drone Delivery System (CADDS)

Deadline: February 17, 2026 at 23:59:59 US/Eastern Time

Funding Award Size: $300K to $5M+

Description: Apply for DIU funding for containerized autonomous drone delivery systems. OT prototype contracts with DoD. Deadline Feb 17, 2026.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

DIU’s Commercial Solutions Opening (CSO) solicitation PROJ00637 — Containerized Autonomous Drone Delivery System (CADDS) seeks innovative commercial solutions to enable rapid deployment and autonomous operation of large numbers of unmanned aerial systems (UAS) from containerized platforms. This opportunity closes February 17, 2026 at 23:59:59 US Eastern Timeurgent submission recommended.

How much funding would I receive?

The exact award amount is not specified online. DIU typically awards prototype contracts under Other Transaction (OT) authority, with budgets determined during negotiation based on solution scope and DoD partner need. Follow-on production contracts may be possible if the prototype is successful.

What could I use the funding for?

This solicitation is looking for solutions that:

  • Enable rapid, large-scale UAS deployment from containerized platforms.

  • Automate storage, launch, recovery, and refit for multi-agent systems.

  • Provide rapid transport and emplacement using military/commercial vehicles.

  • Support resilient command and control interfaces and open architecture integration.

  • Reduce human operator burden and minimize required crew size.

You’d be expected to demonstrate capabilities within ~90 days of award.

Are there any additional benefits I would receive?

  • Potential follow-on production contracts without additional competition under 10 U.S.C. § 4022 if the prototype succeeds.

  • A fast-moving path into Department of Defense fielding and contracting.

What is the timeline to apply and when would I receive funding?

  • Proposal Deadline: February 17, 2026 @ 23:59:59 US/Eastern.

  • DIU typically reviews solution briefs first, then invites selected teams to pitch/submit full proposals (often within ~30 days).

  • Prototype projects are generally expected to be demonstrable within ~90 days of award.

Where does this funding come from?

DIU is part of the U.S. Department of Defense, focused on accelerating commercial tech adoption for defense applications. Funding is administered under Other Transaction (OT) authority — a flexible contracting approach outside traditional FAR rules.

Who is eligible to apply?

U.S. and international vendors are eligible to respond.

  1. To use an OT agreement, requirements of 10 U.S.C. § 4022 must be satisfied (e.g., contributions by nontraditional defense contractors, small business participants, or cost sharing).

What companies and projects are likely to win?

Competitive submissions will:

  • Clearly align with rapid autonomous UAS deployment at scale.

  • Demonstrate modularity, open architecture, and operational utility.

  • Show ability to reduce human operator burden and handle austere environments.

  • Present clear pathway to meet the ~90-day demonstration target.

Are there any restrictions I should know about?

Compliance with Section 889 of the John S. McCain NDAA is required for award.

  1. IP is generally retained by the company, with negotiated DoD use rights.

  2. OT agreements have specific cost-sharing and contractor status rules under 10 U.S.C. § 4022.

How long will it take me to prepare an application?

  • Solution briefs are typically ~5 pages (or ~15 slides) and can be prepared in 1–3 weeks with focused effort.

  • Full proposals (if invited) will require detailed technical and project execution plans.

How can BW&CO help?

BW&CO can assist with:

  • Crafting solution briefs that clearly align with DIU’s mission and review criteria.

  • Developing full OT proposals with technical, cost, and operational plans.

  • Strategizing for rapid prototype demonstration and DoD transition pathways.

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

DIU - Sensors and Seekers For Fire Control

Deadline: February 17, 2026 at 23:59:59 US/Eastern Time

Funding Award Size: $300K to $5M+

Description: Funding for development of advanced sensor and seeker systems for interceptor fire control against ballistic and hypersonic threats.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

Act now — Responses due February 13, 2026 at 23:59:59 US/Eastern for Deorbit as a Service, a high-priority Defense Innovation Unit (DIU) Commercial Solutions Opening (CSO) to solve a strategic orbital debris and space sustainability challenge. This solicitation funds scalable autonomous technologies that can deorbit unprepared satellites safely and reliably, reducing orbital congestion and enabling future space operations. This is a rare fast-paced opportunity to partner with the U.S. Department of Defense (DoD) using flexible Other Transaction Authority with potential follow-on production contracts without further competition — massive market potential.

You’ll submit a Solution Brief that directly addresses specific detection, tracking, and discrimination capabilities using commercial sensing technologies. If selected, DIU can award a Prototype Other Transaction (OT) agreement and potentially a follow-on production contract if the prototype is successful.

How much funding would I receive?

DIU does not publicly list a fixed award size on this solicitation page. Funding amounts for DIU prototype OT agreements vary based on technical scope and negotiated project budgets with selected vendors.

What could I use the funding for?

Funding may be used to develop and demonstrate prototypes that meet the Government’s technical needs, including:

A. Sensor System Development

  • LIDAR/LADAR, EO/IR, RF, or combined modalities that enable high-fidelity detection, tracking, and discrimination under extreme conditions.

B. Fire Control Enablement

  • Systems capable of providing real-time, fire-control-quality tracking data (range, angular resolution, update rates) for engagements against ICBMs or hypersonic glide vehicles.

C. Prototyping & Demonstrations

  • Bench-top or lab demonstrations within ~6–9 months.

  • On-orbit demonstrations as a hosted payload within ~12–24 months (if applicable).

Are there any additional benefits I would receive?

Yes. Commercial companies participating through DIU can gain:

  • Access to DoD customers and mission partners who care about real outcomes.

  • A potential follow-on production contract without a new competition after satisfactory prototype completion (per 10 U.S.C. §4022(f)).

  • Exposure to broader government adoption via Success Memos that other DoD entities can use.

What is the timeline to apply and when would I receive funding?

  • Application Deadline:
    🔹 February 17, 2026 at 23:59:59 US/Eastern Time

    Typical DIU CSO timeline:

    • Solution Brief submission → evaluation

    • ~30 days to get invited to pitch if selected

    • Contracts negotiated and awarded typically within ~60–90 days after selection (varies).

    Prototype execution milestones generally include lab demos within 6–9 months and potential on-orbit demos within 12–24 months, as outlined by this project.

Where does this funding come from?

The funding is provided through the Department of Defense (DoD) via the Defense Innovation Unit (DIU) using its Commercial Solutions Opening (CSO) process under Other Transaction (OT) Authority (10 U.S.C. 4022).

Who is eligible to apply?

U.S. and international vendors with relevant sensor and seeker technologies.

  • Companies must satisfy OT authority requirements per 10 U.S.C. 4022(d) (e.g., participation of nontraditional firms, small business involvement, or non-government funding share).

