Project Development and Supply Chain Reimbursement Program (PDSCRP) – Texas Advanced Nuclear Energy Office (TANEO)

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

The Texas Advanced Nuclear Energy Office is awarding up to $70 million to businesses, nonprofits, and government entities for advanced nuclear project development and supply chain activities in Texas. Opportunities available for both Texas and Non-Texas based companies. Individual awards cover up to 50% of costs or $12.5M. Notice of Intent to apply Due April 23, 2026. Full applications are due May 14, 2026.

How much funding would I receive?

Individual awards are capped at the lesser of:

• 50% of qualifying project expenses

• $12.5 million

What could I use the funding for?

Funding supports reimbursement for expenses related to:

• technology development, including university technology development

• feasibility studies

• site planning, including conceptual site-specific engineering studies

• front-end engineering design

• site and environmental characterization

• Nuclear Regulatory Commission (NRC) early site permit work

• preparation of the construction permit or license application to the NRC commission

• developing manufacturing capacity and readiness

• fuel processing, manufacturing, and fabrication activities essential to the fuel cycle supply

• preparation of local, state, and non-NRC federal permits

• NRC licensing fees

Are there any additional benefits I would receive?

Beyond reimbursement funding, recipients benefit from:

• State-Level Validation: Selection by TANEO signals alignment with Texas’ strategic nuclear energy priorities, which strengthens credibility with regulators, utilities, and investors.

• Access to Texas Energy Ecosystem: Projects integrate into a statewide push to expand advanced nuclear infrastructure, enabling partnerships across manufacturing, academia, and energy providers.

• Workforce and Supply Chain Positioning: Awardees gain early positioning in a developing nuclear supply chain ecosystem, which can unlock long-term contracts and industrial partnerships.

• Stronger Financing Position: Demonstrating partial cost coverage and state backing improves capital stack viability and reduces perceived project risk for private investors.

What is the timeline to apply and when would I receive funding?

• Notice of Intent to Apply: April 23, 2026

• Application Deadline: May 14, 2026

• Grant Selections: Week of July 20, 2026

• Period of Performance Begins: Week of September 14, 2026

Where does this funding come from?

Funding comes from the Texas Advanced Nuclear Development Fund (TANDF), administered by the Texas Advanced Nuclear Energy Office.

Who is eligible to apply?

Eligible applicants include:

• Businesses

• Nonprofit organizations

• Governmental entities (including institutions of higher education)

What companies and projects are likely to win?

Applications are evaluated based on:

• Project feasibility, readiness, and regulatory status

• Economic development impact including job creation and supply chain growth

• Strength of financing plan and cost-effectiveness

• Organizational capability and relevant experience

• Project completion viability and long-term impact in Texas

Are there any restrictions I should know about?

• Only expenses incurred after grant execution are eligible for reimbursement

• Expenses funded by other government sources are not eligible as matching funds

• A Notice of Intent to Apply is mandatory

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

1. Triple your likelihood of success through proven strategy and insider-aligned proposal development

2. Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

3. Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.

How much would BW&CO Charge?

We have both fractional engagements ($300 an hour) and full engagements (Initial Fee quoted upon request + 3-5% Success Fee)

Additional Resources

Review the solicitation here.

Product Development Funding Programs – Cancer Prevention and Research Institute of Texas (CPRIT)

Below is a brief summary. Please check the full solicitation before applying (link in resources section).

Executive Summary:

CPRIT provides flexible, non-dilutive funding to support the development and commercialization of innovative cancer technologies. Through four distinct programs—SEED, TDDC, TTC, and TNTC—CPRIT funds companies across the full lifecycle, from early-stage discovery to late-stage clinical development. Preliminary applications are due April 16, 2026, with full applications due July 9, 2026.

How much funding would I receive?

Funding varies by program:

• SEED Awards: Up to ~$3 million (early-stage)

• TDDC, TTC, TNTC: No fixed cap; funding is flexible and negotiated based on project scope

CPRIT allocates approximately $70 million annually for company investments and distributes funding through milestone-based contracts tied to project progress

What could I use the funding for?

