Innovation Funding Database
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xTech|Phantum Competition (ARM26BX01-NP003)
Deadline: May 6, 2026
Funding Award Size: $300k
Description: U.S. Army xTech Phantum Competition offers small businesses a path to $300K SBIR funding for quantum sensors and photonics. White papers due May 6, 2026.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The U.S. Army is seeking small businesses developing quantum sensors and photonics technologies through the xTech|Phantum Competition. This is a gated pathway to SBIR funding—only competition winners can submit a Phase I proposal. Companies can earn prize money, engage directly with the Department of War, and position themselves for follow-on SBIR funding.
White paper submission deadline: May 6, 2026
How much funding would I receive?
Phase I SBIR:
Up to $300,000
6-month period of performance
Prize money:
Not specified in the solicitation
What could I use the funding for?
Phase I funding is for feasibility and concept development, including:
Demonstrating technical advantage over existing solutions
Developing concept plans aligned with Army modernization priorities
Providing supporting technical literature and performance data
Building a commercialization strategy (defense and commercial markets)
Creating a technology development roadmap
Delivering a concept demonstration at the end of Phase I
Technology focus areas include:
Quantum sensors and quantum clocks for non-GPS PNT
Quantum RF sensors
Quantum electromagnetic sensors
Photonics for communications and edge processing
Are there any additional benefits I would receive?
Direct engagement with the Department of War (DoW)
Feedback from Army stakeholders to accelerate technology development
Entry into the Army’s Science & Technology ecosystem
Eligibility to submit a Phase I SBIR proposal (only if selected as a winner)
What is the timeline to apply and when would I receive funding?
White paper submission deadline: May 6, 2026
xTech|Phantum competition selection timeline: Not specified
Phase I SBIR award timing: Not specified
Phase I performance period: 6 months
Where does this funding come from?
Assistant Secretary of the Army for Acquisition, Logistics and Technology (ASA(ALT))
U.S. Army Directorate for Strategy & Transformation (DAMI-ST)
Delivered via the xTech|Phantum Competition and Army SBIR program
Who is eligible to apply?
Must participate in the xTech|Phantum competition
Only competition winners are eligible to submit a Phase I SBIR proposal
Additional eligibility requirements are not specified in the provided document.
What companies and projects are likely to win?
The Army is prioritizing companies developing:
Quantum technologies enabling non-GPS positioning, navigation, and timing
Quantum RF sensors with improved sensitivity, bandwidth, and SWaP
Electromagnetic sensors detecting low-power or non-RF signals
Photonics systems for secure, high-speed communications and edge computing
Strong applications will:
Demonstrate clear technical feasibility and differentiation
Show dual-use commercial potential
Align directly with Army modernization priorities
Provide credible pathways to prototype and field deployment
Are there any restrictions I should know about?
Only xTech|Phantum competition winners can submit a Phase I SBIR proposal
Proposals from non-participants or non-winners will not be evaluated
CMMC requirement: Level 1
Other restrictions (e.g., cost share, ownership constraints) are not specified.
How long will it take me to prepare an application?
Not specified in the solicitation
Application requires submission of a white paper by May 6, 2026
How can BW&CO help?
BW&CO can support across both stages of this opportunity:
xTech white paper strategy and drafting
Positioning your technology against Army priorities
Translating commercial tech into defense use cases
Preparing a competitive Phase I SBIR proposal (if selected)
Building commercialization and transition plans aligned with Army expectations
Additional Resources
Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Chemical or Radiation/Nuclear (CRN) Threats
Deadline: October 9th, 2026
Funding Award Size: est. $500k - $2m
Description: NIH/NIAID funding for medical countermeasures against chemical and radiation threats. Supports preclinical R&D, diagnostics, and post-exposure treatments. Deadline: October 9, 2026.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
This NIH opportunity (RFA-AI-27-014) supports the development of medical countermeasures (MCMs) and enabling technologies to address chemical and radiation/nuclear (CRN) threats in civilian settings. The program is administered by NIAID through the Radiation and Nuclear Countermeasures Program (RNCP) and Chemical Countermeasures Research Program (CCRP). It is designed to fund early and preclinical work that can diagnose, mitigate, or treat injuries following exposure.
This is a forecasted opportunity with an Estimated Application Due Date: October 9, 2026. Founders working in radiological, nuclear, or chemical threat preparedness should begin positioning now, as this is a complex NIH cooperative agreement with long lead times.
How much funding would I receive?
Funding amounts are not specified in the solicitation, but we anticipate funding to range from $500k - $2m.
What could I use the funding for?
Funding supports research and development of medical countermeasures and enabling technologies addressing CRN threats, including:
Radiation and Nuclear Countermeasures Program (RNCP):
Radiation-focused models
Biomarkers of radiation damage
Devices to assess and predict injury
Products to improve survival and reduce morbidity across organ systems
Chemical Countermeasures Research Program (CCRP):
Preclinical development of products
Technologies to mitigate or treat injury after exposure to Chemicals of Concern
Solutions designed for post-exposure, civilian mass casualty settings
All work must align with developing capabilities to diagnose, mitigate, or treat acute and delayed effects of radiation or chemical exposure during or after public health emergencies.
Are there any additional benefits I would receive?
Not specified in the solicitation.
What is the timeline to apply and when would I receive funding?
Estimated Post Date: July 10, 2026
Estimated Application Due Date: October 9, 2026
Estimated Award Date: July 1, 2027
Estimated Project Start Date: July 1, 2027
Additional timeline details are not specified in the solicitation.
Where does this funding come from?
This funding is provided by the National Institute of Allergy and Infectious Diseases (NIAID) on behalf of the NIH.
It is authorized under:
Sections 301 and 405 of the Public Health Service Act (42 USC 241 and 284)
Federal Regulations: 42 CFR Part 52 and 2 CFR Part 200
The program is supported by a congressional mandate (Public Law 109-149, Dec. 30, 2005) to advance research addressing chemical and radiological threats.
Who is eligible to apply?
For-profit:
Small businesses
For-profit organizations other than small businesses
What companies and projects are likely to win?
Projects that align closely with the stated program goals, including:
Development of medical countermeasures for radiation or chemical exposure
Technologies addressing post-exposure treatment in civilian mass casualty scenarios
Preclinical-stage innovations with clear pathways to mitigating injury or improving survival
Tools for diagnostics, biomarkers, or injury assessment
Further selection criteria are not specified in the solicitation.
Are there any restrictions I should know about?
Funding instrument is a cooperative agreement
No cost sharing or matching requirement
Additional restrictions are not specified in the solicitation.
How long will it take me to prepare an application?
Given this is an NIH cooperative agreement focused on preclinical and translational research, preparation timelines are typically substantial, but exact expectations are not specified in the solicitation.
How can BW&CO help?
BW&CO can support:
Translating your technology into NIH-aligned positioning
Mapping your solution to RNCP or CCRP priorities
Structuring a competitive preclinical development narrative
Managing the full application process ahead of the October 9, 2026 deadline
Additional Resources
AFRL - Multi-Spectrum Defensive Electronic Warfare (MSDEW) Advanced Research Announcement (ARA)
Deadline: Rolling Submission Deadline
Funding Award Size: $20M–$100M
Description: AFRL MSDEW ARA offers $20M–$100M awards for electronic warfare, sensor fusion, and defense systems. Rolling calls open through 13 JULY 2027.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
This is a rolling Air Force Research Laboratory (AFRL) Advanced Research Announcement (ARA) for the Multi-Spectrum Defensive Electronic Warfare (MSDEW) program. It does not accept proposals directly—you must apply through future “calls” released under this ARA.
The ARA remains open for calls until 13 JULY 2027. Each call will define its own requirements, funding, and deadlines. If you are building advanced electronic warfare, sensor fusion, or multi-domain defense technologies, this is a long-running, high-budget entry point into AFRL funding—but you must actively monitor and respond to individual calls as they are released.
How much funding would I receive?
Total program value: $396,600,000.00
Typical award size:
$20,000,000.00 to $100,000,000.00 per award
Number of awards:
Multiple awards expected
No limit per offeror
The Air Force reserves the right to exceed these amounts if in its best interest
What could I use the funding for?
Funding supports R&D and prototyping in multi-spectrum electronic warfare systems, including:
Sensor development across RF and electro-optical domains
Threat warning and countermeasure systems
Integration of multi-sensor systems across air, space, and cyber
Modeling, simulation, and analysis (MS&A)
Testing, experimentation, and demonstration (including flight tests)
Software development (signal processing, algorithms, interfaces)
System architecture (open systems, integration frameworks)
Transitioning technologies to operational systems
Core technical areas include:
Electro-optic & multi-spectrum countermeasures
Directed energy threat warning
Missile warning systems
Cyber-secure and open EW systems
Are there any additional benefits I would receive?
Potential access to large-scale DoD test environments, including flight testing
Opportunity to transition technologies into Air Force operational systems
Flexible award structures:
FAR-based contracts
Other Transactions (OTs)
Ongoing opportunity to compete for multiple awards over several years
What is the timeline to apply and when would I receive funding?
ARA open through: 13 JULY 2027
Proposal deadlines:
To be determined (TBD) on individual calls
Award timing:
TBD per individual call
Notification typically ~30 days after proposal submission
Period of performance:
TBD per individual call
Where does this funding come from?
Air Force Research Laboratory (AFRL), Sensors Directorate (AFRL/RYW)
Funding supports U.S. national defense and electronic warfare capability development
Who is eligible to apply?
Unrestricted solicitation
Eligible applicants:
Businesses of all sizes
Educational institutions
No cost sharing required
Additional notes:
FFRDCs subject to eligibility determinations
Foreign participation:
Not anticipated but may be allowed case-by-case
No limit on number of proposals per offeror
What companies and projects are likely to win?
Proposals are evaluated primarily on:
Technical Merit (highest priority):
Clear understanding of the problem
Strong, feasible technical approach
Relevant experience and qualified team
Ability to advance the state of the art
Potential to transition to operational use
Cost/Price (secondary):
Realistic and justified cost structure
Projects that are most competitive will:
Integrate multiple sensing modalities
Demonstrate real-world applicability (lab + field/flight testing)
Align with Air Force mission needs
Enable transition to future defense systems
Are there any restrictions I should know about?
Many awards will require Top Secret security capabilities
Export control (ITAR/EAR) may apply
Data rights heavily favor the Government (including unlimited rights for government-funded work)
Strict proposal formatting and submission requirements
Accounting system requirements for cost-reimbursement contracts
Compliance with:
OPSEC
Program Protection Plan (PPP)
Safety regulations
Foreign involvement may be restricted per call
How long will it take me to prepare an application?
Not specified in the solicitation
However:
Proposals are submitted in response to individual calls
Each call will define:
Page limits
Technical and cost requirements
Submissions include both technical/management and cost/business volumes
How can BW&CO help?
BW&CO can support you across the full lifecycle of this ARA:
Monitor and identify relevant MSDEW calls
Position your technology against AFRL priorities
Develop compliant technical and cost proposals
Structure OT vs FAR contract strategy
Build transition narratives aligned to Air Force needs
Manage complex submission requirements and timelines
How much would BW&CO Charge?
Our services range from an hourly engagement at $250 an hour to a full service at $15,000 + 5%.
Additional Resources
NAVAL AIR WARFARE CENTER AIRCRAFT DIVISIONAIR SYSTEMS GROUP, PROPULSION & POWER ENGINEERING BAA
Deadline: September 30th
Funding Award Size: Est. $500K to $5M
Description: Apply for FY26 Navy propulsion and power R&D funding through NAWCAD’s open BAA. Submit white papers by 30 September 2026 across energy, propulsion, and aircraft systems.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
This is a Fiscal Year 2026 Broad Agency Announcement (BAA) from the Naval Air Warfare Center Aircraft Division (NAWCAD) focused on propulsion and power technologies for future Naval aircraft. It is a rolling opportunity covering multiple technical areas (BAA 121–125) with a continuous submission window until 30 September 2026.
The Navy is actively seeking white papers and proposals across electrical power systems, fuels and lubricants, operational energy, maintenance/health monitoring, and propulsion systems. Awards are made on a rolling basis, and funding availability is uncertain—so early engagement is critical.
How much funding would I receive?
Number of Awards: Multiple awards anticipated
Estimated: $500K to $5 million. Award Size: Not predetermined; varies based on technical merit, relevance, and available funding
Period of Performance: Varies by project
Possible Award Instruments:
Procurement contracts
Grants
Cooperative agreements
Other Transaction (OT) agreements for research or prototypes
The Government reserves the right to fund all, some, or none of the submitted proposals and may fund efforts incrementally or with options.
What could I use the funding for?
Funding supports R&D programs aligned to five technical areas:
BAA 121: Advanced aircraft electrical power systems
BAA 122: Fuel and lubricant technology
BAA 123: Aircraft operational energy technology
BAA 124: Condition-based maintenance, diagnostics, and health monitoring
BAA 125: Advanced propulsion system technology
Across these areas, funding can be used for:
Concept feasibility studies
Modeling and simulation
Design and engineering
Prototype development
Testing and demonstration
Data analysis and validation
Programs are expected to include structured phases such as design, fabrication, and verification.
Are there any additional benefits I would receive?
Opportunity to transition technology into Navy aircraft systems
Potential for follow-on funding tied to program success
Direct alignment with Naval Air Systems Command priorities
Ability to structure proposals with optional components for incremental funding
Additional benefits are not explicitly specified beyond contract award and potential transition opportunities.
What is the timeline to apply and when would I receive funding?
Submission window: Open continuously until 30 September 2026
Process:
Step 1: Submit White Paper (≤30 pages)
Step 2: If invited, submit full technical and cost proposal
Expected award timing: Fiscal Years 2025–2029
Awards are made on a rolling basis depending on funding availability and program interest.
Where does this funding come from?
Naval Air Warfare Center Aircraft Division (NAWCAD)
Air Systems Group, Propulsion & Power Engineering Department
U.S. Navy / Naval Air Systems Command (NAVAIR)
Who is eligible to apply?
Eligible applicants include:
Private companies and contractors
Educational institutions
Small businesses and disadvantaged businesses
HBCUs and Minority Institutions
Veteran-owned and women-owned small businesses
Requirements:
Must meet Federal Acquisition Regulation (FAR) responsibility standards
Must be registered in SAM prior to award
Must have adequate accounting systems (for cost-reimbursable contracts)
Not eligible:
Foreign governments or foreign entities
What companies and projects are likely to win?
Proposals are evaluated primarily on:
Primary criteria (equal weight):
Scientific and technical merit
Relevance and contribution to Navy propulsion, power, and energy objectives
Secondary criteria:
Team capabilities and past performance
Cost realism and reasonableness
Winning projects will:
Align tightly with one of the defined BAA technical areas
Demonstrate clear military utility and transition potential
Show strong technical feasibility and ROI
Be ready for transition (especially for operational energy topics targeting near-term deployment)
Are there any restrictions I should know about?
Foreign entities are not allowed to apply
Organizational conflicts of interest must be disclosed and mitigated
SETA contractors cannot simultaneously perform R&D without approval
Subcontracting plans required for proposals over $700,000 (with small business participation goals)
Cost-reimbursable contracts require compliant accounting systems
Government is not obligated to provide requested equipment
Failure to disclose conflicts or meet requirements may result in rejection without evaluation.
How long will it take me to prepare an application?