No specific size, revenue, or TRL ceiling is listed, but solutions must be technically relevant and commercially viable.

What companies and projects are likely to win?

Winners will propose solutions that demonstrate:

  • High-performance sensing and discrimination across threat scenarios.

  • Commercially scalable designs (design for manufacturability and low unit cost).

  • Plan for integration into aerospace or space platforms.

  • Capacity to meet aggressive prototyping timelines.

Companies offering modular, commercially producible systems that leverage dual-use technology trends have a competitive edge

Are there any restrictions I should know about?

Must comply with 10 USC 4022 OT authority requirements for award eligibility.

  • All submissions must certify no Controlled Unclassified Information (CUI) unless expressly allowed.

  • Awarded agreements will include compliance language for Section 889 of the 2019 NDAA.

How long will it take me to prepare an application?

Most DIU Solution Briefs are 5 pages or ~15 slides and should specifically address the challenge and key solution attributes. Preparation time depends on your level of readiness but planning 2–6 weeks to align technical, programmatic, and compliance content is reasonable.

How can BW&CO help?

BW&CO can support you to:

  • Translate DIU requirements into a winning Solution Brief that aligns with your tech and DoD’s need.

  • Craft compelling narrative for detection, tracking, and fire-control relevance.

  • Map technical milestones and prototyping costs for rapid award.

  • Prepare compliant attachments (e.g., SAM/SAM.gov, CAGE, IP/Section 889 compliance).

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

DIU - Deorbit as a Service

Deadline: February 13, 2026 at 23:59:59 US/Eastern

Funding Award Size: $300K to $5M+

Description: Funding for autonomous satellite deorbit, space sustainability, rendezvous & proximity operations

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

Act now — Responses due February 13, 2026 at 23:59:59 US/Eastern for Deorbit as a Service, a high-priority Defense Innovation Unit (DIU) Commercial Solutions Opening (CSO) to solve a strategic orbital debris and space sustainability challenge. This solicitation funds scalable autonomous technologies that can deorbit unprepared satellites safely and reliably, reducing orbital congestion and enabling future space operations. This is a rare fast-paced opportunity to partner with the U.S. Department of Defense (DoD) using flexible Other Transaction Authority with potential follow-on production contracts without further competition — massive market potential.

How much funding would I receive?

The BAA does not specify a fixed award size; funding will depend on DIU’s evaluation and negotiation of selected prototypes under the CSO. Awards are issued as Prototype Other Transaction (OT) agreements and can scale into larger production contracts if prototypes meet performance milestones.

What could I use the funding for?

This funding is intended to support:

  • Development of scalable deorbit systems (hardware + software).

  • Rapid prototyping and integrated testing within 18–24 months.

  • Safety & CONOPS development for rendezvous, proximity ops, and deorbit.

  • Risk-mitigation engineering for non-cooperative satellite interaction.

  • Commercial-ready production and launch planning.

Are there any additional benefits I would receive?

Yes — strategic advantages include:

  • Fast DIU prototype contracting using Other Transaction Authority.

  • Potential for follow-on production contracts without a new competitive process upon successful prototype completion.

  • Direct DoD engagement and visibility.

  • Entry into the defense space ecosystem with future technology transition opportunities.

What is the timeline to apply and when would I receive funding?

  • Application Deadline: February 13, 2026 at 23:59:59 US/Eastern — no extensions guaranteed.

  • Phase 1 Evaluation: Review of Solution Briefs.

  • Phase 2 (if selected): Pitch & potential invitation to full proposal.

  • Prototype Award: Typically within weeks/months after Phase 2 selection.

  • Prototype Delivery: 18–24 months expected.

Where does this funding come from?

Funding is provided through the Defense Innovation Unit (DIU) under the DoD’s Commercial Solutions Opening (CSO) process, using Other Transaction Authority (OTA) that enables rapid non-FAR contracting to prototype commercial solutions relevant to national security.

Who is eligible to apply?

U.S. and international companies can submit.

  1. Must satisfy 10 USC §4022(d) conditions for OT eligibility: significant nontraditional contribution or required small business participation, or non-government cost share.

  2. Companies without a CAGE code must register in SAM.gov early.

What companies and projects are likely to win?

Solutions that demonstrate:

  • System-level capability for autonomous deorbit operations.

  • Proven hardware + software maturity suitable for prototyping/launch.

  • Clear safety and fault-management plans.

  • Commercial scalability and cost-efficient operations.

  • Collaborative readiness with government and commercial partners.

Are there any restrictions I should know about?

Your Solution Brief must be PDF, ≤10MB with recommended ~5 pages or ~15 slides.

  1. Data must not exceed Controlled Unclassified Information unless certified.

  2. Must comply with Section 889 of the FY2019 NDAA (restricting certain telecom equipment).

How long will it take me to prepare an application?

Preparation time varies by team readiness:

  • Fast track: 1–2 weeks with existing conceptual materials.

  • Full brief + detailed CONOPS: 3–6+ weeks if ramping from scratch.

Given the February 13 deadline, start now — opportunities like this are rare and high impact.

How can BW&CO help?

BW&CO can:

  • Convert your technology narrative into a winning Solution Brief tailored for DIU evaluation criteria.

  • Advise on risk mitigation, CONOPS articulation, and transition planning to increase award likelihood.

  • Support teaming strategies with complementary partners to bolster competitiveness.

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Installation Energy & Water - Environmental Security Technology Certification Program (ESTCP)

Deadline: March 26, 2026

Funding Award Size: $300K to $5M+

Description: Funding for demonstration and validation of mature energy, water, cybersecurity, and building technologies that improve resilience, efficiency, and mission assurance at DoD installations.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The Environmental Security Technology Certification Program (ESTCP) is soliciting pre-proposals for FY 2027 to fund formal demonstrations of innovative Installation Energy & Water technologies. ESTCP supports mature technologies that improve energy resilience, water resilience, cybersecurity, and building performance at DoD installations through real-world demonstrations conducted at DoD facilities. Pre-proposals are due March 26, 2026 at 2:00 p.m. ET.

How much funding would I receive?

ESTCP awards typically support multi-year demonstration projects funded through cost-type or firm fixed-price contracts. While individual award sizes are not specified in the solicitation, projects commonly range from hundreds of thousands to several million dollars, depending on scope, duration, and demonstration scale.

What could I use the funding for?

Funding may be used to demonstrate and validate innovative technologies in one of the following ESTCP FY 2027 Installation Energy & Water Topic Areas:

Improve Energy Resilience with Long-Duration Energy Storage
This topic area seeks demonstrations of Long Duration Energy Storage (LDES) technologies integrated into military microgrids to meet the DoD’s requirement to power critical loads for 14 days during a grid outage. Technologies of interest include electrochemical, chemical, thermal, subsurface, and other LDES approaches, evaluated through Hardware-in-the-Loop (HIL) testing. The focus is on reducing or eliminating reliance on diesel fuel while improving lifecycle cost-effectiveness, resilience, and cybersecurity of installation microgrids.
Read more here.

