Status: Open. Proposals are due December 8, 2026, 3:00 PM ET through eCPS. Notice of intent requested by November 6, 2026.
Executive Summary
NIAID estimates up to $16M in FY27 for up to four cost-reimbursement contracts: a needle-free vaccine taken into a clinical trial, therapeutics for listed pathogens, or sequencing-based viral diagnostics. It is not a small business set-aside. Proposals are due December 8, 2026, 3:00 PM ET.
Each research area needs its own proposal through NIH's eCPS portal. NIAID requests a notice of intent by November 6, but will accept it after that date.
Solicitation at a Glance
- Agency: National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Microbiology and Infectious Diseases (DMID)
- Solicitation: 2027 DMID Omnibus Broad Agency Announcement, HHS-NIH-NIAID-BAA2026-1
- Award Vehicle: Cost-reimbursement completion contracts, up to five years
- Funding: Up to $16M in FY27 for up to four contracts (NIAID estimate)
- Set-aside: None; full and open
- Due date: December 8, 2026, 3:00 PM ET via eCPS
Think your company qualifies? Talk with BW&CO before the December 8 deadline.
What Is the DMID Omnibus BAA?
The DMID Omnibus BAA is NIAID's contract solicitation for specific infectious disease product needs. The 2027 edition names three research areas, each competed separately.
What Problem Is NIAID Trying to Solve?
NIAID wants products that move faster toward patients: vaccines that do not need a needle, new therapeutics against priority pathogens, and diagnostics that identify viruses from sequencing data in about two hours.
Research Areas: What NIAID Is Looking For
- Research Area 1: A needle-free vaccine candidate taken into a clinical trial
- Research Area 2: Therapeutics for the listed viral, bacterial and fungal pathogens
- Research Area 3: Sequencing-based viral diagnostics, ideally with results in about two hours
Funding and Award Terms
- Amount: NIAID estimates up to $16M for up to four contracts in FY27
- Type: Cost-reimbursement completion contracts
- Length: Up to five years
- Subcontracting plan: Required from large businesses above $900,000
Eligibility
- Who can apply: Any responsible offeror; the BAA is not set aside for small business
- Size standard: NAICS 541715, 1,000 employees
- Scope rule: A vaccine proposal without a clinical trial is out of scope
How to Apply
- Send a notice of intent: by November 6, 2026 (requested, not mandatory)
- Write one proposal per research area: the 75-page technical limit includes biosketches
- Submit through eCPS: by December 8, 2026, 3:00 PM ET
What Happens After You Submit?
- Evaluation: NIAID evaluates each proposal under the criteria in the BAA
- Award: NIAID estimates up to four contracts in FY27
Is This Opportunity a Good Fit for Your Company?
It fits companies with a needle-free vaccine ready for a clinical trial, anti-infective developers with data in hand, and diagnostics teams working on fast, sequencing-based virus identification.
How BW&CO Can Help
BW&CO has helped deep-tech and dual-use founders secure more than $350M in non-dilutive funding. For federal contract solicitations like the DMID Omnibus BAA, we help you:
- Pick the right research area: match your product to one area, or decide whether to file more than one
- Send the notice of intent: on time for November 6
- Build the technical proposal: within the 75-page limit, biosketches included
- Prepare the cost proposal: for a cost-reimbursement contract
- Submit through eCPS: with time to spare before December 8
Frequently Asked Questions
When are proposals due?
December 8, 2026, 3:00 PM ET, through NIH's eCPS portal.
Is the notice of intent required?
No. NIAID requests it by November 6, 2026, and will accept it after that date.
How much funding is available?
NIAID estimates up to $16M in FY27 for up to four contracts.
Is this a grant?
No. Awards are cost-reimbursement contracts of up to five years.
Is it limited to small businesses?
No. It is not a small business set-aside.
Can one proposal cover two research areas?
No. Each research area needs its own proposal.
Does a vaccine proposal need a clinical trial?
Yes. A vaccine proposal without a clinical trial is out of scope.
Can BW&CO help with a DMID Omnibus BAA proposal?
Yes. BW&CO can run the contract proposal with you, from the notice of intent to the eCPS submission. Book a call with our team.