White Papers are expected to be a few pages up to ~15 pages (max 30 pages)
Full proposals (if invited) require detailed technical and cost volumes
Preparation time is not explicitly specified, but the two-step process is designed to reduce upfront effort by screening via White Papers first.
How can BW&CO help?
BW&CO can:
Identify the strongest-fit technical area (BAA 121–125)
Develop a compliant and compelling White Paper
Position your technology for Navy transition and ROI
Build a full technical and cost proposal if invited
Structure optional work packages to maximize award likelihood
How much would BW&CO Charge?
Our full service support is available for a flat fee of $5,000 for the White Paper Submission.
Fractional support is $300 per hour, with most AFRL proposal projects requiring 10-20 hours of expert support from strategy through submission of full proposal.
For startups, we offer a discounted rate of $250 per hour to make top-tier grant consulting more accessible while maintaining the same level of strategic guidance and proposal quality.
Additional Resources
Review solicitation here.
DE-TA1-0003589: Critical Minerals & Materials Accelerator (CMMA)
Deadline: April 30th
Funding Award Size: $2m
Description: Apply for DOE’s $69M Critical Minerals Accelerator (DE-FOA-0003589). Get up to $2M for prototype projects and $8M for pilot-scale technologies in recycling, semiconductors, and lithium extraction. Deadlines start April 21, 2026.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The Critical Minerals and Materials Accelerator Notice of Funding Opportunity (DE-FOA-0003589) offers up to $69,000,000 to fund prototype- and pilot-scale technologies that strengthen U.S. critical mineral supply chains.
This is a time-sensitive, multi-deadline opportunity:
Letter of Intent Due: 04/21/2026 5pm ET
Application due: Topic Area 1: 05/26/2026 5pm ET; Topic Area 2: 06/22/2026 5pm ET; Topic Area 3: 07/20/2026 5pm ET
DOE is targeting companies that can move technologies from bench scale (TRL 3–4) to prototype (TRL 6) and ultimately to commercialization within 3–7 years.
If you are building technologies in critical minerals processing, recycling, semiconductor materials, or lithium extraction, this is a high-priority funding opportunity with follow-on capital pathways (Phase 2).
How much funding would I receive?
Funding varies by topic area and phase:
Total program funding:
$69,000,000 total available funding
Phase 1 (Prototype Scale):
Topic Area 1: Up to $2,000,000 per award (10–14 awards)
Topic Area 2: Up to $2,000,000 per award (1–5 awards)
Topic Area 3A: Up to $2,000,000 per award (4–6 awards)
Topic Area 3B/3C: $1,000,000 – $3,000,000 per award
Phase 2 (Pilot Scale, competitive down-select):
Up to $8,000,000 per project
What could I use the funding for?
Funding supports prototype and pilot-scale development of critical mineral technologies, including:
Prototyping and piloting technologies proven at bench scale
Scaling materials processing and manufacturing technologies
Validation, benchmarking, and testing in industry-relevant environments
Techno-economic analysis (TEA) and life-cycle assessment (LCA)
Collaboration with national labs and testbeds
Development of domestic supply chain capabilities
Topic areas include:
Recovery and production of critical materials (including rare earths)
Semiconductor materials processing (gallium, germanium, silicon carbide)
Lithium extraction, separation, and processing
Are there any additional benefits I would receive?
Yes. Key non-dilutive and strategic benefits include:
Access to DOE national labs and testbeds
Voucher-supported technical assistance (no cost share required for certain lab work)
Participation in the Critical Materials Collaborative (CMC)
Potential pathway to Phase 2 pilot funding (up to $8M)
Opportunity to attract follow-on private capital
Potential equity participation discussions with DOE during negotiations
What is the timeline to apply and when would I receive funding?
Key deadlines:
Letter of Intent Due: 04/21/2026 5pm ET
Application due: Topic Area 1: 05/26/2026 5pm ET; Topic Area 2: 06/22/2026 5pm ET; Topic Area 3: 07/20/2026 5pm ET
Other timeline milestones:
Anticipated selection: July 2026 – August 2026
Anticipated awards: September 2026 – December 2026
Project period: September 2026 – December 2029
Where does this funding come from?
U.S. Department of Energy (DOE)
Offices:
Advanced Materials and Manufacturing Technologies Office (AMMTO)
Office of Geothermal (OG)
Authorized under multiple federal statutes including the Energy Act of 2020 and Energy Policy Act of 2005.
Who is eligible to apply?
Eligible applicants:
Domestic entities, including:
For-profit companies
Nonprofits
Universities
State/local governments
Indian Tribes
Additional eligibility notes:
Foreign entities are generally not eligible (waiver required)
Work must be performed in the U.S. unless a waiver is approved
FFRDC participation is allowed under specific conditions
What companies and projects are likely to win?
DOE is prioritizing projects that:
Advance technologies from TRL 3–4 to TRL 6
Demonstrate a clear path to commercialization within 3–7 years
Address critical supply chain gaps in U.S. mineral production
Include strong industry partnerships
Show scalability, cost competitiveness, and supply chain integration
Incorporate TEA, LCA, and adoption readiness (ARL) considerations
High-priority solutions include:
Recycling and recovery of critical materials
Semiconductor material processing
Lithium extraction technologies
Are there any restrictions I should know about?
Key restrictions include:
Minimum cost share:
Phase 1: 20%
Phase 2: 50%
Cost share must come from non-federal sources
All work must be performed in the United States (unless waived)
Entities of Concern are prohibited from participation
Applications must:
Be submitted to the correct topic area
Include a prior Letter of Intent
Meet strict formatting and submission requirements
How long will it take me to prepare an application?
Not explicitly specified in the solicitation.
However, based on required components, applications include:
Technical Volume
Statement of Project Objectives (SOPO)
Project Management Plan
Budget and cost share documentation
Letters of commitment
Environmental and compliance documentation
Given the complexity, preparation time is not specified in the solicitation, but the scope suggests a substantial effort.
How can BW&CO help?
BW&CO can support you by:
Positioning your technology against DOE evaluation criteria
Building a clear commercialization and scale-up narrative (TRL → market)
Structuring strong industry partnerships and teaming strategy
Developing TEA/LCA-aligned messaging
Preparing compliant and competitive application materials
Managing submission strategy across topic areas
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
DARPA DSO: Mathematics of Boosting Agentic Communication (MATHBAC)
Deadline: April 30th
Funding Award Size: $2m
Description: Apply to DARPA’s MATHBAC program offering up to $2M for foundational research in agentic AI, communication protocols, and scientific discovery. Proposal deadline: June 16, 2026 at 4:00 p.m. ET.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
DARPA is funding foundational research to mathematically formalize how AI agents communicate, collaborate, and accelerate scientific discovery. This is a highly technical, early-stage research program aimed at breakthroughs—not incremental improvements.
Awards will support teams developing new mathematical frameworks, algorithms, and tools for multi-agent AI systems, with a strong emphasis on theory, not product development.
Key deadlines:
Proposal Abstract Due Date: April 30, at 4:00 p.m. (ET)
Proposal Due Date: June 16, 2026, at 4:00 p.m. (ET)
If you are a research-heavy team working on AI, mathematics, systems theory, or scientific discovery platforms, this is a time-sensitive opportunity to engage DARPA at the frontier of agentic AI.
How much funding would I receive?
Phase I awards: Up to $2,000,000 per award
Number of awards: Multiple awards are anticipated
No total program budget or Phase II award size is specified in the solicitation.
What could I use the funding for?
Funding supports foundational research, specifically:
Developing mathematical frameworks for agent communication protocols
Advancing systems theory and information theory for AI collaboration
Creating algorithms and tools for extracting generalizable scientific principles from data
Designing multi-agent communication systems for scientific discovery
Building software tools to simulate and optimize agent interactions
Explicitly not allowed / not the focus:
Incremental improvements to existing approaches
Product development or application-layer systems
This program is focused on basic and applied research, not commercialization.
Are there any additional benefits I would receive?
Opportunity to work directly with DARPA Defense Sciences Office (DSO)
Participation in a 34-month program with potential continuation to Phase II
Access to IV&V evaluation infrastructure and benchmarking
Ability to collaborate in “Evolution Teams” in Phase II
Potential to influence next-generation AI science discovery paradigms
No additional non-monetary benefits are explicitly guaranteed beyond program participation.
What is the timeline to apply and when would I receive funding?
Key Dates (all ET):
Posting Date: April 7, 2026
Proposers Day: April 21, 2026
Proposal Abstract Due Date: April 30, at 4:00 p.m.
Question Deadline: June 4, 2026, at 4:00 p.m.
Proposal Due Date: June 16, 2026, at 4:00 p.m.
Award timeline:
Estimated Period of Performance Start: September 15, 2026
Program structure:
Total duration: 34 months
Phase I: 16 months
Phase II: 18 months (subject to selection and funding availability)
Where does this funding come from?
Agency: Defense Advanced Research Projects Agency (DARPA)
Office: Defense Sciences Office (DSO)
Program: Mathematics of Boosting Agentic Communication (MATHBAC)
Funding is issued via Other Transaction Agreements (OTs) for Research under 10 U.S.C. § 4021.
Who is eligible to apply?
Eligible:
All responsible sources capable of meeting DARPA’s needs
U.S. and non-U.S. organizations (subject to compliance requirements)
Academic institutions, companies, and research organizations
Encouraged (but not set aside):
Small businesses
Minority-serving institutions
Not eligible:
Federally Funded Research and Development Centers (FFRDCs)
University Affiliated Research Centers (UARCs)
Government entities (as performers under this solicitation)
Additional requirements:
Must comply with security, export control, and nondisclosure requirements
Must submit required representations and certifications
What companies and projects are likely to win?
DARPA will prioritize proposals that:
Deliver novel, non-incremental approaches
Provide strong mathematical and theoretical foundations
Demonstrate feasible, well-structured technical plans
Address either:
TA1: Agent communication protocols
TA2: Discovery of generalizable principles from data
Show clear alignment with scientific discovery use cases
Include baseline metrics and evaluation plans
Identify technical risks and mitigation strategies
Demonstrate team expertise in AI, mathematics, and systems/information theory
Projects focused on end-to-end applications without foundational advances are unlikely to be competitive.
Are there any restrictions I should know about?
Research must not focus on incremental improvements
Program is not intended for product or application development
Must use Other Transaction (OT) structure (not grants/contracts)
Organizational Conflict of Interest (OCI) rules apply
Must comply with Fundamental Research Risk-Based Security Review (FRRBS)
Some research may be required to align with fundamental research guidelines or accept restrictions
Proposals must follow strict DARPA submission templates and attachments
Additionally:
Phase I proposals must not exceed $2,000,000
Must address only one Technical Area (TA1 or TA2) in Phase I
Must include a draft Phase II plan or risk being non-conforming
How long will it take me to prepare an application?
The solicitation does not specify preparation time.
However, based on requirements, applicants should expect significant effort due to:
Detailed technical proposal volumes
Required cost workbook and OT agreement markup
Multiple attachments and templates (A–I, X)
Defined milestones, metrics, and evaluation plans
Need for draft Phase II Statement of Work and ROM cost
This is a high-complexity DARPA proposal.
How can BW&CO help?
BW&CO can support:
Translating your technical concept into a DARPA-aligned narrative
Structuring proposals to meet TA1 or TA2 expectations
Developing clear technical rationale and differentiation
Building evaluation metrics and milestone frameworks
Drafting Phase II strategy and Evolution Team positioning
Ensuring compliance with DARPA formatting and submission requirements
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
ARPA-H: Systematic Targeting Of MicroPlastics (STOMP)
Deadline: May 6th
Funding Award Size: $500k - $10m
Description: Apply to ARPA-H’s STOMP program funding microplastics detection, measurement, and removal technologies. Solution Summary due May 6, 2026 at 5:00PM ET.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
ARPA-H’s Systematic Targeting Of MicroPlastics (STOMP) program is a new funding opportunity focused on detecting, understanding, and ultimately removing toxic microplastics from the human body. This is an early-stage, high-impact program targeting a major and unresolved public health challenge.
To apply, you must first submit a required Solution Summary by Monday, May 6, 2026, 5:00PM ET. Only those encouraged will proceed to a full proposal due Monday, June 22, 2026, 5:00PM ET. These deadlines are firm but noted as subject to change—waiting risks missing your window.
STOMP will fund efforts in measurement and biological understanding now, with removal technologies expected in a later phase.
How much funding would I receive?
Funding is expected to range from $500k - $10m.
What could I use the funding for?
Funding supports R&D aligned with two primary technical areas:
Phase 1:
Develop lab-based measurement tools for nano-sized microplastics in biological tissue
Image and characterize microplastics in organs and cells
Study mechanisms of microplastic trafficking and toxicity
Phase 2:
Translate measurement methods into scalable clinical systems
Develop solutions to remove microplastics from the human body
Are there any additional benefits I would receive?
Access to a multidisciplinary ARPA-H program environment
Opportunity to collaborate across technical domains
Participation in a program aimed at major healthcare impact
No additional non-dilutive benefits (e.g., commercialization support, follow-on funding) are specified in the solicitation.
What is the timeline to apply and when would I receive funding?
Key Dates:
Solution Summary Due: Monday, May 6, 2026, 5:00PM ET
Full Proposal Due: Monday, June 22, 2026, 5:00PM ET
Additional notes:
A Solution Summary is required to submit a full proposal
Proposers will be encouraged or discouraged from submitting a full proposal after summary review
Dates are stated as estimates and subject to change
Award timing:
Not specified in the solicitation
Where does this funding come from?
Advanced Research Projects Agency for Health (ARPA-H)
Notice ID: ARPA-H-SOL-26-152
Who is eligible to apply?
Eligibility criteria are not specified in the provided materials
What companies and projects are likely to win?
Based on stated program goals, competitive proposals will likely:
Focus on microplastics measurement technologies or biological mechanism understanding
Address challenges in detecting nano-sized particles in complex biological systems
Provide novel approaches to understanding toxicity and distribution in the body
Demonstrate strong multidisciplinary teaming, as teaming is encouraged
Align with future translation into clinical and scalable systems
Are there any restrictions I should know about?
A Solution Summary is required before submitting a full proposal
Full proposals are recommended only for those encouraged to proceed
Specific restrictions (e.g., cost share, IP terms, or use of funds) are not specified in the provided materials
How long will it take me to prepare an application?
Not specified in the solicitation
However:
The two-step process (Solution Summary → Full Proposal) requires staged preparation
Teaming is encouraged, which may increase coordination time
How can BW&CO help?
BW&CO can support:
Interpreting ARPA-H program fit and positioning
Drafting compelling Solution Summaries aligned to evaluation criteria
Structuring full proposals for technical clarity and competitiveness
Coordinating multi-partner teams and narrative cohesion
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
Golden Dome for America - Department of War CSO
Deadline: Rolling Submissions
Funding Award Size: $500k - $10m
Description: Apply to the Golden Dome for America Commercial Solutions Opening. Rolling submissions through 30 September 2035 for innovative defense technologies, prototypes, and mission-critical capabilities.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The Office of the Secretary of War (Golden Dome for America) is seeking innovative commercial technologies, services, and capabilities to defend the U.S. homeland against advanced threats including ballistic missiles, hypersonics, cruise missiles, and other aerial systems. This is a long-term, continuously open Commercial Solutions Opening (CSO) designed to rapidly fund and deploy breakthrough solutions using flexible contracting.