Improving the Cyber Resilience of DoW Installation Energy Systems
This topic focuses on closing critical cybersecurity gaps in Facility-Related Control Systems (FRCS) that support energy and water infrastructure. ESTCP is seeking demonstrations of novel solutions that improve secure connectivity, threat detection, and cyber defense at machine speed, including alternatives to fiber connectivity, high-fidelity honeypots, and AI-driven defensive cyber agents. The goal is to reduce the risk of cyber-physical disruption to mission-critical installation systems without requiring major infrastructure modifications.
Read more here.

Improving the Energy Resilience of DoW Installations
This topic area solicits technologies that enhance the ability of military installations to continue mission-critical operations during energy disruptions. Solutions may include hardware, software, planning tools, infrastructure hardening, or integrated energy-water-control approaches, but exclude LDES-only solutions, which must submit under the LDES topic. Technologies should reduce dependence on imported energy, address regional challenges (e.g., arctic, remote, or arid locations), and demonstrate scalability across multiple installations.
Read more here.

Solutions to Improve Energy Efficiency and Performance of DoW Buildings
This topic seeks demonstrations of innovative retrofit-ready technologies that reduce energy use intensity, lower maintenance burden, improve occupant health, and decrease lifecycle costs in DoD buildings. Technologies of interest include HVAC, building envelope systems, lighting, water heating, waste heat recovery, and integrated control solutions. ESTCP prioritizes solutions that work with existing infrastructure, deliver measurable energy savings, and have a clear pathway to adoption through ESCOs, ESPCs, or utility programs.
Read more here.

Water Resilience on DoW Installations
This topic area focuses on technologies and methodologies that improve the reliability, security, and efficiency of water systems supporting military missions. Areas of interest include potable water reduction, water storage (minimum 8,000 gallons), desalination improvements, leak detection, corrosion-resistant materials, building-scale water reuse, and advanced water monitoring. Solutions should reduce operational burden, address water-stressed regions, and support long-term resilience of aging installation water infrastructure.
Read more here.

Are there any additional benefits I would receive?

Beyond the direct funding award, ESTCP provides significant strategic advantages:

  • DoD Validation and Credibility: ESTCP selection signals that your technology meets high-priority DoD installation needs and has passed rigorous technical review.

  • Accelerated Adoption Pathways: Demonstrations are explicitly designed to support transition, regulatory acceptance, and scaling across multiple DoD installations.

  • Non-Dilutive Growth: ESTCP funding allows companies to mature and validate technology without giving up equity, strengthening long-term enterprise value.

  • Visibility with Defense Stakeholders: Successful projects are published, presented, and shared across DoD, regulatory, and industry communities—raising profile and credibility.

What is the timeline to apply and when would I receive funding?

  • Pre-Proposals Due: March 26, 2026 (2:00 p.m. ET)

  • Full Proposal Invitations: May 2026

  • Full Proposals Due: July 2026

  • Technical Committee Briefings: August 2026

  • Project Selection: September 2026

  • Anticipated Contract Awards: Q3 FY 2027.

Where does this funding come from?

Funding is provided by the Environmental Security Technology Certification Program (ESTCP) under the Office of the Deputy Assistant Secretary of Defense (Energy Resilience & Optimization) within the U.S. Department of Defense.

Who is eligible to apply?

Eligibility depends on organization type:

  • Private industry and universities: Apply under the FY27 ESTCP Broad Agency Announcement (BAA)

  • DoD organizations: Apply under the FY27 DoD Call for Proposals

  • Other Federal agencies: Apply under the FY27 Federal Call for Proposals

All proposers must submit a pre-proposal and respond to an eligible Topic Area.

What companies and projects are likely to win?

Successful proposals typically:

  • Address a clearly defined, enterprise-wide DoD installation need

  • Demonstrate technologies at TRL or ARL 5–7

  • Provide strong cost, performance, and risk-reduction benefits

  • Include a clear DoD end user and transition pathway

  • Are scalable across multiple installations and Services

Are there any restrictions I should know about?

Projects will not be considered responsive if they:

  • Are already broadly deployed across the DoD enterprise

  • Require access to large volumes of high-quality DoD data

  • Solve a problem unique to a single installation

  • Represent basic research or early-stage exploratory development

How long will it take me to prepare an application?

For first time applicants, pre-proposals will likely take 35 to 50 hours with assistance.

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

  • Triple your likelihood of success through proven strategy and insider-aligned proposal development

  • Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

  • Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth under Federal & State R&D Initiatives.

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, specific topic Josiah Wegner Inactive, specific topic Josiah Wegner

ARPA-H - BIOGAMI: Biomolecular Grammar for Protein Aggregation Modulation and Intervention

Deadline: March 4th, 2026

Funding Award Size: Multi-Million Dollar awards expected

Description: The program’s stated goals include ARPA-H BIOGAMI funds AI-driven platforms, therapeutics, and biomarkers to predict and control protein misfolding before disease onset.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

ARPA-H’s BIOGAMI program is funding teams to predict, detect, and control protein misfolding before disease begins. The program targets intrinsically disordered proteins (IDPs) and regions (IDRs), which are implicated in neurodegeneration, cancer, diabetes, and other chronic diseases and are largely considered “undruggable.”

Solution Summary Due: March 4, 2026 (12:00 PM ET)

Funding & Structure

  1. Awards: Multiple OT awards anticipated

  2. Program Length: Up to 48 months

  3. Phases:

    • Phase 1 (0–24 months): Model IDR behavior and demonstrate early modulation and sensing

    • Phase 2 (25–48 months): Translate to preventative therapeutics and early detection tools

  4. Down-selection occurs after Phase 1 based on quantitative technical metrics.

What ARPA-H Is Trying to Build

BIOGAMI aims to create a generalizable, reusable platform that can:

  • Predict IDR structure, dynamics, aggregation, and interactions from sequence

  • Modulate protein folding to prevent or reverse aggregation

  • Identify early indicators of misfolding—before symptoms appear

  • Enable new therapeutic classes for currently undruggable targets

The program emphasizes root-cause intervention, not symptomatic treatment.

Technical Scope (Both Required)

Technical Area 1 (TA1): Molecular Grammar of IDRs

TA1 teams must establish foundational models that explain how IDR sequences and environments drive protein behavior.