Funding supports research and development of technologies for the prevention, detection, diagnosis, monitoring, and treatment of cancer.

Common use cases include:

• Artificial intelligence and bioinformatics

• Therapeutics (drugs, biologics, cell therapies)

• Diagnostics and medical devices

• Manufacturing and biomanufacturing

• Clinical validation and trials

• Sample quality improvement and research tools

Which CPRIT Program is right for me?

CPRIT offers four programs designed for different stages and technology types:

SEED Awards (Earliest Stage)

• Focus: Preclinical and company formation

• Stage: Discovery → proof-of-concept

• Goal: De-risk early science and make the company investable

• Funding: Up to ~$3M

TDDC (Texas Diagnostic & Device Company Awards)

• Focus: Diagnostics and medical devices

• Stage: Late-stage development (near regulatory submission)

• Goal: Advance toward commercialization and market entry

TTC (Texas Therapeutics Company Awards)

• Focus: Therapeutics (drugs, biologics, cell therapies)

• Stage: IND-enabling through clinical development

• Goal: Advance clinical programs and regulatory approval

TNTC (Texas New Technologies Company Awards)

• Focus: Emerging and non-traditional technologies

• Stage: Varies

• Examples: AI, platforms, research tools, enabling technologies

• Goal: Support innovations that do not fit neatly into therapeutics or devices

What is the application process?

All CPRIT programs follow the same two-stage, competitive process:

Stage 1: Preliminary Application (Initial Screening)
Applicants submit:

• Abstract

• Executive summary (≤2 pages)

• Slide deck (≤16 slides)

• Project aims and budget

Applications are reviewed for scientific merit and alignment with CPRIT priorities. Only top applicants are invited to proceed.

Stage 2: Full Application (Deep Diligence)
Invited companies submit:

• Integrated product development plan (technical, clinical, regulatory)

• Full business plan (market, competition, commercialization, financials, IP)

• Timeline and milestones

• Management team and execution plan

Applicants present to an expert panel and undergo due diligence before final selection.

Final Decision Process

• Scientific and product review

• Due diligence

• Program Integration Committee review

• Final approval by CPRIT Oversight Committee

Funding is awarded via milestone-based contracts tied to performance.

What is the timeline to apply and when would I receive funding?

• Preliminary Application Opens: April 7, 2026

• Preliminary Application Deadline: April 16, 2026

• Full Application Invitation: June 2026

• Full Application Deadline: July 9, 2026

• Award Period: September 1, 2026 – August 31, 2027

Funding is deployed over multiple years based on milestone completion.

Where does this funding come from?

Funding is provided by CPRIT through $6 billion in Texas taxpayer-backed general obligation bonds dedicated to cancer research and commercialization.

Who is eligible to apply?

Applicants must be:

• Texas-based, for-profit companies (or willing to relocate)

• Able to meet Texas presence requirements (e.g., HQ, personnel, manufacturing, or clinical activity in Texas)

• Compliant with CPRIT eligibility rules

What companies and projects are likely to win?

• Address a significant unmet medical need

• Demonstrate strong technical validation

• Show a clear path to commercialization

• Have an experienced management team

• Present a credible regulatory and development strategy

Are there any restrictions I should know about?

• Must maintain a business presence in Texas or be willing to relocate to Texas upon selection for award

• Matching funds are required

• Indirect costs capped at ~5%

• Travel expenses are not reimbursable (can count as matching funds)

• Funding is milestone-based with reporting requirements

How can BW&CO help?

Our team specializes in complex federal R&D proposals and can:

1. Triple your likelihood of success through proven strategy and insider-aligned proposal development

2. Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations

3. Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.

How much would BW&CO Charge?

We have both fractional engagements ($250 an hour) and full engagements ($20,000 + 5%) available (Only $5,000 for preliminary application).

Additional Resources

Review the solicitation here.