This opportunity is open from the date of CSO posting through 30 September 2035. There is no single deadline—submissions can be made on a rolling basis, and additional Calls may define specific due dates.
How much funding would I receive?
Funding is expected to range from $500k - $10m.
There is no restriction on the number, type, value, or frequency of awards
Awards may vary widely in scope, duration, and price
The Government may fund all, part, or none of any submission
Awards may be incrementally funded at the Government’s discretion
What could I use the funding for?
Funding can be used to support:
Prototype projects directly relevant to DoD systems, platforms, components, or materials
Development of innovative commercial technologies and services
Solutions that:
Close capability gaps
Accelerate mission effectiveness
Introduce breakthrough technological advancements
The program prioritizes:
Rapid testing and proof-of-concept efforts
Technologies addressing urgent and complex threats
Applications that significantly improve or transform existing capabilities
Are there any additional benefits I would receive?
Yes. This CSO provides:
Access to Other Transaction (OT) agreements and FAR-based contracts
Opportunity for follow-on prototype or production agreements
Flexible acquisition pathways using streamlined procedures
Ability to collaborate at higher security levels when required
Potential for one-step awards directly from white papers
What is the timeline to apply and when would I receive funding?
The CSO is open from the date of CSO posting through 30 September 2035
White papers may be submitted at any time during this period
Specific deadlines will only be provided in individual Calls or RFPs
Submissions close to the end of the CSO period may not be reviewed in time
Timing for funding decisions is not specified, but:
Reviews are intended to be streamlined and expedient
The Government may communicate for clarification during evaluation
Awards may be made directly from white papers or after an RFP process
Where does this funding come from?
Funding comes from:
Office of the Secretary of War (Golden Dome for America)
Authorized under:
DFARS 212.70 – Commercial Solutions Opening
10 USC 4022 (Other Transaction Authority)
10 USC 3458 (Commercial acquisition authority)
Who is eligible to apply?
Eligible applicants include:
All sources capable of addressing the objectives of the CSO
Traditional defense contractors
Nontraditional defense contractors
Non-profit research institutions
Applicants must comply with:
Applicable security requirements
Conflict of interest disclosures
Note: Entities providing SETA or similar support to GDA may not simultaneously act as performers without prior approval.
What companies and projects are likely to win?
The Government prioritizes:
Breakthrough technologies over incremental improvements
Solutions that address urgent and high-priority mission needs
Proposals that enable:
Rapid testing
Proof-of-concept demonstrations
Accelerated deployment
Evaluation is based on:
Technical merit
Price (must be fair and reasonable)
Overall value relative to mission impact and portfolio balance
Are there any restrictions I should know about?
Yes. Key restrictions include:
White papers:
Must not exceed 10 pages
Proposals (if requested):
Technical volume: max 20 pages
Price volume: max 10 pages
Submissions must:
Be in English
Meet security requirements
Properly mark proprietary information
Additional constraints:
The Government may:
Modify scope, price, or terms
Use one-step or two-step evaluation processes
Select partial proposals
How long will it take me to prepare an application?
White papers are designed to be uncomplicated and limited to 10 pages
A one-step award may be possible if sufficient detail is included
Additional effort may be required if invited to submit a full proposal
How can BW&CO help?
BW&CO can support you by:
Identifying where your technology aligns with GDA mission priorities
Developing a compliant, high-impact white paper
Structuring your submission for one-step award consideration
Positioning your solution as a breakthrough capability
Supporting follow-on proposals if an RFP is issued
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
CDMRP: Peer Reviewed Medical Research Program (PRMRP)
Deadline: TBD
Funding Award Size: $385k - $20m
Description: The FY26 DoD PRMRP offers $385K–$20M+ in non-dilutive funding for medical research, clinical trials, and therapeutic development. Pre-announcement—deadlines not yet specified. Prepare now.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The FY26 Peer Reviewed Medical Research Program (PRMRP) is a pre-announcement from the Department of Defense indicating substantial upcoming funding across a wide range of medical research topics relevant to military health. This is an early signal to begin preparing—applications are not yet open, and deadlines are not specified in this pre-announcement. Once released on Grants.gov, these opportunities will move quickly and require pre-applications or letters of intent.
This program supports everything from early-stage discovery through large-scale clinical trials, with awards ranging from $385,000 up to $20M+ depending on mechanism. Founders and research teams should begin aligning projects now to be competitive when announcements drop.
How much funding would I receive?
Funding varies significantly by award mechanism:
Clinical Trial Award
Planning Phase: up to $800,000
Level 1: up to $6M
Level 2: up to $10M
Level 3: up to $20M
Discovery Award
Up to $385,000
Impact Award
Single PI: up to $2.8M
Partnering PI: up to $3.6M
Lifestyle and Applied Health Research Award
Up to $4.2M
Platform Clinical Translation Award
Up to $15M (with only $8M guaranteed from FY26 funds)
Research Advancement Award
Up to $1.4M
Technology/Therapeutic Development Award
Up to $5.6M
All amounts are total costs (direct + indirect).
What could I use the funding for?
Funding supports a broad spectrum of medical research aligned to congressionally mandated topic areas, including (not exhaustive):
PTSD, traumatic brain injury, suicide prevention
Burn pit exposure, respiratory health
Rare diseases (e.g., Rett Syndrome, Fragile X, mitochondrial disease)
Chronic conditions (e.g., diabetes-related areas not explicitly listed, IBD, fibromyalgia-related analogs where applicable)
Women’s health (e.g., endometriosis, maternal mental health)
Neurological and musculoskeletal conditions
Use cases depend on the mechanism:
Discovery Award: High-risk, early-stage concepts (no preliminary data)
Impact Award: Hypothesis-driven work with preliminary data
Clinical Trial Award: Phase 0–3 trials
Technology/Therapeutic Development: Translating preclinical work into products
Platform Clinical Translation: Multi-indication platforms
Lifestyle and Applied Health: Quality of life, behavioral, and applied interventions
Projects must align to at least one specified topic area.
Are there any additional benefits I would receive?
Validation from the Department of Defense and CDMRP
Access to non-dilutive capital at scale (up to $20M)
Opportunity to support military-relevant health outcomes
Structured pathways for clinical translation and regulatory readiness (e.g., IND/IDE planning support under Clinical Trial Award)
Additional benefits are not further specified in the pre-announcement.
What is the timeline to apply and when would I receive funding?
This is a pre-announcement only
Funding opportunity announcements will be released on Grants.gov
Pre-application and full application deadlines are not specified in this pre-announcement
Submission will require:
Pre-application (e.g., preproposal or letter of intent depending on mechanism)
Full application (often by invitation only)
Periods of performance:
Range from 2 years to 4 years depending on mechanism
Planning phases up to 18 months
Exact award start timelines are not specified.
Where does this funding come from?
FY26 Defense Appropriations Act
Administered by:
Defense Health Agency (DHA) Research and Development
Medical Research and Development Command (MRDC)
Managed through the Congressionally Directed Medical Research Programs (CDMRP)
Who is eligible to apply?
Independent investigators at all career levels
Applies across all award mechanisms
No additional institutional, geographic, or organizational eligibility restrictions are specified in this pre-announcement.
What companies and projects are likely to win?
Based strictly on the solicitation:
Projects that:
Align directly with congressionally mandated topic areas
Demonstrate clear relevance to military health
Show high impact and scientific merit
Competitive profiles by mechanism:
Discovery: Bold, untested ideas without preliminary data
Impact: Strong preliminary data + near-term impact potential
Clinical Trial: Well-developed interventions ready for human testing
Technology/Therapeutic Development: Clear product-oriented outcomes
Platform Clinical Translation: Solutions addressing multiple topic areas
Teams:
May include clinician researchers or industry partners (required in some partnering options)
Further selection criteria are not specified in this pre-announcement.
Are there any restrictions I should know about?
Key restrictions vary by mechanism:
Clinical Trial Award
Cannot support preclinical research
Requires regulatory approvals (e.g., IND/IDE) where applicable
Discovery Award
Cannot include preliminary data
Cannot support clinical trials
Impact Award
Cannot support clinical trials
Lifestyle and Applied Health Research Award
Cannot support animal studies
Technology/Therapeutic Development Award
Cannot support clinical trials
Research Advancement Award
Cannot support clinical trials
All applications:
Must align to specified topic areas
Require pre-application submission (preproposal or LOI depending on mechanism)
How long will it take me to prepare an application?
Not explicitly specified, but based on required steps:
Pre-application required (LOI or preproposal)
Full applications often by invitation only
Clinical trial applications may require:
Regulatory documentation (e.g., IND/IDE)
Exact preparation timelines are not specified in the pre-announcement.
How can BW&CO help?
BW&CO can support:
Opportunity qualification against PRMRP mechanisms
Topic area alignment and positioning
Preproposal / LOI development
Full application strategy and narrative development
Clinical and product translation positioning
Partnering strategy (e.g., clinician or industry PI alignment)
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($13,000 + 5%) available.
Additional Resources
CDMRP: Combat Readiness–Medical Research Program (CRRP)
Deadline: TBD
Funding Award Size: $2.4m
Description: Apply for the FY26 Combat Readiness–Medical Research Program (CRRP) offering up to $2.45M for trauma care, battlefield diagnostics, and readiness solutions. Pre-application required.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The FY26 Combat Readiness–Medical Research Program (CRRP) will fund innovative, high-impact research to improve Warfighter survivability and readiness, with a focus on trauma care and operational medical capabilities. This is a pre-announcement, giving advance notice so teams can prepare—the full funding opportunity with required deadlines has not yet been released.
Critically, application deadlines are not specified in this pre-announcement. Once released, the solicitation will include required pre-application and full application deadlines. Teams should begin preparing now, as this program uses a pre-application screening process with invitation-only full submissions.
How much funding would I receive?
Maximum total funding: $2.45 million (total costs)
Guaranteed funding from FY26: $1.45 million
Remaining funding supports optional research efforts
Period of performance:
Maximum total: 3 years
Base period: 2 years
Optional period: 1 year
What could I use the funding for?
Funding supports translational research in combat casualty care, including:
Battlefield diagnostics, triage, and decision support tools
Treatments to improve care delivery in:
Point of injury
Austere surgical/resuscitative environments
Prolonged casualty care
En route care
Battlefield readiness solutions focused on pre-hospital and operational environments
Projects must be hypothesis-driven and supported by preliminary data and aim to move promising technologies toward real-world trauma care solutions.
Are there any additional benefits I would receive?
Not specified in the pre-announcement.
What is the timeline to apply and when would I receive funding?
This is a pre-announcement only
The full funding opportunity will be posted on Grants.gov
Pre-application submission is required via eBRAP
Full applications are by invitation only
Application deadlines are not specified in this pre-announcement and will be provided when the official solicitation is released.
Where does this funding come from?
FY26 Defense Appropriations Act
Managed by:
Congressionally Directed Medical Research Programs (CDMRP)
Under the Defense Health Agency (DHA) Research and Development – Medical Research and Development Command (MRDC)
Who is eligible to apply?
Independent Investigators at all academic levels, or equivalent
No additional eligibility restrictions are specified.
What companies and projects are likely to win?
Projects most aligned with the program’s intent will:
Address combat casualty care and operational medical challenges
Demonstrate strong preliminary data
Be translational—moving technologies toward real-world use
Show potential to:
Improve survivability
Enable care closer to the point of injury
Inform trauma care guidelines
Are there any restrictions I should know about?
Pre-application is required; full submission is invitation-only
Applications must include preliminary data
Research may include:
Animal models (allowed, not required)
Clinical research (allowed, not required)
Small-scale pilot clinical trials (optional, within performance period)
Applications must conform to the final FOA once released
How long will it take me to prepare an application?
Not specified in the pre-announcement.
However, given the pre-application + invitation-only structure and requirement for preliminary data, teams should expect a multi-phase process and begin preparation early.
How can BW&CO help?
BW&CO can support across the full lifecycle:
Positioning your technology against CRRP focus areas
Developing a competitive pre-application strategy
Translating technical work into clear, reviewer-aligned narratives
Building a data-driven commercialization and impact story
Managing submission through eBRAP and Grants.gov workflows
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($13,000 + 5%) available.
Additional Resources
Project Development and Supply Chain Reimbursement Program (PDSCRP) – Texas Advanced Nuclear Energy Office (TANEO)
Deadline: Notice to Apply April 26, 2026; Full Application May 14, 2026
Funding Award Size: Up to $12.5 Million
Description: Reimbursement funding for advanced nuclear project development, including engineering, permitting, site work, and supply chain manufacturing readiness in Texas.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The Texas Advanced Nuclear Energy Office is awarding up to $70 million to businesses, nonprofits, and government entities for advanced nuclear project development and supply chain activities in Texas. Opportunities available for both Texas and Non-Texas based companies. Individual awards cover up to 50% of costs or $12.5M. Notice of Intent to apply Due April 23, 2026. Full applications are due May 14, 2026.
How much funding would I receive?
Individual awards are capped at the lesser of:
50% of qualifying project expenses
$12.5 million
What could I use the funding for?
Funding supports reimbursement for expenses related to:
technology development, including university technology development
feasibility studies
site planning, including conceptual site-specific engineering studies
front-end engineering design
site and environmental characterization
Nuclear Regulatory Commission (NRC) early site permit work
preparation of the construction permit or license application to the NRC commission
developing manufacturing capacity and readiness
fuel processing, manufacturing, and fabrication activities essential to the fuel cycle supply
preparation of local, state, and non-NRC federal permits
NRC licensing fees
Are there any additional benefits I would receive?
Beyond reimbursement funding, recipients benefit from:
State-Level Validation: Selection by TANEO signals alignment with Texas’ strategic nuclear energy priorities, which strengthens credibility with regulators, utilities, and investors.
Access to Texas Energy Ecosystem: Projects integrate into a statewide push to expand advanced nuclear infrastructure, enabling partnerships across manufacturing, academia, and energy providers.
Workforce and Supply Chain Positioning: Awardees gain early positioning in a developing nuclear supply chain ecosystem, which can unlock long-term contracts and industrial partnerships.
Stronger Financing Position: Demonstrating partial cost coverage and state backing improves capital stack viability and reduces perceived project risk for private investors.
What is the timeline to apply and when would I receive funding?
Notice of Intent to Apply: April 23, 2026
Application Deadline: May 14, 2026
Grant Selections: Week of July 20, 2026
Period of Performance Begins: Week of September 14, 2026
Where does this funding come from?
Funding comes from the Texas Advanced Nuclear Development Fund (TANDF), administered by the Texas Advanced Nuclear Energy Office.
Who is eligible to apply?
Eligible applicants include:
Businesses
Nonprofit organizations
Governmental entities (including institutions of higher education)
What companies and projects are likely to win?
Applications are evaluated based on:
Project feasibility, readiness, and regulatory status
Economic development impact including job creation and supply chain growth
Strength of financing plan and cost-effectiveness
Organizational capability and relevant experience
Project completion viability and long-term impact in Texas
Are there any restrictions I should know about?
Only expenses incurred after grant execution are eligible for reimbursement
Expenses funded by other government sources are not eligible as matching funds
A Notice of Intent to Apply is mandatory
How can BW&CO help?
Our team specializes in complex federal R&D proposals and can:
Triple your likelihood of success through proven strategy and insider-aligned proposal development
Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations
Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.