Key requirements include:

  • Integrated AI/ML + experimental approaches

  • High-throughput in vitro, cell-based, and in vivo systems

  • Prediction of structure, aggregation, condensate formation, and interactomes

  • Validation across diverse sequences, conditions, and post-translational modifications

  • Open-source sharing of TA1 models and datasets

By Phase 2, models must predict and validate IDR properties within 60 days of receiving a sequence.

Technical Area 2 (TA2): Modulate IDPs to Detect and Control Folding

TA2 focuses on therapeutic and diagnostic translation.

Teams must:

  • Prevent or reverse aggregation and restore protein function

  • Develop early, clinically translatable indicators of misfolding

  • Target two diseases:

    • One rare disease (<1 in 100,000)

    • One non-rare disease
      (across neurodegenerative and non-neurodegenerative categories)

By Phase 2, teams must:

  • Demonstrate in vivo efficacy

  • Preserve or restore >90% of critical protein function

  • Validate ≥1 novel biomarker and prepare for FDA Biomarker Qualification engagement

Eligible Applicants

  • Startups and large companies

  • Universities and nonprofits

  • Multi-party teams required (not prime/sub)

  • Not eligible:

    • FFRDCs and government entities as performers

    • Entities from covered foreign countries or foreign entities of concern

  • Work is prioritized to be performed in the United States.

Evaluation Criteria (In Order)

Scientific and technical merit

  1. Team capability and experience

  2. Relevance to ARPA-H mission and health impact

  3. Cost realism and value

Commercialization Expectations

  1. 5-year and 10-year commercialization plans required

  2. Translation Advisory Board required

  3. Active or planned commercial partnerships strongly encouraged

  4. TA2 outputs expected to be positioned for pre-clinical development

How can BW&CO help?

BW&CO helps biotech and deep-tech teams quickly determine whether BIOGAMI is the right opportunity and, if so, how to pursue it with a credible, ARPA-H–ready strategy by translating dense solicitation language into clear founder-level guidance, pressure-testing technical and team fit against TA1/TA2 requirements and metrics, shaping a compelling program narrative that aligns AI, biology, and validation, designing compliant multi-party teaming structures, aligning commercialization and open-source expectations, and proactively flagging proposal risks—so teams can move confidently toward a competitive submission or make an informed decision to walk away.

How much would BW&CO Charge?

With a flat rate of $4000, you’d work with our grant writing team to put the solution summary together and submit before the March 4th deadline.

Additional Resources

Review the solicitation here.

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Inactive, specific topic Josiah Wegner Inactive, specific topic Josiah Wegner

MassVentures START (SBIR TARgeted Technologies) Program Round 1 Grants

Deadline: February 26th, 2026

Funding Award Size: Round 1 - $100k with total rounds equaling $800k

Description: The program’s stated goals include commercialization, job growth, manufacturing expansion, and statewide innovation.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

MassVentures’ START program provides non-dilutive grants to help Massachusetts companies that have already won a federal Phase II SBIR or STTR award (or equivalent) move toward commercialization. The program’s stated goals include commercialization, job growth, manufacturing expansion, and statewide innovation.

Who should apply?

  1. You are a Massachusetts company that conducts R&D, manufacturing, and commercialization primarily in MA, and is committed to continuing to do so.

  2. You have received a federal Phase II SBIR or STTR award (or equivalent).

  3. You expect to spend START funds primarily in Massachusetts.

Timing note: There is no strict requirement on when your qualifying Phase II was received. If it was more than five years ago, you’re expected to explain why it’s still commercially relevant today.

Funding snapshot:

16 winners will receive $100k in Round 1 in 2026 (paid in two installments). Round 1 winners will be eligible to compete for 7 Round 2 awards in 2027 for $200k. Round 3 is finally for $500k for 3 awardees.

Key dates:

  • Application deadline: Monday, February 23, 2026 — 11:59 PM ET

  • Top 16 selected - March 23, 2026

  • Winners Notified - April 30th, 2026

  • Winner’s breakfast - May/June

What you must submit:

  1. 2026 Application Cover Sheet (contact information)

  2. 1000-word summary covering: the technology, its commercial potential, and the team

  3. 3-minute video

  4. Cover page of your SBIR Phase II award contract (proof of award)

How applications are evaluated:

This RFP references learning “what makes a successful application” and “what judges look for” during the info session, but it does not list formal scoring criteria in the text provided.
What is explicitly required in the application suggests emphasis on:

  • Clear explanation of the technology

  • Credible commercial potential

  • Strength of the team

Practical guidance for CEOs

  1. Treat the 1000-word summary as your “investment memo”: what it is, why it wins, how it becomes a business.

  2. Use the 3-minute video to make the story memorable and concrete: problem → solution → proof → market → plan.

  3. If your Phase II is older than 5 years, be direct about why it still matters commercially now.

How can BW&CO help?

BW&CO helps founders and CEOs decide quickly whether this opportunity is worth pursuing and how to win it. We translate the START RFP into plain-English strategy, pressure-test fit and competitiveness, shape a clear commercialization narrative for the 1,000-word summary and 3-minute video, and manage the application end-to-end so your team stays focused on building the business. Our goal is to reduce time burden, avoid preventable mistakes, and submit a credible, CEO-ready application aligned with what MassVentures is explicitly asking for.

How much would BW&CO Charge?

With a flat rate of $2500, you’d work with our grant writing team to put the application together and submit before the February 23rd deadline.

Additional Resources

Review the solicitation here.

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Inactive, specific topic Josiah Wegner Inactive, specific topic Josiah Wegner

5G Deployable Systems – Department of Homeland Security (DHS)

Deadline: March 2, 2026

Funding Award Size: Est. Future $500K to $5 million (Currently RFI Only)

Description: Market research request for deployable 5G systems to support DHS operational needs.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The Department of Homeland Security (DHS) Science and Technology Directorate (S&T) is conducting market research to identify deployable 5G systems that can support DHS operational needs. This Request for Information (RFI) is intended to collect technical, operational, and cost-related information from vendors to inform potential future procurement decisions. Responses must be submitted through the Vulcan platform by March 2, 2026 at 12:00 PM Eastern Time.

How much funding would I receive?

Est. $500K to $5 million in the future, however this is currently only a Request for Information (RFI) only.

What could I use the funding for?

DHS is requesting information on deployable 5G system capabilities.

Are there any additional benefits I would receive?

While no funding is initially provided, responding to this RFI will offer strategic benefits, including early visibility into DHS operational requirements, increased exposure to DHS S&T stakeholders, and the opportunity to be considered for future solicitations informed by this market research. DHS also notes that it may conduct one-on-one meetings and system demonstrations with selected respondents as part of its evaluation process.

What is the timeline to apply and when would I receive funding?