How much would BW&CO Charge?
We have both fractional engagements ($300 an hour) and full engagements (Initial Fee quoted upon request + 3-5% Success Fee)
Additional Resources
Review the solicitation here.
Engage SOF (eSOF) Capabilities of Interest – U.S. Special Operations Command (USSOCOM)
Deadline: Rolling deadline until December 31, 2026
Funding Award Size: Est. $500K to $5M
Description: Rolling submission program connecting commercial technologies to USSOCOM needs across AI, ISR, cyber, mobility, medical, and more, with multiple non-dilutive funding pathways.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
USSOCOM’s Engage SOF (eSOF) program provides a rolling pathway for companies to submit technologies aligned with Special Operations Forces (SOF) capability needs. Selected solutions may receive funding through contracts, OTAs, SBIR/STTR, or other mechanisms. Submissions are open through December 31, 2026.
How much funding would I receive?
Estimated $500K to $5 Million - Funding is not fixed. Awards vary depending on the pathway and may include contracts, OTAs, SBIR/STTR, CRADAs, or prize competitions.
What could I use the funding for?
Projects must align with USSOCOM Capabilities of Interest (CoIs), including (full list here):
Aviation Systems
Biometrics and Forensics
Command, Control, Communications, and Computers (C4)
Cyberspace Operations
Human Performance/Human Machine Interface
Information Operations
Intelligence, Surveillance, and Reconnaissance (ISR)
Irregular Warfare
Medical Technology
Canine Medicine
Mobility
Power and Energy
Soldier Systems
Weapons and Electronic Attack
Are there any additional benefits I would receive?
Beyond direct funding, there are significant indirect benefits:
Government Validation and Credibility: Selection by USSOCOM signals strong alignment with real-world defense needs and increases trust with DoD stakeholders, primes, and investors.
Direct Access to End Users: eSOF connects companies directly with Program Executive Offices, Directorates, and operators for real-world feedback and validation.
Multiple Contracting Pathways: Companies can transition into OTAs, FAR contracts, CRADAs, or prototype programs without starting from scratch.
Follow-on Opportunities: Successful technologies may progress into experimentation, prototyping, and eventual procurement pathways.
Stronger Exit Potential: Government-backed validation and nondilutive funding can significantly increase company valuation and acquisition interest.
What is the timeline to apply and when would I receive funding?
Submissions are accepted on a rolling basis from March 26, 2026 through December 31, 2026.
Funding timing varies depending on the pathway and evaluation process after submission.
Where does this funding come from?
Funding comes from U.S. Special Operations Command (USSOCOM) and is executed through various federal acquisition and research mechanisms including OTAs, FAR contracts, SBIR/STTR, and others.
Who is eligible to apply?
Any organization capable of providing relevant commercial technologies may apply. Submissions must present unclassified information and align with published Capabilities of Interest.
What companies and projects are likely to win?
Clearly match one or more published Capabilities of Interest
Demonstrate strong technical maturity and real-world applicability
Show measurable impact on SOF mission effectiveness
Meet security and compliance requirements
Provide evidence supporting performance and readiness
Are there any restrictions I should know about?
Submissions must be UNCLASSIFIED
Solutions must align with current Capabilities of Interest to be prioritized
May require CMMC compliance and security vetting
Some pathways may involve classified applications and facility clearance requirements
How can BW&CO help?
Our team specializes in complex federal R&D proposals and can:
Triple your likelihood of success through proven strategy and insider-aligned proposal development
Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations
Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available (Only $4,000 for preliminary application).
Additional Resources
Product Development Funding Programs – Cancer Prevention and Research Institute of Texas (CPRIT)
Deadline: April 16, 2026 (Preliminary), July 9, 2026 (Full)
Funding Award Size: Est. $500K to $10M
Description: Flexible, non-dilutive funding for Texas-based companies or those willing to relocate to Texas developing innovative cancer technologies, including AI, bioinformatics, and emerging platform approaches.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
CPRIT provides flexible, non-dilutive funding to support the development and commercialization of innovative cancer technologies. Through four distinct programs—SEED, TDDC, TTC, and TNTC—CPRIT funds companies across the full lifecycle, from early-stage discovery to late-stage clinical development. Preliminary applications are due April 16, 2026, with full applications due July 9, 2026.
How much funding would I receive?
Funding varies by program:
SEED Awards: Up to ~$3 million (early-stage)
TDDC, TTC, TNTC: No fixed cap; funding is flexible and negotiated based on project scope
CPRIT allocates approximately $70 million annually for company investments and distributes funding through milestone-based contracts tied to project progress
What could I use the funding for?
Funding supports research and development of technologies for the prevention, detection, diagnosis, monitoring, and treatment of cancer.
Common use cases include:
Artificial intelligence and bioinformatics
Therapeutics (drugs, biologics, cell therapies)
Diagnostics and medical devices
Manufacturing and biomanufacturing
Clinical validation and trials
Sample quality improvement and research tools
Which CPRIT Program is right for me?
CPRIT offers four programs designed for different stages and technology types:
SEED Awards (Earliest Stage)
Focus: Preclinical and company formation
Stage: Discovery → proof-of-concept
Goal: De-risk early science and make the company investable
Funding: Up to ~$3M
TDDC (Texas Diagnostic & Device Company Awards)
Focus: Diagnostics and medical devices
Stage: Late-stage development (near regulatory submission)
Goal: Advance toward commercialization and market entry
TTC (Texas Therapeutics Company Awards)
Focus: Therapeutics (drugs, biologics, cell therapies)
Stage: IND-enabling through clinical development
Goal: Advance clinical programs and regulatory approval
TNTC (Texas New Technologies Company Awards)
Focus: Emerging and non-traditional technologies
Stage: Varies
Examples: AI, platforms, research tools, enabling technologies
Goal: Support innovations that do not fit neatly into therapeutics or devices
What is the application process?
All CPRIT programs follow the same two-stage, competitive process:
Stage 1: Preliminary Application (Initial Screening)
Applicants submit:
Abstract
Executive summary (≤2 pages)
Slide deck (≤16 slides)
Project aims and budget
Applications are reviewed for scientific merit and alignment with CPRIT priorities. Only top applicants are invited to proceed.
Stage 2: Full Application (Deep Diligence)
Invited companies submit:
Integrated product development plan (technical, clinical, regulatory)
Full business plan (market, competition, commercialization, financials, IP)
Timeline and milestones
Management team and execution plan
Applicants present to an expert panel and undergo due diligence before final selection.
Final Decision Process
Scientific and product review
Due diligence
Program Integration Committee review
Final approval by CPRIT Oversight Committee
Funding is awarded via milestone-based contracts tied to performance.
What is the timeline to apply and when would I receive funding?
Preliminary Application Opens: April 7, 2026
Preliminary Application Deadline: April 16, 2026
Full Application Invitation: June 2026
Full Application Deadline: July 9, 2026
Award Period: September 1, 2026 – August 31, 2027
Funding is deployed over multiple years based on milestone completion.
Where does this funding come from?
Funding is provided by CPRIT through $6 billion in Texas taxpayer-backed general obligation bonds dedicated to cancer research and commercialization.
Who is eligible to apply?
Applicants must be:
Texas-based, for-profit companies (or willing to relocate)
Able to meet Texas presence requirements (e.g., HQ, personnel, manufacturing, or clinical activity in Texas)
Compliant with CPRIT eligibility rules
What companies and projects are likely to win?
Address a significant unmet medical need
Demonstrate strong technical validation
Show a clear path to commercialization
Have an experienced management team
Present a credible regulatory and development strategy
Are there any restrictions I should know about?
Must maintain a business presence in Texas or be willing to relocate to Texas upon selection for award
Matching funds are required
Indirect costs capped at ~5%
Travel expenses are not reimbursable (can count as matching funds)
Funding is milestone-based with reporting requirements
How can BW&CO help?
Our team specializes in complex federal R&D proposals and can:
Triple your likelihood of success through proven strategy and insider-aligned proposal development
Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations
Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($20,000 + 5%) available (Only $5,000 for preliminary application).
Additional Resources
NRL Long Range Broad Agency Announcement (BAA) for Basic and Applied Research - Naval Research Laboratory (NRL)
Deadline: Rolling Deadline Until September 30, 2026
Funding Award Size: Est. $500K to $5M
Description: Funding for basic and applied research across defense-critical areas including AI, materials, energy, cybersecurity, sensing, and space systems to advance U.S. Navy capabilities.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The Naval Research Laboratory (NRL) is seeking innovative basic and applied research proposals across a wide range of scientific and engineering disciplines. Organizations can submit White Papers through September 30, 2026, with potential follow-on contracts, grants, or other agreements awarded based on technical merit.
How much funding would I receive?
Est. $500k to $5 million.
What could I use the funding for?
Funding supports basic and applied research aligned with Navy priorities, including (verbatim/high-level categories from the BAA):
Systems Directorate (e.g., radar, antennas, computational electromagnetics, information systems, AI/ML, human systems integration)
Materials Science and Component Technology (e.g., energy storage, corrosion, materials processing, bio/chemical detection)
Ocean and Atmospheric Science (e.g., ocean acoustics, remote sensing, environmental modeling)
Space Technology (e.g., spacecraft systems, sensors, propulsion, hypersonics)
Specific topic areas include (selected verbatim examples):
“Virtual simulations and mixed reality systems… situational awareness, and training”
“Data management and exploitation technologies that apply emerging mathematics and machine learning techniques”
“Multi-agent and multi-robot systems, reinforcement learning, game theory”
“Electrochemical energy storage and conversion systems such as batteries and fuel cells”
“Optical sciences… lasers, sensors, and photonic technologies”
“Cyber security, cryptographic technologies, and high assurance computing”
“Spacecraft payloads; spacecraft propulsion systems; advanced materials for spaceflight use”
Many More Topics are listed in the Solicitation (See below).
Are there any additional benefits I would receive?
Beyond the formal funding award, there are significant indirect benefits:
Government Validation and Credibility:
Being selected by the Naval Research Laboratory signals strong technical credibility and alignment with U.S. Navy and DoD priorities.
Access to Defense Ecosystem:
Awardees gain exposure to Navy researchers, program managers, and potential transition partners across defense and aerospace.
Flexible Contracting Pathways:
The BAA allows for multiple award mechanisms (contracts, grants, OTAs), enabling faster and more flexible engagement than traditional procurement.
Follow-On Funding Opportunities:
Successful projects may lead to additional funding phases or expanded research programs based on performance.
Increased Strategic Positioning:
Participation positions companies for future DoD funding, partnerships, and potential acquisition interest.
What is the timeline to apply and when would I receive funding?
White Papers Due: September 30, 2026 (4:00 PM EDT)
Rolling evaluation and invitation for full proposals after White Paper review
Funding timing varies based on evaluation and award negotiations
Where does this funding come from?
Department of Defense (DoD) → Department of the Navy → Office of Naval Research (ONR) → Naval Research Laboratory (NRL)
Who is eligible to apply?
Educational institutions
Small businesses
Small disadvantaged businesses
Historically Black Colleges and Universities (HBCUs)
Minority institutions
Other qualified organizations
What companies and projects are likely to win?
Selections are based on:
Technical merit and scientific quality of the proposed approach
Relevance to NRL research priorities
Potential benefit to the Government relative to cost
Feasibility and innovation of the solution
Cost realism and overall value
Are there any restrictions I should know about?
Must submit a White Paper first before a full proposal
Some topics may require security clearances or classified work
Awards depend on availability of funding
Government may select all, some, or none of proposals
How can BW&CO help?
Our team specializes in complex federal R&D proposals and can:
Triple your likelihood of success through proven strategy and insider-aligned proposal development
Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations
Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
Small UAS & Asymmetric Capabilities CSO Call 001 - Department of the Air Force
Deadline: April 20, 2026
Funding Award Size: Est. $500K to $5M
Description: Funding for development of small, low-cost unmanned aircraft systems capable of autonomous, high-speed, long-range operations in contested environments for asymmetric warfare missions.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The U.S. Air Force is soliciting innovative commercial solutions for small unmanned aircraft systems (sUAS) to support asymmetric warfare missions. Awards may be issued as FAR-based contracts or Other Transaction (OT) prototype agreements, with potential follow-on production. Phase 1 submissions are due April 20, 2026.
How much funding would I receive?
Est. $500k to $5 million.
What could I use the funding for?
Funding is intended to develop short-range, one-way attack UAS platforms with the following characteristics:
Operate at ranges 50+ nautical miles
Speeds exceeding 200 mph
Ground-launched, containerized for mass deployment
Fire-and-forget autonomy with in-flight targeting
Coordination with other platforms
Operation in denied, degraded, intermittent, or low-bandwidth (DDIL) environments
Beyond line-of-sight (BLOS) capability
Low observability
Additional required areas:
Mission planning software integration
Modular hardware/software with open interfaces
Passive sensing capabilities (RF, EO/IR, acoustic, etc.)
Scalable manufacturing and production plans
Training and operational deployment concepts
Are there any additional benefits I would receive?
Beyond the formal funding award, there are significant indirect benefits:
Government Validation and Credibility: Selection by the U.S. Air Force signals strong technical credibility and alignment with national defense priorities, increasing trust with primes, investors, and partners.
Follow-on Production Opportunities: Successful prototype projects under OT authority may lead directly to production contracts without further competition.
Enhanced Market Visibility: Participation positions your company within the defense innovation ecosystem and may lead to additional DoD opportunities.
Ecosystem Access: Engagement with Air Force stakeholders and integration into operational environments can unlock future contracts and partnerships.
Stronger Exit Potential: Demonstrating operational capability under government funding can significantly increase valuation and acquisition interest.
What is the timeline to apply and when would I receive funding?
Phase 1 Solution Brief Deadline: April 20, 2026
Phase 2 Pitch Sessions: April 21 – April 28, 2026
Phase 3 Proposals: By invitation only (date provided after Phase 2)
Funding Timing: Not explicitly stated; occurs after Phase 3 award decisions
Where does this funding come from?
Department of Defense (DoD), specifically:
Department of the Air Force
Air Force Life Cycle Management Center (AFLCMC)
Who is eligible to apply?
Open to U.S. and international vendors
Companies must register in SAM.gov if selected
Must be able to meet potential security clearance requirements (up to SECRET for later phases)
What companies and projects are likely to win?
Demonstrate technically credible, scalable UAS solutions
Show ability to operate in DDIL and GNSS-denied environments
Provide modular, open-architecture systems (no proprietary lock-in)
Prove performance via testing data and reliability metrics
Present clear production scalability and cost efficiency
Are there any restrictions I should know about?
Must comply with:
FY2020 NDAA Section 848
FY2023 NDAA Section 817
2024 American Security Drone Act
Must pass DoD cybersecurity requirements (RMF)
Proprietary interfaces requiring vendor lock-in are not permitted
Potential requirement for facility and personnel security clearances (Phase 3+)
How can BW&CO help?
Our team specializes in complex federal R&D proposals and can:
Triple your likelihood of success through proven strategy and insider-aligned proposal development
Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations
Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
SAF/CDM Commercial Solutions Opening (CSO) – U.S. Department of the Air Force
Deadline: Rolling Submissions until 9/30/26
Funding Award Size: Est. $500K to $5M
Description: Flexible Air Force funding for innovative commercial technologies in AI/ML, cyber, and defense applications through a rolling CSO process with white paper submissions and invited proposals.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The U.S. Air Force is offering funding through a Commercial Solutions Opening (CSO) to support innovative commercial technologies and services that address defense-related capability gaps. Awards are made on a rolling basis through September 30, 2026, and require an initial white paper submission followed by an invited full proposal.
How much funding would I receive?
Funding varies significantly by project. There is:
No fixed award size per project
An estimated total program budget of ~$100M across all awards
Awards may be incrementally funded and vary widely in scope, duration, and value
What could I use the funding for?
Funding supports innovative commercial items, technologies, and services aligned with Air Force mission needs, including:
Big Data, Artificial Intelligence and Machine Learning (AI/ML), technologies and processes
Emerging cyber technologies and methodologies
Countering strategic competitors’ malign influence
Are there any additional benefits I would receive?
Beyond funding, this opportunity offers meaningful strategic advantages:
Government Validation and Credibility:
Winning a U.S. Air Force award signals strong technical credibility and alignment with national defense priorities, which can accelerate partnerships with primes, integrators, and federal customers.Enhanced Market Visibility and Notoriety:
Awardees gain exposure within DoD ecosystems and innovation networks, positioning the company as a trusted provider of mission-critical technology.Follow-on Contract Opportunities:
Successful prototype efforts may lead to follow-on production contracts or expanded agreements without further competition.Stronger Exit and Acquisition Potential:
Demonstrating validated DoD use cases and maturing technology with nondilutive funding can significantly increase enterprise value and acquisition attractiveness.
What is the timeline to apply and when would I receive funding?
White papers can be submitted on a rolling basis until August 15, 2026
Full proposals are submitted only upon government invitation
Awards may be issued at any time through September 30, 2026
Where does this funding come from?
This funding comes from the U.S. Department of Defense, specifically the Department of the Air Force, under the Defense Commercial Solutions Opening Pilot Program authorized by Congress.
Who is eligible to apply?
Open to all organizations capable of delivering innovative solutions, including:
Startups
Small businesses
Non-traditional defense contractors
Large enterprises
Foreign participation is permitted, subject to security requirements
What companies and projects are likely to win?
Demonstrate breakthrough innovation rather than incremental improvements
Address critical or urgent Department of Defense needs
Show strong technical feasibility and a clear execution plan
Align with Air Force mission priorities and capability gaps
Provide pricing that is fair and reasonable
Are there any restrictions I should know about?
A White Paper is required before submitting a full proposal
Full proposals are by invitation only
Must comply with DoD security requirements and classification guidelines
Export control regulations (ITAR/EAR) may apply
Conflict of interest rules apply for certain contractors
How can BW&CO help?
Our team specializes in complex federal R&D proposals and can:
Triple your likelihood of success through proven strategy and insider-aligned proposal development
Reduce your time spent on the proposal by 50–80%, letting your team focus on technology and operations
Ensure you are targeting the best opportunity for your project and positioning your company for long-term growth.
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
FAA - BROAD AGENCY ANNOUNCEMENT AVIATION RESEARCH 2025
Deadline: Rolling Submissions
Funding Award Size: $400k
Description: Apply for FAA Aviation Research 2025 funding through a rolling BAA. Awards up to $400K/year for aviation R&D across pavements, AI/ML, flight systems, and safety technologies.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
This FAA Broad Agency Announcement (BAA) is an open, rolling opportunity to submit white papers for aviation research topics. There is no fixed deadline—white papers may be submitted at any time until the expiration of the BAA or until a Topic is removed.
If you are developing technologies in airport pavements, aircraft structures, propulsion, avionics, AI/ML, or safety systems, this is a flexible entry point to secure non-dilutive R&D funding. Because submissions are accepted on a rolling basis, strong teams can engage early and iterate with the FAA.
How much funding would I receive?
Funding varies by topic. Examples explicitly stated include:
Many topics:
Not to exceed $200,000.00 per project, per fiscal year
Some topics:
Approximately $250,000 per project, per fiscal year
Approximately $350,000 (total)
Not to exceed $400,000.00 per project, per fiscal year
In several topics:
Funding is not specified and will be determined based on the proposed work
All funding is:
Subject to availability
Typically awarded annually
What could I use the funding for?
Funding supports aviation R&D aligned with FAA priorities, including:
Airport pavement research (e.g., cracking, materials, instrumentation, modeling)
Structural integrity of aircraft components
Propulsion and fatigue testing (e.g., nickel alloy anomalies)
Flight controls, avionics, and safety systems
AI/ML applications in aviation systems and certification
Software tools and engineering models (e.g., FAARFIELD, BAKFAA)
Oversight systems, safety management, and regulatory innovation
Projects generally include:
Research, testing, and data analysis
Modeling and simulation
Software/tool development
Field validation and implementation planning
Are there any additional benefits I would receive?
Direct engagement with FAA technical teams and subject matter experts
Opportunity to influence FAA standards, Advisory Circulars, and software tools
Access to FAA datasets, test facilities (e.g., NAPTF), and research infrastructure (where applicable)
Potential for follow-on work based on performance and results
What is the timeline to apply and when would I receive funding?
Submission timeline:
White papers may be submitted at any time until the expiration of the BAA or until the Topic is removed
Project duration:
Many topics allow up to 3 years
Some specify 12 to 36 months or 24 months
Others: not specified
Funding cadence:
Typically annual funding, subject to availability
Continued funding is at FAA discretion based on performance and results
Award timing:
Not specified in the solicitation
Where does this funding come from?
Federal Aviation Administration (FAA)
Specifically through the William J. Hughes Technical Center for Advanced Aerospace
This is a Broad Agency Announcement (BAA) for aviation research.
Who is eligible to apply?
Eligibility is not explicitly specified in the provided text
The solicitation refers broadly to:
“Offerors”
“Aviation community”
Entities capable of submitting white papers aligned to technical topics
What companies and projects are likely to win?
Based on the solicitation, competitive projects will:
Directly address a specific Topic of Interest
Demonstrate technical feasibility and research rigor
Leverage real-world data, FAA datasets, or test facilities
Align with FAA implementation goals (e.g., integration into FAARFIELD, Advisory Circulars)
Show clear pathways to improving safety, performance, or certification processes
Incorporate advanced methods (e.g., AI/ML, modeling, novel instrumentation) where relevant
Projects that connect research outputs to practical FAA use cases are strongly aligned.
Are there any restrictions I should know about?
Submissions must be in the form of white papers aligned to specific Topics
Work must follow instructions and evaluation criteria in the BAA
Some topics include specific constraints, for example:
Avoiding proprietary system promotion in certain research areas
Compatibility with FAA systems or software environments
Funding is:
Subject to availability
At FAA discretion based on performance and results
No universal restrictions (e.g., cost share, TRLs) are specified in the provided text.
How long will it take me to prepare an application?
The solicitation requires brief descriptive white papers
Estimated effort will depend on complexity, but:
White papers are typically faster to prepare than full proposals
Exact preparation time is not specified in the solicitation
How can BW&CO help?
BW&CO can:
Identify the best-fit FAA Topic(s) for your technology
Translate your innovation into a compliant white paper aligned to FAA expectations
Position your work for implementation into FAA standards, software, or guidance
Help structure a phased engagement strategy to maximize follow-on funding
Ensure your submission is clear, technically credible, and aligned with evaluation criteria
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
Army DEVCOM: BAA for CBRNE Defense Efforts Under Procurement Contracts, Cooperative Agreements, and Prototypes under OTAs.
Deadline: Rolling White Paper Submissions
Funding Award Size: $500k -$5m
Description: The DEVCOM CBC Broad Agency Announcement supports CBRNE defense R&D across biosensors, aerosol tech, biodetection, decontamination, protective systems, AI/ML, advanced materials, and related mission areas.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
This is a continuously open Broad Agency Announcement (BAA) from the U.S. Army DEVCOM Chemical Biological Center (CBC) seeking innovative R&D in CBRNE defense. There is no fixed deadline—submissions are accepted on a rolling basis for up to five (5) years.
Founders should act quickly: while submissions are always open, funding availability is uncertain and awards are made competitively as needs arise. Early engagement via preproposals is strongly encouraged.
How much funding would I receive?
Not specified in the solicitation, but typically will lead to awards between $500k - $5m.
Budgets must be commensurate with the scope and complexity of the proposed work
At the time of publication, no funds are specifically allocated, and awards depend on availability of funds
What could I use the funding for?
Funding supports basic research, applied research, and advanced development in CBRNE defense.
MISSION AREAS:
1. SENSOR TECHNOLOGIES AND BIOMATERIALS: DEVCOM CBC is exploring biotechnology concepts in the areas of detection and decontamination of chemical biological (CB) agents, environmental biodegradation and bioremediation, and novel biotic materials. Areas of interest are:
a. Enzymatic systems for the degradation of chemical nerve agents, mustard and toxins, biological warfare agents and related materials, and investigation of self-decontaminating coatings that have enzymatic or biochemical components. Emphasis is on enzymology, protein chemistry, and molecular biology.
b. Investigation of microbial systems, biosurfactants and other natural products for the bioremediation of hazardous wastes including chemical agents, their precursors or products, obsolete decontaminants, and other chemical weapons/warfare (CW) related materials. Emphasis is on bioengineering and fermentation.
c. Nanobiotechnology, principally the rational biomolecular and nano-system design of functional abiotic structures; reconfigurable self-organizing systems; novel nanoparticles; or supramolecular self-assembly; including but not limited to, materials for nanoparticles, nano and meso scale materials fabrication and assembly, and miniaturized devices. Focus is on supporting the Army's zero maintenance efforts and minimizing weight, size, power, and energy requirements.
d. Next generation reagents including, but not limited to, aptamers, polymers, and peptides with novel binding, catalytic or structural properties. Areas of interest include, but are not limited to, gene libraries, tissue based biosensors, molecular signaling and novel transduction techniques.
e. Studies on metabolic engineering, optimizing and modeling bioreactor conditions for the scale-up biomanufacture of recombinant and other proteins in bacterial and insect cell systems. The products include, but are not limited to, recombinant antibodies, enzymes, and simulants. Studies may include optimizing feeding strategies, sterilization kinetics, and other bioreactor parameters to increase yield and decrease cost, as well as cryopreservation.
f. Molecular toxicology with emphasis on gene arrays, specifically the exploitation of recent advances in “panomics"; which refers to genomics, transcriptomics, proteomics and metabolomics, bioinformatics and in vitro approaches such as, but not limited to, cytosensor microphysiometer studies.
g. NOTE: The following in‑house equipment is available for possible use:
(i). Large-scale fermentors and hollow fiber bioreactors.
(ii). Gene array printer.
(iii). Analytical (capillary electrophoresis, gas chromatographs, high pressure liquid chromatographs, UV/visible spectrophotometer, microplate reader, total organic carbon analyzer).
(iv). Protein purification (high‑speed centrifuges, gel electrophoresis, low pressure chromatograph, high pressure liquid chromatographs, cell disruption systems).
(v). Molecular biology (automated DNA sequencing and synthesis, polymerase chain reaction, gel electrophoresis).
(vi). Bacterial culture (autoclaves, incubators, incubator shakers, 1 to 1500 liter fermentation systems, centrifuges, cell disruption systems).
2. AEROSOL TECHNOLOGY: The objective of the aerosol technology program is to develop advanced aerosol sampling devices needed for detection systems, and to provide the necessary experimental facilities, capabilities (instrumentation and personnel), and methodology to support experimentation with aerosol devices for all DEVCOM CBC mission and customer programs, emphasizing bioaerosols in the near term. A major effort under this program involves developing the capability to provide quantitative capability to experiment with biosimulant aerosols including controlled generation (size, low concentrations, high rates for high speed wind tunnel studies), quantification, and characterization of laboratory instruments, field experiments, and military devices. The DEVCOM CBC is interested in innovative concepts to address the following areas of study:
a. Effective, Efficient Aerosol Collectors. Theoretical studies of the design and employment of highly biased aerosol collectors intended to collect particles in the 1 to 10 micrometer diameter size range. Fabrication and delivery of such devices which will collect into a small volume of liquid (1 milliliter), or concentrate into a small volume air stream, aerosol particles from 100 to 10,000 liters per minute using little power (nominally 10 to 20 watts) with collection efficiencies exceeding 80% in the 1 to 10 micrometer particle size range. A goal is to minimize the size and weight of the device.
b. Method of generating narrowly dispersed aerosols (log standard deviation = 1.5) from slurries or bulk powders. Aerosol mass median diameter selectable over the range of 0.2 microns to 45 microns.
c. Investigation of collection efficiency and effects on the viability of biological materials, e.g., Bacillus atrophaeus (BG) and Erwinia herbicola, when collected from the aerosol state by various collection means to include impaction, vortex scrubbing, electrostatic precipitation, and filtration. Research and investigations to develop technologies for sampling viable microbes from the atmosphere to include processes which consider such factors as relative humidity, repair mechanisms, and other environmental considerations which influence the survival of microbes in the open air. A new device that considers these factors will be expected to have a higher survival rate for microbes and a greater efficiency. These investigations will lead towards a new device for sampling environmental air samples.
d. Low energy methods and devices for concentrating suspensions of 1 - 10 micron particles in liquids such as water or phosphate buffered saline from milliliters to microliters with high efficiency for retaining the particles in suspension in the reduced volume.
e. Dissemination of bulk powders into the inherent particle sizes found in the feedstock. Dissemination rates of 10 to 250 grams per minute.
f. Methods for near real-time field sizing of large polydisperse aerosols (20-500 micron operational range) that are disseminated from high volume aerosol generators such as crop dusters or "leaf blower" type devices.
g. Aerosol wind tunnel methodologies for creating well-mixed, spatially and temporally uniform challenges of monodisperse inert aerosols and polydisperse biological simulant aerosols for wind speeds up to 80 miles per hour. Aerosol wind tunnel methodologies for creating temporally uniform challenges of monodisperse liquid droplets that can convey inert and biological simulant aerosols for feed rates up to 50 grams/minute.
h. Design, and/or fabrication, and/or testing of omnidirectional aerosol inlets with aspiration efficiencies greater than 80% for aerosol particles over the aerodynamic diameter size ranges 1 to 10 micrometers (with strong rejection of particles > 10 micrometers) and 1 to 25 micrometers from air flows at wind speeds from 2 to 50 miles per hour. A family of inlets are required covering the internal (aspirated) flow rates from 1 liter per minute to 10,000 liters per minute.
i. New optical methods for characterizing aerosols for CB detection, smoke development, and field test programs. In particular, the use of Mueller matrix scattering and optical spectroscopic signatures from bacterial cells to correlate changes in biological parameters with changes in scattering pattern and optical methods which can be used as aerosol detectors, such as particle scattering, fluorescence, etc.
j. Innovative approaches using computational fluid dynamics to describe the external and internal flow around and through vehicles, detectors, sampling ports, buildings, etc., in the open and in wind tunnels (to include analysis of wall effects). The approach or method can use the finite difference or finite element techniques. The description of the flow field should include streamlines, velocity fields, and pressure distributions and allow for modeling of (size‑dependent) aerosol particle trajectories.
k. Methods for laboratory handling, examination, and analysis of single aerosol particles, including spectroscopic methods, and the study of chemical reactions in single particles.
NOTE: Extensive in-house laboratory facilities and equipment are available for possible use, including state-of-the-art aerosol generators, aerosol analyzers, aerosol chambers, and aerosol wind tunnels.