Responses must be submitted no later than March 2, 2026 at 12:00 PM Eastern Time via the Vulcan platform. No funding will be awarded under this RFI but funding could be awarded via other methods in Q4 2026 (estimate).

Where does this funding come from?

No funding is associated with this RFI. It is issued solely for information gathering and market research purposes by DHS S&T.

Who is eligible to apply?

Any vendor capable of providing deployable 5G systems that meet DHS operational needs may submit a response. Respondent technologies must be at Technology Readiness Level (TRL) 7 or higher.

What companies and projects are likely to win?

DHS explicitly requests information from systems that:

  • Are deployable and operationally relevant to DHS missions

  • Support 4G LTE, 5G NSA, 5G SA, and/or ORAN technologies

  • Demonstrate TRL 7, 8, or 9 maturity

  • Include detailed performance, security, and cost data

  • Can be demonstrated in a 1-to-2-day operational demonstration

Are there any restrictions I should know about?

Yes. DHS explicitly states that it does not intend to receive proprietary, trade secret, or confidential business information, and all submissions become the property of the U.S. Government. Participation does not transfer any intellectual property rights, and DHS is not obligated to issue a future solicitation.

How long will it take me to prepare an application?

The RFI requires a detailed technical response covering system design, performance, security, deployment, cost models, and supporting documentation. Preparation time will vary, but respondents should expect a non-trivial effort comparable to a technical white paper plus cost and demonstration planning materials.

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

  • Triple your likelihood of success through proven strategy and insider-aligned proposal development

  • Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

  • Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth under Federal & State R&D Initiatives.

How much would BW&CO Charge?

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, specific topic Josiah Wegner Inactive, specific topic Josiah Wegner

Position, Navigation, & Timing at the Tactical Edge – Cyber & Specialist Operations Command (CSOC)

Deadline: April 30, 2026.

Funding Award Size: Est. $500K to $5 million

Description: Market research call seeking Assured and Alternate Position, Navigation, & Timing technologies enabling operations in GNSS-denied or contested environments across dismounted, vehicle, maritime, and uncrewed platforms.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

Cyber & Specialist Operations Command (CSOC) is seeking Assured and Alternate Position, Navigation, & Timing (APNT) technologies that enable military forces to operate effectively in GNSS-denied, contested, or degraded environments. This call supports market research via Vulcan scout card submissions for solutions applicable to dismounted soldiers, vehicles, maritime platforms, and uncrewed systems. Submissions are due by April 30, 2026.

How much funding would I receive?

Est. $500K to $5 million. No funding amount is specified in the source materials. This call is explicitly positioned as market research, not a guaranteed funding award however almost certainly selected technologies will inform future procurement, trials, and funded programs.

What could I use the funding for?

Cyber & Specialist Operations Command is interested in Assured and Alternate Position, Navigation, & Timing (APNT) technologies for use by dismounted soldiers or on vehicle platforms, both static and on-the-move. The proposals should be able to contribute to the ability for Force Elements to continue to operate in a GNSS denied, contested, or degraded environment.

Potential use cases could include:

  • Dismounted Soldier

  • Maritime Mobility (Surface and Sub-Surface)

  • Land Mobility Vehicles

  • Uncrewed Vehicles (in all domains)

Technologies should be compatible with existing systems (i.e. plug and play) and may be hardware based or software based (for example, data fusion engines).

Are there any additional benefits I would receive?

Beyond any future funding opportunity, participation offers meaningful indirect benefits:

Government Validation and Strategic Visibility:
Engaging directly with CSOC provides early validation from the UK Ministry of Defence’s lead command for cyber and specialist operations, signaling relevance to NATO-aligned defence priorities.

Positioning for Follow-On Contracts:
Market research submissions often inform future trials, procurements, and funded defense programs, positioning companies early in the acquisition pipeline.

Access to a High-Value Defence Ecosystem:
CSOC operates across cyber, intelligence, special operations, and electromagnetic domains, creating downstream opportunities for collaboration with allied forces, primes, and specialist units.

What is the timeline to apply and when would I receive funding?

Submission Deadline: April 30, 2026 at 18:59 CDT

No funding or award timeline is specified in the materials.

Where does this funding come from?

This opportunity is issued by the Cyber & Specialist Operations Command (CSOC) of the United Kingdom Ministry of Defence. No specific funding vehicle or appropriation is identified.

Who is eligible to apply?

Everyone - including US Companies.

What companies and projects are likely to win?

Based on the stated interests, strong submissions are likely to demonstrate:

  • Proven or plausible performance in GNSS-denied or contested environments

  • Applicability across multiple platforms or domains

  • Plug-and-play compatibility with existing systems

  • Maturity suitable for military evaluation or experimentation

Are there any restrictions I should know about?

Duplicate scout cards are not permitted and will be removed.

How long will it take me to prepare an application?

Initial participation requires submission of a Scout Card. For a first time applicant this will take 20-40 hours to submit without assistance from BW&CO.

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

  • Triple your likelihood of success through proven strategy and insider-aligned proposal development

  • Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

  • Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth under Federal & State R&D Initiatives.

How much would BW&CO Charge?

Our full service support is available for a flat fee of $4,000 for the Scout Card Submission.

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Project WILLFUL – Next Generation Specialist Vehicles – Cyber & Specialist Operations Command (CSOC)

Deadline: Submit ASAP while funds are available. Closes 1/1/27

Funding Award Size: Est. $500K to $5 million

Description: Funding and collaboration to research, integrate, and demonstrate novel technologies on a high-mobility specialist vehicle platform to inform future UK land manoeuvre capabilities.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

Project WILLFUL is a long-term UK Ministry of Defence R&D and experimentation initiative led by Cyber & Specialist Operations Command (CSOC) to inform a parallel land manoeuvre programme over the next 10–15 years. US Companies are eligible to apply. Through Collaborative Working Innovation Contracts (CWICs, the UK analogue to a CRADA), CSOC will collaborate directly with industry to mature and demonstrate novel technologies on a light, high-mobility 4x4 specialist vehicle platform. Submissions are accepted via Scout Cards until 01 January 2027.

How much funding would I receive?

Est. $500K to $5 million. Funding is expected to be provided through CWICs and related collaborative R&D and capability demonstration activities over the lifetime of the project.

What could I use the funding for?

Funding and collaboration under Project WILLFUL may be used to research, develop, integrate, and demonstrate novel technologies aligned to the following Technology Interest Items:

Alternative Powertrains. Realising the benefits of electric motors at the axels or wheel stations without sacrificing the requirement to run on traditional and dirty fuels. Novel hybrid solutions that are optimised for performance, not emissions. Reduce training, cognitive load on the operator and maintenance. Afford 'silent' approach (reduced audio and thermal signature). Increase exportable power for sub-systems. Future proof for the point where pure EV becomes viable. Improve torque characteristics.