3. BIOLOGICAL POINT DETECTION: The DEVCOM CBC has initiated an effort to investigate commercially available and developmental technologies for the detection and identification of agents of biological origin. This effort will result in automated sensors capable of detecting and identifying these agents in air, food, water or surface samples. Research areas of interest are:
a. Adaptation of existing commercial macroscale, mesoscale, and microscale biosensor platforms or development of such biosensors to detect and/or identify agents of biological origin in the field. Emphasis is placed on sensors with simple, rapid, reliable assay formats that utilize immunological or DNA/RNA based assay approaches as well as non-immunological or non-DNA/RNA based biosensors using novel/alternative assay approaches.
b. Assessment, adaptation, or development of immunological based biosensor technologies that provide rapid and simultaneous multiplex and/or multiagent array based detection and identification for agents of biological origin. The main focus is the interrogation and/or development of technologies that meet biodetection requirements for higher throughput, faster immunodetection, and simultaneous analysis of multiple agents with good assay sensitivity while preserving specificity. Candidate systems must be small, lightweight, and user friendly. Assay chemistries should be robust and evaluated for eventual dry down into a simple, single-use reagent format.
c. Development and evaluation of sample preparation methods for subsequent immunological based analysis, and identification, modification, and assessment of commercial and developmental hardware that is capable of front-end sample clean up and sample concentration from sample matrices compromised by environmental, animal, or plant substances. Emphasis is to identify and perform separation of bacteria, spores, and toxins from compromising sample matrices using Immunomagnetic Separation (IMS), affinity, and other capture methods. Identify automated approaches and hardware for higher throughput. The methods must be capable of concentrating milliliter to liter volumes down to sub-milliliter to low milliliter amounts, respectively.
d. Integration, implementation, and validation of analytical instrumentation and procedures for development of robotic based, high-throughput, portable, and automated total analysis biodetection systems (i.e. sample preparation, biodetection, subsystem reset, and decontamination) for use in deployable mobile laboratories or expanded bioanalysis programs. Emphasis is to design the process for sample analysis using immunoassay or polymerase chain reaction (PCR) based analysis systems.
e. Development of rapid, automated, lightweight, and portable sensor technologies to be used in the identification of bioagents based on both protein and nucleic acid targets with emphasis on the use of labless detection and identification approaches, reusable capture substrates and transduction surfaces, and minimal footprint and power.
f. Development of rapid and automated RNA/DNA detection and identification technologies and assay methods that will allow for both the production of a library of amplified targets from a single set volume of an environmental sample, and the probing of that library for identification of all targets of interest, all in a single analytical method. Current methods using methods such as random hexamers, PCR/RT-PCR, or multiplex assays may be inadequate due to reagent exhaustion prior to completion of the library and its analysis. Standard PCR and RT-PCR would deplete sample volume long before the analysis is complete for all targets of interest.
g. Development of rapid, automated, and portable technologies to rapidly concentrate and remove interfering substances from liquid environmental bioagent samples, and prepare the targets of interest for nucleic acid analysis. The methods must be capable of concentrating milliliter to liter volumes down to sub-milliliter to low milliliter amounts, respectively; delivering a concentrated amount of nucleic acid material for analysis. Emphasis is on minimizing nucleic acid sheering.
h. Development and testing of rapid, lightweight, automated, user friendly, and portable biosensor platforms that are capable of performing both nucleic acid and immunoassay based detection and identification of bioagents (i.e. both operations taking place on one sensor). Emphasis is given to approaches that provide simultaneous detection and identification of multiple bioagents (e.g. array based), and simultaneous immunological and nucleic acid based analysis. However, consideration will also be given to systems that perform the two types of assays sequentially as well as sequential detection and identification.
i. Formulation of either established or new and innovative protocols of bacterial biochemical marker extraction into simple and convenient recipe driven procedures. Limitations on the length of time, number of manipulation steps, use of nonhazardous compounds and solvents, low salt concentration, and the potential for automation must be considered in the proposed approaches.
j. Development of automated bacterial biomarker extraction devices. The output stream should be amenable to being delivered by analytical sample transfer or introduction systems into analytical detection systems. Weight, size, power and amount of consumable(s) of the proposed microorganism biomarker extraction system(s) should be geared to a minimum. The offeror should also address the fabrication of a system in a number of generations, from first prototype to advanced prototype systems.
k. Mass spectrometry methods are sought that will allow laboratory and field determinations of the feasibility of mass spectrometry concepts for biological organism detection.
l. Development of databases to facilitate detection and identification of bacteria, viruses and toxins.
m. Integration of automated bacterial biomarker extraction with electrospray and/or matrix assisted laser desorption ionization mass spectrometers.
n. Downsizing mass spectrometry hardware, reducing power requirements, increasing processing speed for rapid detection and identification of biological organisms.
o. Conceptualization and validation of alternative means of vaporizing or ionizing biological aerosols without collection on a substrate or probe.
p. Development of a database of Raman spectra of biological materials.
q. Enhanced concepts of using lasers in CB defense, including, but not limited to, laser desorption, surface catalyzed laser decomposition, surface enhanced laser ionization, and single particle UV fluorescence and mass spectrometric techniques (primarily for the detection of biological materials). Specific interests include enhancement of matrix-assisted laser desorption ionization mass spectrometry through improvements in mass resolution, sensitivity and on‑line incorporation of analytical separation techniques.
r. The use of small, powerful lasers for use in flow cytometry.
s. The development of new dyes, immunoassay reagents, nucleic acid probe reagents, etc., for the enumeration of bacterial properties. Ideally these materials should be excitable with red diode lasers, although dyes excited with argon ion or other lasers are also of interest.
t. Simple bioluminescence/chemiluminescence equipment.
u. Development of improved data processing techniques in flow cytometry, such as neural nets, expert systems, etc.
v. Investigations into the mechanisms of biological aerosols, such as factors affecting viability and culturability; preservation of activity; and effects of particle sizes on viability.
w. Fusion of generic detection capabilities, such as particle size analyzers, elemental analysis, or organic composition with computer algorithms to affect a smarter detection capability.
x. Investigations into virus detection techniques.
y. Simple, rapid tests for the determination of sugars, proteins, nucleic acids, etc.
NOTE: Use of DEVCOM CBC instrumentation (on an availability basis) and flow cytometers may be granted.
z. Collection and organization of current and historical biological reports and other literature for inclusion in the Biological Defense Encyclopedia. This effort will include the location of literature and reports and the electronic processing of these papers and images for addition to an existing database. This effort will be wide reaching in scope and will seek to include all available information on the historical, physical, and detailed microbiological information regarding microbes considered of use in biological warfare (BW). One use of this database is assistance to defensive models and research governing the detection of microbes in the environment.
aa. Remote, stand‑alone systems are needed that are capable of triggering for the presence of biological compounds and microorganisms. Pyrolysis gas chromatography-ion mobility spectrometry (Py-GC-IMS) and Pyrolysis-gas chromatography-small mass spectrometry (Py-GC-MS) are candidate systems because of their relatively small size and logistics. The system can also provide information for specific pyrolyzate compounds from biological material. Technologies must demonstrate short duty cycle times; a logistically efficient, low power burden aerosol collector; efficient transfer of pyrolysis products to the ion mobility spectrometry detector; and distinct gas chromatography/ion mobility spectrometry dataspace domains corresponding to established compounds found in microorganism and protein biological compounds.
NOTE: The following in-house equipment is available for possible use for the remote, stand-alone systems:- Py-GC-IMS briefcase platform- 200 C/min and 6000 C/min Thermogravimetry (TGA)-GC-MS systems.- Py-GC-parallel IMS- time of flight MS.
bb. Algorithm for generating mass spectrometric libraries for protein toxins, bacterial and viral particles; search routines for automated comparison of sample and standard mass spectrometry spectra and automated identification of biological agents.
cc. Studies to expand and analyze data bases of ambient biological aerosol background, to include particle counting and sizing, enumeration of major microbial constituents, quantification of biological loading in the ambient atmosphere, and correlation of these characteristics with meteorological conditions, season, diurnal period, etc.
dd. Optical Trigger Technology. Spectroscopic interrogation and analysis of aerosol particles for peculiar signatures "fingerprints" that facilitate rapid screening and continuous monitoring of ambient air for the likelihood of a BW agent event. The purpose of the trigger is to provide adequate early warning to friendly forces and cue a collection and assay system for confirmation and identification of the biological threat.
4. CHEMICAL POINT DETECTION:
a. Lightweight Detection: The DEVCOM CBC has initiated an effort to investigate technologies with potential for detection and identification of Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) hazards using small, lightweight, modular devices. This effort will result in development of devices capable of detection of less than incapacitating levels of agents in real-time where real-time is defined as a few seconds. Devices must also be able to recover from an exposure in a similar amount of time. Technologies must demonstrate potential for development into devices with the following desirable characteristics: fit into shirt pockets of battle dress uniforms, weigh less than two pounds, and consume less than two watts of electrical power. Technologies must also demonstrate potential for exhibiting ultra-sensitivity properties, defined as miosis levels of CW agent poisoning, within a few minutes using minimal electrical power. It is also desirable that ultra-sensitivity properties result from addition of a small, lightweight modular form of sensitivity enhancement onto the real-time detection device.
b. Mass Spectrometry: The DEVCOM CBC is interested in innovative concepts in the following areas, all related to the potential use of mass spectrometry to detect, identify and quantify chemical and explosive hazards:
(i). Design of a mass analyzer and efficient algorithms for rapid analysis of mass spectra of CB agents.
(ii). Incorporation of artificial intelligence techniques for optimization of spectrometers for the detection of CBRNE hazards.
NOTE: In‑house development environments available for possible use include Matlab, Mathmatica, PC‑Based Expert Systems technology, as well as conventional non-artificial intelligence computer languages. Extensive laboratory computing facilities, including multiprocessor mini-supercomputers, are also available.
c. Investigation of the application of fluorescence, Raman, infrared, and terahertz spectroscopy for the detection of chemicals on natural and man-made surfaces.
d. There is a need for a remote stand‑ alone detector to trigger and/or detect CB species. Candidate components of ion mobility spectrometry‑based methods include:
(i). Hydrophilic and hydrophobic solvent extraction techniques for relatively large biological substances from bacteria.
(ii). On‑line filtration so as to remove salts and signal suppression compounds.
(iii). Liquid‑based techniques for the separation of biological compounds within a molecular weight range.
(iv). Electrospray ionization in order to efficiently transfer the biological compounds into an ion mobility spectrometer.
(v). Data analysis techniques and ion mobility spectrometer tandem mass spectrometry to correlate the observed signal with known biomarkers.
(vi). The system shall also produce information from chemical agents in aqueous solution at concentrations less than parts-per-million levels. The sensitivity goal is low parts-per-billion. Both BW and CW information production from the electrospray ionization ion mobility spectrometer system shall display high sensitivity, low liquid expendable logistics and efficient clearing of the ion mobility spectrometer detector.
e. Development and/or modification of new or existing methodologies for the detection and identification of low levels of both chemical and biological hazards in water sources.
5. EARLY WARNING AND DETECTION: The DEVCOM CBC has initiated an effort to investigate commercially available and developmental technologies for early warning, detection and identification of chemical, biological, radiological, nuclear and explosive hazards. This effort will result in automated sensors capable of detecting and identifying these agents in air, food and water or surface samples. This effort will focus on standoff technologies where a sensor is physically separated from the CBRNE hazards by some distance. Research areas of interest are:
a. Adaptation of existing standoff sensors or development of novel standoff sensors to detect, identify, and/or quantify chemical, biological, radiological, nuclear and explosive (CBRNE) hazards in the field. Emphasis is placed on optical sensors that provide sensing at a distance and provide detection and reconnaissance over a wide area of a possible battlefield. However, other techniques such as acoustical sensing will be examined also.
b. Investigation of new and novel spectroscopic techniques for proximal and/or standoff detection, identification, and/or quantification of CBRNE hazards. All regions of the electromagnetic spectrum, from radio waves to g-rays, will be explored. New spectral methods for the discrimination of CBRNE hazards from possible interferents, i.e. methods that increase detection sensitivity while reducing false alarms, are sought. Both active and passive technologies will be explored.
c. New methods for wide area detection are sought. Wide area detection requires the simultaneous monitoring of large areas of a battlefield for CBRNE hazards.
d. New and novel signal processing for standoff CBRNE detection is being sought. Sensor integration will also be examined.
e. New excitation sources for standoff detection will be examined. New laser sources for CBRNE detection are being sought. Better sources in other regions of the electromagnetic spectrum, such as the deep ultra-violet, far infrared and millimeter wave regions, are also being sought.
f. New methods for detection-on-the-move are sought. Placing a standoff sensor of a moving platform requires care. This effort will focus on developing sensors that are rugged and can operate rapidly such that movement of the vehicle does not blur the signal from the sensor.
g. New methods are sought for standoff detection of aerosols.
h. New methods are sought for standoff detection of contaminants on surfaces, both natural and manmade.
6. SMOKE AND OBSCURANTS: The objective of the smoke program is to develop materials and demonstrate weaponization feasibility to provide full spectrum screening (as required) to defeat or degrade threat target acquisition, ranging and marking, tracking, anti‑tank guided missiles, and directed energy weapon systems. A major effort under this program involves developing the capability to provide effective obscuration in the UV, visible, IR, and microwave regions of the electromagnetic spectrum. Combinations of these four regions (multi-spectral) are also of interest. The DEVCOM CBC is interested in innovative concepts to address the following areas of study:
a. High yield visual, IR and microwave obscurants on the battlefield.
b. Dispersion technology for nanoparticles (conductive flakes and fibers).
c. Improved screening material packaging, compaction, feed, and deagglomeration technologies.
d. Visual, IR and microwave obscurants that are environmentally safer and/or less toxic than current materials.
e. Identification of candidate multiband screening material.
f. Improved dissemination of materials.
g. Improved ballistic stability of non-solid payloads.
h. Techniques to measure screening effectiveness and obscurant generating equipment effectiveness.
i. Aerosolization of obscurant materials.
j. Effects of smokes and obscurants on the battlefield.
k. Vulnerability analysis of threat sensor systems versus obscurants.
l. Additional Requirements. Innovative concepts are requested to address requirements for the following future obscurant systems:
(i). Nanoparticle obscurant candidates (ultrathin conductive flakes or submicron-diameter conductive fibers that can be aerosolized)
(ii). Degradable smokes, i.e., a limited life obscurant that does not interfere with future battlefield operations.
(iii). Robotic delivered smokes.
(iv). Smoke clearing concepts.
(v). JP‑8, the single fuel to be used in future battlefield operations, does not produce an effective smoke screen in the Vehicle Engine Exhaust Smoke System. Improved duration and persistence of JP‑8 smoke is needed.
(vi). Spectrally-selective obscurants.
NOTE: Facilities at DEVCOM CBC that are available for possible use include: A 190 cubic meter aerosol chamber for analyzing small obscurant samples (10 to 100 grams). It is equipped with instrumentation for measuring transmission for the range 200 nanometers to 15 centimeters (UV to microwave). Concentration of the aerosol can be measured for calculating extinction coefficient. Various dissemination devices are available.
A breeze tunnel for testing particulate disseminators up to full‑ scale generators. It has a 14-foot by 14-foot cross-section, a 100,000 cubic feet per minute flow rate and a 5-mile per hour wind speed. It has laser and background action required radar transmissometers (.63 microns, 10.6 microns, 35 gigahertz, 94 gigahertz) for evaluating dissemination efficiency. It has the capability to take samples of the obscurant.
7. MODELING, SIMULATION, AND ANALYSIS FOR CB, SMOKE, AND OBSCURANTS: The objective of this program is to design, develop, validate and utilize analytical and computer modeling and simulation tools to analyze CB agent and smoke/ obscurant cloud transport and diffusion; agent deposition; performance of CB defense equipment; and performance degradation effects on personnel and equipment due to CB agents and smoke/obscurants. The program is oriented to constructive and virtual implementations in the Distributed Interactive Simulation (DIS) and High Level Architecture (HLA) environments. The program is supported by the following tasks:
a. Characterize the CB/smoke warfare environment for support of CB defensive equipment research, development and acquisition including test and evaluation. Of special interest is constructive and virtual DIS/HLA environments as relates to effects on performance of personnel and CB defense equipment.
b. Characterize the performance of CB/smoke defensive equipment in a contaminated environment. Of special interest are point and standoff detectors, individual and collective protective gear, decontamination processes, warning and reporting systems, and command and control processes in a DIS/HLA environment.
c. Characterize the fate of CB agents deposited on surfaces such as soil, water, foliage, metal, roadways, runways, ships, buildings, military equipment, and electronic devices.
d. Characterize and validate CB and smoke/ obscurant cloud transport and diffusion under conditions of variable meteorological conditions, terrain formations, around and within various types of buildings and structures in urban and military locations. Work should be specifically oriented toward the DIS/HLA environment and be interoperable with existing DEVCOM CBC DIS simulations and simulators like the Chemical, Biological, and Radiological Simulator.
e. Characterize the effectiveness of smoke and obscurants for development, training and operations as well as for countermeasures to smart weapons with emphasis on DIS/HLA.
f. For all of the above areas of research, assist in the archiving, retrieval and analysis of historical data for the generation of model algorithms and determination of improved model input parameters. Key aspect is the publishing of the historical data in formats or databases that are widely accessible both within DEVCOM CBC and external organizations.
8. COLLECTIVE PROTECTION: The objective of the collective protection program is to develop new and improved concepts, methods and materials for collective protective systems to guard against all potential threat agents. Future collective protection will be modular in design with lower power, weight and size requirements and longer operational life. Future systems will be integrated with the host's environmental control unit and/or auxiliary power unit. Current efforts involve developing new concepts and improved materials and processes for enhancing and/or providing an alternative to present impregnated activated carbon based collective protection systems. Emphasis will be on greatly extended operational life and reduced logistics burden. Current concepts being considered include, but are not limited to: regenerative filtration using pressure swing adsorption; temperature swing adsorption; a new improved sorbent technology; membrane technology; and, new and improved canisters and filtration media. With this in mind, the DEVCOM CBC is interested in the following innovations:
a. Concepts for studying the vapor adsorption properties of standard ASZM‑TEDA (chromium free) carbon and of developmental fixed‑bed adsorptive reactive media and processes such as pressure and temperature swing adsorption, membrane separation, and catalytic oxidation.
NOTE: The following equipment is available for use under this area of interest:
(i). Surface analysis instrumentation.
(ii). CATOX reactor/data acquisition systems.
(iii). Lab‑scale pressure swing adsorption (PSA) reactor/data acquisition systems.
(iv). Adsorption equilibrium measurement systems.
b. New air purification technologies that provide enhanced CB removal capability with low power requirements while also offering the advantages of small size and low weight.
c. New aerosol filtration technologies that provide improvements in the following areas over that provided by filters based on high efficiency particulate air grade media:
(i). Increased filtration efficiency
(ii). Lower pressure drop
(iii). Reduced clogging
d. New adsorbent technology applicable as a substrate for impregnation for use in current reactive adsorber systems or as an adsorbent for use in pressure swing adsorption or temperature swing adsorption systems.
e. New reactive impregnant technology that provides increased chemical warfare agent removal for application on an adsorbent substrate (either carbonaceous or non-carbonaceous).
f. Improvements to current filter and ancillary equipment designs (both for collective protection and for use on respirators) to provide benefits in performance, physical characteristics and/or costs (item and operational).
g. Improvements to equipment that permits safe and rapid entry and exit to or from collective protection shelters.
9. RESPIRATORY PROTECTION: The main objective of the respiratory protection program is to develop new and improved concepts, test methods, and materials for respiratory protective systems to guard against all potential CBRN threat agents while minimizing the impact on mission performance. Future respiratory protection will be modular in design with lower profile and weight requirements to improve equipment compatibility and reduce the physiological burden and discomfort often associated with respirator wear. Current efforts involve developing novel integrated CBRN-protective mask and headgear (i.e., helmet) concepts that provide enhanced respiratory protection, comfort, and compatibility with heads-up displays, communication equipment, weapon sighting systems, and other individual protective clothing and equipment worn by the warfighter. Innovative air-management systems, real-time mask fit indicators, seal designs, and other technologies are being sought that offer significant advances in the protection, fit, operational performance, and comfort of the mask system. In addition, the DEVCOM CBC is interested in enhancing its facilities and methodologies needed to support experimentation with next generation respiratory protective devices for all mission and customer programs. Research areas of interest include:
a. Development and demonstration of closed-circuit self-contained breathing apparatus concepts and test bed systems, including hybrid systems consisting of powered air purification. Investigation of associated technology for weight and heat reduction and improvements in efficiency.
b. Design and fabrication of integrated respiratory protection headgear concepts and test bed systems. Development of new and innovative integration approaches, attachment systems, and sealing systems.
c. Fabrication of respiratory protection prototypes for operational demonstration. Application of rapid prototype and manufacturing technology to fabricate robust and functional prototype models.
d. Investigation of nano-scale material solutions for respiratory protection. Exploration of material and coating technology to enhance CBRN protection, lens fogging resistance and seal performance.
e. Investigation of microelectromechanical solutions (i.e., MEMS technology) for respiratory protection. Exploration of novel MEMS and other smart technology solutions for breathing assist, cooling, sealing systems, and other respirator operational parameters of interest.
f. Assessment of concurrent CBRN PPE wear on ballistic PPE effectiveness. This effort will initially assess the applicability of current ballistic helmet standards to evaluate concurrent CBRN PPE usage. Develop new or improve existing test methodologies and obtain data to assess the effect of concurrent wear on all parameters of ballistic helmet performance (e.g. stability, shock, and surface coverage).
g. Develop new or improve existing unmanned test systems, test equipment, test methods and procedures for human factors assessment of respiratory protective masks including, but not limited to, field of vision, eye relief, fogging, breathing resistance, speech, hearing, and sweating.
h. Scale metal-organic frameworks to kilogram and above quantities. Develop flow-through and/or solvent recycle systems to increase yield and drastically reduce cost compared to current methods. Reduce the need for organic solvents. Develop techniques for supramolecular engineering of large mesh metal-organic frameworks through strategies such as binding and polymerization. Focus should be on metal-organic frameworks with military utility. These materials can be used for applications such respiratory protection, filtration, suits, decontamination, etc.
10. DECONTAMINATION: An objective of this program is to understand, develop, mature, or otherwise advance decontaminant technologies and approaches through the characterization of contaminant-material-decontaminant-environmental interactions.
a. Development and demonstration of novel decontaminant formulations for chemical and biological decontamination.
b. Modeling and Simulation tools and techniques as applied to Decontamination Sciences: design, develop, validate and utilize analytical and computer modeling and simulation tools to analyze/characterize contaminant, material, decontaminant, environmental interactions.
c. Demonstration of dual use technology with application to chemical/biological agent decontamination and routine cleaning/maintenance activities.
d. Analytical tools and techniques to advance the characterization of contaminant, material, decontaminant, environmental interactions.
e. Development and demonstration of coatings/surfaces with enhanced resistance and/or inherent reactivity toward chemical contamination.
f. Application and optimization of novel solids for sorbent/surface decontamination.
g. Application and optimization of vapor/gaseous decontaminants for chemical and biological agents.
h. Innovative technologies are sought to support development for the sensitive equipment decontamination (SED) program. Technologies are needed to decontaminate (safe removal and/or destruction) chemical and biological warfare agents from sensitive equipment and vehicle interiors without adversely affecting the function of the equipment and/or interior components. The SED program is currently seeking technologies/processes for two capability segments. The first is the decontamination of vehicle, ship and aircraft interiors. The second capability is to decontaminate vehicle, ship, aircraft interiors and associated cargo during operation. These technologies or systems are needed to meet one or both capability segments.
11. CHEMICAL, BIOLOGICAL, RADIOLOGICAL, NUCLEAR, AND EXPLOSIVES COUNTERMEASURES TO TERRORISM: The DEVCOM CBC is seeking proposals for novel research to assist in the war against terrorism. This is a broad research area, and proposals topics include (but are not limited to): biological and chemical countermeasures, CBRNE sensor and detector development, rapid methods of CBRNE detection, new and advanced decontamination techniques, new physical and protective countermeasures, technology enhancements for first responders, advances in hospital response, chemical and biochemical agonists and blocking agents, advanced biotechnological methods, rapid diagnostic methods, new CB training and communication procedures and CB modeling and simulation methods.
12. FLAME AND INCENDIARY TECHNOLOGY: The DEVCOM CBC is seeking proposals for novel research in flame and incendiary technology. This is a broad research area, and proposal topics include (and are not limited to) enhanced reactive materials, thermally enhanced hydrocarbons, pyrophorics, hypergolics, intermetallics, thermobarics and thermite/thermates. The applications of these and other technologies may be uniquely delivered to enhance lethality of personnel and materiel targets. Such targets and situations include (and are not limited to) military operations in urban terrain, operations other than war, enhanced lethality to traditional materiel (e.g. vehicles) and fuel targets. Such delivery concepts include (and are not limited to) shoulder-launched systems, projectiles and grenades.
Non-traditional thermites are a class of reactions characterized by the incorporation of metal oxides that are unlikely to generate vapor phase products, such as titanium dioxide and silicon dioxide. However, such reactions can be sluggish in nature and risk quenching in many applications. Thus, their reactivity must be increased. Ball-milling and incorporating micron-sized refractive metals such as Zr, Ti, and Hf as well as adding boron to increase the heat of reaction. Al-Zr composites leverages the combination of zirconium's lower ignition temperature and aluminum's higher ignition temperature. This combination decreases the sensitivity of Zr only based reactions and lowers possible microexplosions found with Al based chemistries. The government is looking to characterize various refractive metal compacts of the metal oxide composites with a variety of analytic techniques that include, but are not limited to particle size analysis, pycnometry, X-ray diffraction (XRD), hyperspectral imaging and scanning electron microscopy (SEM). The objective is to determine basic information about these compacts. Formulations for the preparation of refractive metals samples will be identified and developed by the government. The government may also provide some samples for confirmation of production methodology.
13. EXPLOSIVES POINT, PROXIMAL, AND STANDOFF DETECTION:
a. The development and understanding of signatures and algorithms required to provide improved point, proximity, and standoff detection of explosives, homemade explosives and precursor materials to enable the warfighter to integrate chemical and explosive hazard detection equipment.
b. The collection and analysis of alternative chemical signatures and algorithms that will improve the probability of detection of an explosive hazard or homemade explosives (HME) manufacturing/assembly location. Additionally, signatures based phenomenology to improve point and stand-off detection of explosives and precursor materials.
c. Development of and integration into existing point, proximal and stand-off detection systems for explosives and homemade explosive precursor materials.
d. Forensics analytical methods for military explosives, HME, HME precursors, and residue analysis for attribution. (See Paragraph 7.16)
14. CHEMICAL FORENSICS: Forensic science is a multidisciplinary subject used for examining crime scenes and gathering evidence to be used in prosecution of offenders in a court of law. Forensic science techniques are also used to examine compliance with international agreements regarding weapons of mass destruction and counter-improvised explosive device (IED) operations.
a. Chemical Forensics for WMD attribution. DEVCOM CBC is interested in a growing area of forensic analysis for monitoring non-proliferation of weapons of mass destruction, analysis of possible terrorist attacks or breaches of security. The nature of samples analyzed is wide, but slightly different to a criminal investigation. Novel and new methods of sample collection and forensic analysis from objects, water, and plant material to test for the presence of radioactive isotopes, toxins, poisons, biological agents, and chemicals that can be used in the production of chemical weapons or homemade explosives.
b. Instrumentation. A number of orthogonal analytical methods are needed for forensic laboratories to analyze evidence. These methods vary and may not be appropriate for use in a combat environment by soldiers not performing a law enforcement mission. Many of these forward deployed teams rely on portable instruments. While these can perform rapid forensic analysis in the field, they are often limited in their capabilities, and have elevated false positive rates when compared to results from a fixed forensic laboratory. Instruments are needed for chemical analysis in austere laboratory or field conditions that provide reliable and complete chemical composition information. Additionally, new laboratory instruments are needed to identify nearly every element present in a sample.
15. CHEMICAL BIOLOGICAL ADVANCED MATERIALS AND MANUFACTURING SCIENCE:
a. The characterization of chemical, biological, physical, and fundamental properties related to surfaces, interfacial dynamics, thin film materials, chemical-biological catalysis, and opto-electronic/sensory technologies.
b. Modeling and analysis to provide an understanding of the characterization and behavior of chemical and biological phenomena occurring at or near solid surfaces and material interfaces to include transport, binding energy, deposition, chemical reactivity, and interactions between these processes as well as studies of surface structure, morphology, and surface group properties.
c. Characterization of chemical and biological interactions on solid surfaces including interfaces between materials and the surface. Areas of interest include transport, deposition, reactivity, and removal of biological and chemical compounds of interest, material interactions and properties arising from physical or biological synthetic processes, and enabling models and theory of interfacial interactions or processes that may relate to bulk properties.
d. Modeling for advanced materials processes as it relates to chemical-biological materials and sensors including processing parameters, structure property relationships, surface interactions and performance of materials and sensors with respect to chemical/biological exposure, decontamination, aging and use in extreme temperatures.
e. Utilization of novel manufacturing processes such as 3-dimensional bio-printing, integrated heterogeneous materials (i.e. Metal-Organic Frameworks) and in-situ polymerization and/or component integration during processing; advance fundamental scientific understanding of particle dispersion for novel utilization of next generation obscurants with novel pyrotechnics in areas such as disrupting command, control, and communications; investigate advanced/multispectral obscurant payload or concealment/camouflage/deception/false targets resulting in overall signature management or sensor defeat.
16. ANALYTICAL TOXICOLOGY:
a. Biomarker Discovery; determination of novel biomarkers of CW agent exposure.
b. Funding Category C: Tissue Imaging; development of mass spectrometry based tissue imaging techniques for CW agent exposure studies.
c. Antibody Production; development and production of butyrylcholinesterase antibodies for animal species that can be used for immunoprecipitation.
d. Materials Toxicity Assessment; development of assays that will examine the toxicity of materials both pre and post contamination with CW agent.
e. Synthesis; the synthesis and characterization of standards for the analysis of amino acids or short chain peptide fragments with a CW agent moiety.