Increasing Payload. Powered Trailers. UGVs. Modified third axles. Novel chassis construction.

C-UAS. Hard and soft kill.

Signature Management. Either through physical profile, such as additive manufacturing solutions or modifiable body kits. Or mounted reductive systems for thermal, audio, IR, EM, RF and counter MLM-enabled object recognition.

Exportable Power. Generation and distribution. Power harvesting.

Protection. Modular ballistic protection. Modular blast protection. Soft kill DAS.

Low profile and light weight Remote Weapons Station. Specifically, options that can be either fitted or removed quickly without specialist tools or can be hidden within vehicle architecture and brought to bear when needed.

Are there any additional benefits I would receive?

Beyond direct R&D collaboration, participation in Project WILLFUL offers significant indirect benefits. Working directly with CSOC and specialist end users provides early insight into future UK land manoeuvre requirements and long-term capability direction. Successful contributors gain credibility through direct Ministry of Defence collaboration, access to spiral acquisition pathways over a 10–15 year horizon, and positioning for follow-on programmes as requirements mature. The use of CWICs enables deeper technical collaboration than traditional procurement mechanisms.

What is the timeline to apply and when would I receive funding?

Vendors are encouraged to submit Scout Cards as early as possible, as engagement, experimentation opportunities, and CWIC pathways may be pursued on a rolling basis as funds and collaboration slots are allocated. Early submissions are more likely to influence ongoing research, experimentation, and requirement-setting activities.

The Scout Card submission window opened on 26 January 2026 at 18:00 CST and formally closes on 01 January 2027 at 17:59 CST. Project WILLFUL is expected to continue throughout the full spiral delivery of the associated land manoeuvre programme over 10–15 years, with capability interest areas and CWICs reviewed periodically.

Where does this funding come from?

Funding and collaboration are provided by the United Kingdom Ministry of Defence, delivered through Cyber & Specialist Operations Command (CSOC) using procurement reform mechanisms and Collaborative Working Innovation Contracts (CWICs).

Who is eligible to apply?

There is no initial threshold requirement for vendors at first consideration. However, to proceed beyond initial review and toward CWIC award, vendors will be required to share information at UK SECRET. Security accreditation may inform down-selection.

As a baseline, vendors should seek to secure:

  • Facility Security Clearance

  • Suitable personnel security clearances (UK SECRET or equivalent)

  • United Kingdom Security Vetting (GOV.UK clearance levels)

What companies and projects are likely to win?

Projects most likely to succeed are those that:

  • Demonstrate novel technologies aligned to the listed Technology Interest Items

  • Can integrate solutions onto a light, high-mobility 4x4 military-spec platform

  • Support rapid experimentation, spiral development, and evolving requirements

Are there any restrictions I should know about?

Subsequent participation beyond initial consideration will require the ability to handle information classified at UK SECRET. Security accreditation and vetting may restrict participation for vendors unable to meet these requirements.

How long will it take me to prepare an application?

Initial participation requires submission of a Scout Card. For a first time applicant this will take 20-40 hours to submit without assistance from BW&CO.

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

  • Triple your likelihood of success through proven strategy and insider-aligned proposal development

  • Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

  • Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth under Federal & State R&D Initiatives.

How much would BW&CO Charge?

Our full service support is available for a flat fee of $4,000 for the Scout Card Submission.

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

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Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Science & Technology Long Range Broad Agency Announcement (LRBAA 24-01) – Department of Homeland Security

Deadline: Submit ASAP while funds are available. Closes 5/31/29

Funding Award Size: Est. $500K to $5 million

Description: Funding for scientific and technical research that enhances homeland security capabilities across DHS operational environments and mission areas.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The Department of Homeland Security (DHS) Science and Technology Directorate (S&T) is funding scientific and technical research projects that significantly improve or increase capabilities across the Homeland Security Enterprise. This Long Range Broad Agency Announcement (LRBAA 24-01) supports near-term operational needs, foundational science, and future/emerging threat research through contracts, grants, cooperative agreements, and Other Transaction Agreements (OTAs). Apply before funds are fully utilized.

How much funding would I receive?

Est. $500K to $5 million. The LRBAA does not specify minimum or maximum award sizes. Funding amounts depend on the technical merit of the proposal, relevance to DHS mission needs, and availability of funds. DHS may fund all, some, or none of the proposals received, and multiple awards are anticipated

What could I use the funding for?

Funding under this LRBAA may be used for research, development, test, and evaluation (RDT&E) activities aligned with DHS Science & Technology Directorate mission needs. DHS is currently seeking projects across the following priority research topic areas. See full topic descriptions here.

Counter Terrorism and Homeland Security Threats (CTHOM)
DHS S&T works to identify individuals or groups that intend to conduct terrorist attacks and/or illicitly move weapons, dangerous goods, and contraband. It also provides assessments of high-consequence attack methods such as CBE threats that terrorists may use to attack the United States.

CTHOM 01: Development of Tools for Test and Evaluation of Machine Learning Algorithms
DHS S&T seeks development of cost-effective methodologies and tools for training and testing of Machine Learning-based (ML-based) algorithms for detecting explosives and contraband in Computed Tomography (CT) and Millimeter Wave (MMW) images. This includes methods to synthesize training and testing data, methods to perturb empirical data in order to explore and explain algorithm performance characteristics, and tools to assess the completeness and diversity of training and test data sets.

CTHOM 03: Novel Approaches and Locations for Explosive Performance Characterization and Testing
Enabling research for the characterization and testing of explosives poses a unique challenge for threat characterization. Innovative tools and methods are needed to provide improvements in evaluating legacy approaches to characterization, adapting state-of-the-art technologies in related disciplines, and integrating emerging innovations.

Secure U.S. Borders and Approaches (BORAP)
DHS secures U.S. borders, territorial waters, ports, terminals, waterways, and air, land, and sea transportation systems. DHS S&T invests in border security research and development for technologies and solutions to prevent illicit movement and the illegal entry or exit of people, weapons, dangerous goods, and contraband.

BORAP 01: Screening at Speed
Screening at Speed seeks to mature transformative technologies that increase aviation security effectiveness from curb-to-gate while dramatically reducing wait times and improving passenger experiences.

BORAP 04: Countering Unmanned Aircraft Systems
The primary objective of this LRBAA is to develop enhanced technologies and methods that allow for the detection, tracking, identification, and mitigation of unmanned aircraft systems under varied terrains and environmental conditions such as dense urban environments, mass gatherings, critical infrastructure, mobile platforms, and remote terrain.

BORAP 07: Detection Canine Technologies
Detection Canine development interests are focused on canine research and development structure and function, development and testing of canine training aids, and independent operational test and evaluation to advance detection canine performance in operational environments.