17. TARGET DEFEAT TECHNOLOGY APPLICATIONS: The target defeat technology program represents a class of military capabilities that leverages chemical and material science based phenomena to adversely impact military equipment and personnel. Non-kinetic vehicle/vessel stopping represents a significant technical area under the target Defeat Technology program. Areas of interest are:
a. Perform vehicle/vessel stopping technology investigations involving combustion chemistry which encompass research and development (R&D) and test and evaluation (T&E).
b. Perform vehicle/vessel defeat studies through other chemical means and vehicle/vessel defeat support technology development.
c. Model various antimateriel processes to include combustion process in various engines.
d. Conduct R&D and production of various chemically based antimateriel and non-lethal technologies such as: anti-traction materials, foams, microencapsulation, adhesives, malodorants, tagging tracking and locating technologies (to include biometrics-based technologies), riot control agents and abrasives.
e. Provide munition system design to deliver a variety of non-lethal payloads.
f. Perform modeling and simulation for transport and diffusion phenomena associated with non-lethal riot control agent and smoke disseminations to determine area coverage, concentration, and dosage for system effectiveness evaluation.
g. Perform antimateriel studies designed to decompose, degrade and/or destroy selected military materiel and/or industrial production support equipment. Note: antimateriel studies can include theoretical review of potential technologies, feasibility determinations at the laboratory bench level, and/or field testing to include the possibility of employing fully operational identified equipment.
h. Conduct studies and investigations to identify or develop non-lethal antipersonnel effects.
i. Conduct Model-Based Systems Engineering (MBSE) to support system and subsystem evaluations to examine how selected target defeat technologies and system requirements are met and to determine the need for new ideas and alternatives to fill gaps discovered or analyzed. Note: Knowledge and experience are required with MBSE software tools such as Vitech CORE Spectrum and IBM Rational System Architect.
18. ARTIFICAL INTELLIGENCE/ MACHINE LEARNING: Artificial Intelligence (AI) technology program represents the possibility for machines to learn from experience, adjust to new inputs and perform human like tasks. AI refers to computer systems capable of performing complex tasks that historically only a human could do, such as reasoning, making decisions, or solving problems. Areas of interest are:
a. Potential use of reactive machines, i.e. AI systems that have no memory and are task specific.
b. Use of limited memory machines.
c. Theory of mind.
d. Development of algorithms for decision making based on input from multiple sources.
e. Advanced model development and validation.
19. MICROSENSORS: Size, weight, power and cost (SWaP-C) are the key primary driving factors during sensor development. Current system and component (i.e. batteries, communications, sensors, etc.) technologies offer poor performance and are large, heavy, with high power demands, and high cost, which limits the application/deployment of hazardous material (solid, liquid, and/or gas) sensing solutions. Interested in an integrated, easy-to-use, easy-to-maintain, high accuracy platform agnostic sensing capability that collects and detects hazards in solid, liquid, and/or gas phases over complex operational areas.
20. ADVANCED MANUFACTURING/ MATERIAL SCIENCE: Advanced manufacturing is the use of innovative technology to improve products or processes with modern technology. Advanced manufacturing industries increasingly integrate new innovative technologies in both products and processes. Use of a potential combination of traditional manufacturing and additive manufacturing. Materials science and engineering seeks to understand the fundamental physical origins of material behavior to optimize properties of existing materials through structure modification and processing, design and invent new and better materials, and understand why some materials unexpectedly fail.
Are there any additional benefits I would receive?
Access to multiple award pathways, including:
Procurement Contracts
Cooperative Agreements
Other Transactions (OTs) for prototypes
Potential for follow-on production awards after successful prototype development (for OT awards)
Opportunity to work directly with DEVCOM CBC technical teams and facilities
Exposure to DoD mission-critical problem sets and future funding pathways
What is the timeline to apply and when would I receive funding?
Deadline: Not specified — this BAA is continuously open for up to five (5) years
Preproposal decisions: Typically within 60–90 days of submission
Full proposal timing: Submitted only after invitation (timeline specified in RFP)
Award timing: Not specified; depends on evaluation, priorities, and funding availability
Where does this funding come from?
U.S. Army Combat Capabilities Development Command (DEVCOM) Chemical Biological Center (CBC)
Managed by Army Contracting Command – Aberdeen Proving Ground (Edgewood Contracting Division)
Authorized under:
Federal Acquisition Regulation (FAR)
10 U.S.C. §4021 and §4022 (Other Transactions)
41 U.S.C. §6305 (Cooperative Agreements)
Who is eligible to apply?
Educational institutions
Nonprofit organizations
Private industry (including small businesses)
Additional notes:
Non-traditional defense contractors and small businesses are especially relevant for OT awards
Foreign organizations may apply, subject to compliance requirements
Awards are made to organizations, not individuals
What companies and projects are likely to win?
Projects are evaluated primarily on:
Technical merit (highest priority)
Military and program relevance to CBRNE defense
Innovation and scientific rigor
Alignment with DEVCOM CBC mission areas
Feasibility and clarity of approach
Availability of funds
Strong proposals will:
Address clear defense needs
Demonstrate novel, innovative approaches
Reduce programmatic risk for the Army
Align directly with listed mission areas
Are there any restrictions I should know about?
Key restrictions include:
No funding for proposal preparation costs
Projects must not focus on specific system/hardware development (except concept demonstration)
Foreign influence and security risks are assessed through Army Research Risk Assessment (ARRP)
Disclosure requirements for funding sources and affiliations (NSPM-33 compliance)
Compliance required for:
Human subjects research
Animal research
Environmental regulations
Awards depend on availability of funds
How long will it take me to prepare an application?
Preproposal (required first step):
Maximum 3 pages
Includes concept, scope, qualifications, and estimated cost
Full proposal (if invited):
Substantial effort with multiple sections (technical, management, cost, etc.)
Timeline for submission provided in RFP
How can BW&CO help?
BW&CO can support you to:
Identify the highest-probability mission areas for your technology
Develop a competitive preproposal strategy aligned to DEVCOM priorities
Translate your innovation into DoD-relevant language and positioning
Prepare a full proposal package (technical, management, cost)
Navigate OT vs contract vs cooperative agreement pathways
Ensure compliance with ARRP, NSPM-33, and DoD requirements
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.
Additional Resources
DIU: Robotic Exclusion & Engagement Framework (REEF)
Deadline: April 3rd
Funding Award Size: $500k -$2m
Description: Apply to the REEF CSO for funding to develop underwater detection, tracking, and defense systems for U.S. and UK applications. Deadline: 2026-04-03
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The Robotic Exclusion & Engagement Framework (REEF) is a bilateral U.S.–UK Commercial Solutions Opening (CSO) seeking technologies to detect, track, classify, and defeat underwater threats such as AUVs, UUVs, and semi-submersibles targeting ports and critical waterways. Solutions can address individual components or provide a full system, with preference for approaches that can integrate into a broader REEF architecture.
Selected vendors will work directly with U.S. and UK government teams and must be prepared to integrate and conduct in-water testing within 90 days of award.
Application deadline: 2026-04-03 23:59:59 US/Eastern Time.
How much funding would I receive?
Not specified in the solicitation, but typically will lead to awards between $500k - $2m.
What could I use the funding for?
Funding supports development and demonstration across four REEF components:
1. Detect, Track, and Classify
Subsea detection (bearing, range, tracking data)
Multi-sensor tracking and classification (including AI/ML)
False alarm and clutter reduction
Sensors (e.g., sonar, EO/IR, acoustic, magnetic, fiber optic sensing)
Deployable fixed and mobile systems (USVs, UUVs, UAVs, buoys)
Open architecture, MOSA-compliant systems
2. Defeat Capabilities
Non-kinetic: nets, barriers, bubble curtains
Kinetic: payloads, directed energy, physical disruption
Decoy systems
3. Data and Network Architecture
Secure, near real-time data transmission
Encrypted systems compliant with DoD interfaces
4. COP/C2 (Command and Control)
Common Operating Picture integration or standalone tools
AI/ML decision support
Multi-modal sensor fusion (AIS, radar, RF, acoustic, EO)
Are there any additional benefits I would receive?
Direct path to follow-on production without further competition under 10 U.S.C. 4022(f)
Opportunity for adoption across multiple DoD organizations
Collaboration with U.S. and UK government teams
Participation in technical development sessions
Integration into a broader multi-vendor system
What is the timeline to apply and when would I receive funding?
Application deadline: 2026-04-03 23:59:59 US/Eastern Time
Post-award requirements:
Participate in several week-long technical development sessions
Be ready for:
Integration with other systems within 90 days of Other Transaction award
In-water testing within that same timeframe
Where does this funding come from?
Commercial companies
U.S. and UK
Non-U.S. companies may apply, subject to export control compliance
Additional requirements:
Only one submission per vendor
Must clearly identify which REEF component(s) the solution addresses
Who is eligible to apply?
All sources capable of addressing the objectives of this CSO are eligible
Additional requirements:
Must comply with security requirements (including DoD classification guidance)
Must be able to operate in DoD cloud environments (IL5 with scalability to IL6)
What companies and projects are likely to win?
The government indicates preference for solutions that:
Show a credible path to a full REEF system
Are modular, scalable, and rapidly deployable
Comply with open architecture (MOSA)
Support the full Detect–Track–Classify–Defeat chain
Perform reliably in complex maritime environments
Can integrate with other vendors and systems
Both component-level and end-to-end solutions are encouraged.
Are there any restrictions I should know about?
Export Controls:
U.S. EAR and ITAR provisions apply (with UK-specific exemptions)
UK companies may use General Export Authorisation No. 001
Non-U.S. companies must comply with home-nation export laws
Submission limits:
Maximum 15 slides or 5-page whitepaper
Only one submission per vendor
Collaboration requirement:
Vendors must work with other vendors and government partners
How long will it take me to prepare an application?
Based on requirements:
A 15-slide or 5-page submission
Clear mapping to REEF components
This is structured for rapid preparation, especially for teams with existing technology.
How can BW&CO help?
Identify the strongest REEF component fit for your solution
Position your offering for system-level integration
Translate capabilities into clear defense outcomes
Ensure compliance with CSO format and evaluator expectations
Build a concise, high-impact submission (slides or whitepaper)
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($9,000 + 5%) available.
Additional Resources
Air Force: SAF/CDM Commercial Solutions Opening and Specific Calls
Deadline: April 25h, 2026
Funding Award Size: $500k -$5m
Description: Apply for Air Force CSO funding to modernize HR systems supporting 700,000+ personnel. Submit a white paper by 4:00PM Washington, DC Local Time, 25 April 2026.
Below is a brief summary. Please check the full solicitation before applying (link in resources section).
Executive Summary:
The Air Force is seeking innovative commercial solutions to modernize its fragmented HR technology environment supporting over 700,000 personnel. The system currently consists of over 118 disparate applications and 84 legacy systems, creating inefficiencies, data silos, and security risks.
This is a Commercial Solutions Opening (CSO) with a rolling submission model, but there is a key near-term deadline:
“Closed” Due Date for White Paper Submissions: 4:00PM Washington, DC Local Time, 25 April 2026
Submissions are still accepted after this date under the open period, but early submissions receive priority consideration. This is a strong opportunity for companies with capabilities in cloud, DevSecOps, data integration, and enterprise modernization to secure follow-on prototype or production work.
How much funding would I receive?
Estimated CSO Budget: $100 Million (for all awards under the CSO)
Award size: Not specified
Number of awards: Not specified
Funding per project: Not specified
Funding will be provided “from time-to-time” and no guarantees are made regarding availability.
What could I use the funding for?
1. Application Refactoring & Modernization
Re-architect legacy HR systems into modern, secure SaaS-based solutions
Reduce technical debt and reliance on outdated infrastructure
Transition systems built on platforms like Salesforce, ServiceNow, and Outsystems into a more sustainable architecture
2. DevSecOps
Implement CI/CD pipelines for continuous software delivery
Improve speed, security, and reliability of deployments
Embed security practices directly into the development lifecycle
3. Human-Centered Design (HCD) & Discovery
Use user-centric research and design methods to define requirements
Develop technical blueprints that reduce development risk
Improve user experience across HR systems supporting 700,000+ personnel
4. Enterprise Integration & API Development
Build reusable APIs to connect disconnected systems
Eliminate data silos across the HR ecosystem
Enable a unified data environment across platforms
5. Data Migration & Validation
Migrate data from legacy systems into secure cloud environments
Ensure data integrity, accuracy, and consistency
Support consolidation of duplicative data platforms
How to think about fit
Strong use cases will:
Directly address fragmentation, inefficiency, and security risks in the current HR ecosystem
Align with the Air Force’s shift toward agile, cloud-based, AI-enabled systems
Enable faster deployment, better user experience, and reduced sustainment costs
You may respond to one or multiple focus areas depending on your solution.
Are there any additional benefits I would receive?
Potential for follow-on production contracts or OTAs if prototype efforts are successful
Access to a streamlined acquisition pathway (CSO) designed for faster engagement
Opportunity to work on mission-critical systems impacting 700,000+ personnel
What is the timeline to apply and when would I receive funding?
White Paper
“Closed” Due Date for White Paper Submissions: 4:00PM Washington, DC Local Time, 25 April 2026
Open submissions continue after this date under the CSO
CSO Deadlines (Overall Program)
Due Date for Final White Paper Submissions: 4:00PM WASHINGTON, DC LOCAL TIME, 15 AUG 2026
Due Date for Final Proposal Submissions: 4:00PM WASHINGTON, DC LOCAL TIME, 15 SEP 2026
Last Day for Awards: 11:59PM WASHINGTON, DC LOCAL TIME, 30 SEP 2026
Process
Step 1: Submit White Paper (required)
Step 2: If selected, you will be invited to submit a full proposal
Government may review submissions on a rolling basis
Where does this funding come from?
Sponsor: Secretary of the Air Force (SAF), Concepts, Development and Management (SAF/CDM)
Authority: Section 879 of the FY2017 National Defense Authorization Act (Defense Commercial Solutions Opening Pilot Program)
Who is eligible to apply?
All sources capable of addressing the objectives of this CSO are eligible
Additional requirements:
Must comply with security requirements (including DoD classification guidance)
Must be able to operate in DoD cloud environments (IL5 with scalability to IL6)
What companies and projects are likely to win?
The government prioritizes solutions that:
Demonstrate breakthrough innovation, not incremental improvements
Address urgent mission needs and improve operational effectiveness
Enable rapid testing, prototyping, or proof-of-concept delivery
Reduce data silos, inefficiencies, and security risks in HR systems
Are there any restrictions I should know about?
White Paper is mandatory before any proposal submission
Proposals can only be submitted if requested by the government
Only fixed-price contracts or OTAs are allowed
Funding is not guaranteed and subject to availability
Must comply with export control laws (ITAR/EAR)
Potential conflict of interest restrictions for existing contractors
How long will it take me to prepare an application?
White Paper limit: Maximum 10 pages
Intended to be streamlined and low-cost to prepare
Exact preparation time is not specified, but the process is designed to minimize upfront effort before invitation to full proposal.
How can BW&CO help?
BW&CO can support you by:
Identifying the strongest focus area alignment for your solution
Positioning your concept for “innovation” vs. incremental improvement scoring
Structuring a 10-page White Paper that meets all requirements
Translating your product into DoD-relevant language and outcomes
Preparing you for proposal invitation and follow-on funding
How much would BW&CO Charge?
We have both fractional engagements ($250 an hour) and full engagements ($15,000 + 5%) available.