Secure Cyberspace and Critical Infrastructure (CYBCI)
Protecting individuals and organizations from cyber attacks requires RDT&E, test and evaluation, and the technology transition of advanced cybersecurity and information assurance solutions to secure current and future critical cyber infrastructure.

CYBCI 02: Shared Cyber Resilience
The research and development of improved models of resilience across networked hardware and software systems and organizations, including automated cyber attack mitigation, resilient machine learning approaches, privacy preservation techniques, secure multi-party computing, and human-machine teaming for cybersecurity.

CYBCI 03: Software and Hardware Supply Chain Assurance
The research and development of tools and techniques to ensure the resilience of the data, software, and hardware used to execute homeland security mission functions, including post-quantum cryptography, secure-by-design architectures, microelectronics, IoT, cloud and edge computing, and DevSecOps supply-chain assurance techniques.

CYBCI 04: Trustworthy and Responsible Artificial Intelligence
Research and development to enable DHS to effectively assess AI/ML systems against technical and mission metrics, provide operators an appropriate level of trust and confidence, and inspire trust in the general public toward AI/ML systems deployed by DHS.

CYBCI 05: Advanced and Emerging Data Computation and Analytics
This topic focuses on novel computational and analytic methods and capabilities for large-scale data sets for DHS missions, including real-time analytics, privacy-enhancing technologies, high-performance computing, digital twins, synthetic data, and advanced analytics to improve mission effectiveness and efficiency.

Are there any additional benefits I would receive?

Beyond the direct funding, LRBAA awards provide several indirect advantages:

  • Government Validation and Credibility: Selection signals strong technical merit and alignment with DHS mission priorities.

  • Pathway to Transition and Deployment: Projects are designed to support operational relevance and transition to DHS components.

  • Access to DHS Test and Evaluation Infrastructure: DHS may provide access to government laboratories and operational test facilities where appropriate.

  • Stronger Long-Term Commercial and Contracting Potential: DHS-funded R&D can increase credibility with future government customers and partners.

What is the timeline to apply and when would I receive funding?

This LRBAA is open through May 31, 2029 at 11:59 PM ET. Companies should apply as soon as possible while funds are available. Submissions follow a three-step process:

  1. Industry Engagement Submission (initial research concept)

  2. Virtual Pitch (by invitation only)

  3. Written Proposal (by invitation only)

Typical DHS response timelines (subject to change):

  • Industry Engagement feedback: ~10 business days

  • Virtual Pitch evaluation: ~21 business days

  • Written Proposal evaluation: ~21 business days

Award timing depends on evaluation outcomes and funding availability.

Where does this funding come from?

Funding is provided by the Department of Homeland Security Science and Technology Directorate (DHS S&T) through the Office of Procurement Operations.

Who is eligible to apply?

Eligible applicants include:

  • U.S. small businesses and large businesses

  • Academic institutions

  • Government laboratories and Federally Funded Research and Development Centers (FFRDCs)

  • Nonprofits and research organizations

Foreign or foreign-owned entities may participate but are subject to export control, foreign disclosure, and other federal review requirements. There are no set-asides, but DHS strongly encourages small business participation.

What companies and projects are likely to win?

Proposals are evaluated based on:

  • Alignment with DHS mission needs and topic relevance

  • Scientific and technical merit of the proposed approach

  • Degree of innovation and potential capability improvement

  • Operational relevance and transition potential

  • Reasonableness of cost and feasibility of execution

Are there any restrictions I should know about?

Key restrictions include:

  • Proposal preparation costs are not reimbursable

  • Only unclassified materials may be submitted

  • Mature commercial products and support services are not eligible

  • Participation in later proposal stages is invitation-only

  • Export control, IP, and data rights requirements apply

How long will it take me to prepare an application?

Without BW&CO’s assistance the Industry Engagement submission would typically take 35-50 hours.

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

  • Triple your likelihood of success through proven strategy and insider-aligned proposal development

  • Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

  • Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth under Federal & State R&D Initiatives.

How much would BW&CO Charge?

Our full service support is available for a flat fee of $4,000 for the Industry Engagement Submission.

Fractional support is $300 per hour.

For startups, we offer a discounted rate of $250 per hour to make top-tier grant consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review the solicitation here.

Read More
Inactive, Broad Topic Josiah Wegner Inactive, Broad Topic Josiah Wegner

Naval Air Warfare Center Aircraft Division (NAWCAD) Office-Wide Broad Agency Announcement (BAA)

Deadline: White Papers Due June, 22nd

Funding Award Size: Est. $500K to $5M

Description: This BAA solicits innovative basic research, applied research, advanced technology development, and prototype efforts that advance naval aviation capabilities and directly support Department of the Navy mission needs.

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The Naval Air Warfare Center Aircraft Division (NAWCAD) Office-Wide Broad Agency Announcement (BAA) is open through June 22, 2026 at 5:00 PM ET, with white papers accepted on a rolling basis throughout the open period.

This BAA solicits innovative basic research, applied research, advanced technology development, and prototype efforts that advance naval aviation capabilities and directly support Department of the Navy mission needs.

NAWCAD may make awards using contracts, grants, cooperative agreements, or Other Transaction (OT) agreements depending on the nature of the work and the level of government involvement required.

Funding & Award Structure

Number of Awards: Multiple awards anticipated

  • Estimated: $500K to $5 million. Award Size: Not predetermined; varies based on technical merit, relevance, and available funding

  • Period of Performance: Varies by project

Possible Award Instruments:

  • Procurement contracts

  • Grants

  • Cooperative agreements

  • Other Transaction (OT) agreements for research or prototypes

The Government reserves the right to fund all, some, or none of the submitted proposals and may fund efforts incrementally or with options.

Research Areas

Advanced Manufacturing (Priority). Areas of research include but are not limited to the following: multi-functional aircraft components to enable mission flexibility and platform interoperability, aircraft part digital repository and large-scale complete part printing, and manufacture-on-demand of Naval aviation assets.

Aeromechanics. Areas of research include but are not limited to the following: aerodynamic and flight controls (manned and unmanned), aeromechanics modeling and analysis tools, flight performance, rotorcraft aerodynamics and performance, ship/aircraft aerodynamic interactions, and unmanned aviation and integration including pilot augmentation and automation and UAV autonomous landing flight mechanics.

Artificial Intelligence (AI) / Machine Learning (ML) (Priority). Areas of research include but are not limited to the following: AI/ML-driven signal and analysis type sensing, complex reasoning, multi-agent based operation and decision making, airspace integration including sense and avoid algorithms, deep reinforcement learning, neural networks, and demand forecasting.

Autonomy (Priority). Areas of research include but are not limited to the following: autonomous air-to-air refueling, autonomous system development, testing, evaluation, verification and validation tools, airworthiness and risk quantification/acceptance, collaborative autonomy, and autonomous system precision takeoff and landing.

Avionics, Sensors & Electronic Warfare. Areas of research include but are not limited to the following: multi-modal sensors, passive and active sensor systems (RF, EO/IR, and acoustic), advanced or alternative precision navigation and timing (PNT), advanced computational and open system architectures, advanced signal and image processing, flight information and control systems, and advanced concepts in electronic warfare systems.

Cyber (Priority). Areas of research may include but are not limited to the following: high accuracy threat detection, cyber effects modeling, reverse engineering, behavioral analysis, intrusion, adaptive cybersecurity, simulation and interface research, concolic testing, and systems configuration management.

Data Science & Visualization. Areas of research include but are not limited to the following: predictive modeling algorithms, complex big-data environments, data access, storage and retrieval, data visualization techniques, risk assessment and uncertainty quantification, and statistical analysis.

Digital Engineering (Priority). Areas of research include but are not limited to the following: advancements in the use of Digital Twin technology to support predictive maintenance, automated sustainment environments, diagnostics and prognostics, digital communication of system requirements using model-based systems engineering (MBSE) and Systems Modeling Language (SysML) views, and engineering models and virtual environments to test designs across broader parameters than what live testing permits.

Human Systems. Areas of research include but are not limited to the following: human performance assessment and modeling, cognitive performance and workload, human-machine interface and teaming, protective equipment, controls and displays, ergonomics, anthropomorphic measurement, virtual environments, human factors engineering (social, behavioral, health, and cultural), cognitively enhanced operator-state monitoring, prediction, and recommendation, and human-machine fusion AI-supported operator enhancement.

Hypersonic Systems. Areas of research include but are not limited to the following: external and internal high-speed aerodynamics, multi-physics modeling and simulation, hypersonic system testing and evaluation, high-temperature and high-specific-strength materials, structures and coatings, guidance, navigation and control, and advanced air-breathing propulsion.

Materials and Aircraft Structures. Areas of research include but are not limited to the following: additive manufacturing, corrosion prevention, non-destructive inspection, structural repair and repair processes for metals and ceramics, polymers and composites, analysis and simulation of aircraft structures, structural mechanics, fouling, low observable materials, high-temperature materials, low-temperature icing-resistant materials, and life management of airframes.

Mechanical Systems. Areas of research include but are not limited to the following: fire and ice protection for aviation systems, fuel containment, hydraulic systems, pneumatic systems, and landing gear systems analysis.

Power and Propulsion Systems. Areas of research include but are not limited to the following: reliability engineering, fuel systems, prognostics and diagnostics, energy storage and efficiency, air-breathing engines, fuels and lubricants, electrical power generation, auxiliary power, low observable signature technologies, propulsion life management, mechanical and drive systems, and affordable small- to medium-scale propulsion systems.

Quantum (Priority). Areas of research may include but are not limited to the following: precise self-reliant onboard navigation and threat detection, secure communication and sensing capabilities, nitrogen vacancy diamond sensing, quantum encryption, and quantum computing.

Secure Communications & Networks (Priority). Areas of research include but are not limited to the following: resilient data and communications networks for command and control, architecture, analysis and software development, information assurance including blockchain networks and security, platform and system health monitoring, effective data transfer of communications and video, and end-to-end security integration in software development for autonomous applications operating in dynamic and contested environments.

Support Equipment. Areas of research include but are not limited to the following: launch and recovery equipment, forward-deployed sustainment and resupply, rapid assessment and repair technologies for contested environments, electromagnetics, high-energy generation and control, environmental sensing, prognostics and health monitoring, automatic testing of hardware and software, displays, advanced maintenance technologies, information systems and intelligent agents, and advanced computer and data processing applications.

Test and Evaluation Engineering. Areas of research include but are not limited to the following: telemetry, communications, data links and data acquisition, signature technologies, mission system testing, system-of-systems testing environments, virtual reality (VR), augmented reality (AR), extended reality (XR), target engineering, airborne threat simulation, integrated battlespace simulation (Live Virtual Constructive Environments), hardware-in-the-loop testing, flight instrumentation, ground radar analysis, test article configuration, navigation and identification, manned-unmanned teaming, advanced training systems including instructional techniques and strategies, and game-based training.

Warfare Analysis. Areas of research include but are not limited to the following: operational suitability, signal extraction, clutter reduction, modeling and simulation, maritime effectiveness, vulnerability and capability-based assessment, and conceptual aircraft design.

NAWCAD may also consider submissions outside these areas if the white paper involves the development of novel-based capabilities with potential to enhance naval capabilities.

Who Should Pay Attention

  • Small businesses, startups, and non-traditional contractors (explicitly encouraged)

  • Mid-size and large defense R&D firms

  • Universities and research institutions

  • Teams with novel sensing hardware, algorithms, or system concepts

This is an unrestricted solicitation. Cost sharing is allowed but not required. Foreign entities may not serve as primes.

Deadline

White Paper Deadline: June 22, 2026 at 5:00 PM ET. Only proposers whose white papers are deemed of interest will be invited to submit a full technical and cost proposal.

Evaluation Criteria

Proposals are evaluated using the following criteria, in descending order of importance:

  1. Technical Approach – Innovation, feasibility, completeness, and risk mitigation

  2. Potential Contribution & Naval Relevance – Alignment with NAWCAD and Navy mission needs

  3. Cost – Realism and consistency with the proposed technical approach

Proposals are not evaluated against each other but on their individual merit and relevance.

Bottom Line:

  1. NAWCAD has flexibility to award OTs, which can be more startup-friendly than FAR-based contracts

  2. Successful prototype OTs may be eligible for noncompetitive follow-on production awards

  3. White paper quality is critical; there is no guarantee of a Phase II invitation

How long will it take me to prepare an application?

For a first-time applicant on your own, preparing an White Paper under this BAA will likely take 20–50 hours in total. BW&CO offers services to save you time and increase your likelihood of success.

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

  • Triple your likelihood of success through proven strategy and insider-aligned proposal development

  • Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

  • Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth under Federal & State R&D Initiatives.

How much would BW&CO Charge?

Our full service support is available for a flat fee of $5,000 for the White Paper Submission.

Fractional support is $300 per hour, with most AFRL proposal projects requiring 10-20 hours of expert support from strategy through submission of full proposal.

For startups, we offer a discounted rate of $250 per hour to make top-tier grant consulting more accessible while maintaining the same level of strategic guidance and proposal quality.

Additional Resources

Review solicitation here.

Read More